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Secrets.

Good secrets are possible: things like a tasty recipe, your unfinished album, or company staff payrolls. Privacy is lovely, but we swap it for convenience often.

But the cesspool of bad secrets farmed by the CIA and NSA are a toxic wasteland of bad secret information. Harbouring the waste is risky, in 2015 the NSA got hacked revealing the home address and personal details of 4 million employees! One good way to protect against such a breach would be to just delete the stuff and recycle the hard drives. Here is an astonishing one hour lecture by a hero named Kevin Shipp. https://www.youtube.com/watch?v=XHbrOg092GA Turns out the CIA put in charge of Kennedys assassination was fired by Kennedy earlier. That shows how quick the shadow government took control over. All attempts to curtail so far get sunk in classified quagmires, odd suicides and hits.

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A Class Action Application For Interim Orders For A Stay Of Proceedings Pending Reclassification Of Cannabis Via Judicial Review; And Of The Failure Of The Statutory Duties Of The EACD, MOH, HRC And Office of the Queens Council to the Parliament of NZ

Roll Your Own Injunction!

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As a random act of kindness, I quit my job at the time, and spent about 300 hours learning law and raising up this interim injunction to help in the case of a stranger, a man I had never met but who had been accused of growing 500 plants in Cambridge. I offered him accommodations at my house in Auckland (after his trip from Whangarei) and a lift to Hamilton to face the charges and travelled their with him that day.

This is a class action interim injunction against various agencies of crown this year. I did not actually serve the notice to the crown – well actually I did try but it was not accepted for filing by the registrar – but don’t worry, in 2017 I fully intend to serve this to the crown at the High Court in Auckland.

 

Without further ado… the action:  (The following is a full text paste from the official documents linked above)

 

 

 

 

In the District Court of New Zealand, Whangarei / Auckland / Hamilton Registry

IN THE MATTER OF THE Judicature Act 1908, Misuse of Drugs Act 1975, The Health Act 1956, Bill of Rights Act 1990, UN DRIPs 2007, Magna Carta 1215, King v Penn 1670 (Tower of London); Orders of King Henry 1533 and Elizabeth 1563; A Class Action Application For Interim Orders For A Stay Of Proceedings Pending Reclassification Of Cannabis Via Judicial Review; And Of The Failure Of The Statutory Duties Of The EACD, MOH, HRC And Office of the Queens Council to the Parliament of NZ

Crown versus Xxxxl                         CRI-2015-0X9-00XX19 (upcoming hearing 0X# November 2016)

Crown versus Xxxxxxxn       CRI-2014-0X4-029XX; CRI-2015-0X4-0085XX; and CRI-2015-404-00X365 (sentenced 29/10/2015, high court appeal 15/12/2015)

Crown versus Citizens         class action interim injunction on behalf of 46% of NZ citizens hereby initiated

BETWEEN                         Rxxxx Xxxxxt Xxxxl, of Whangarei, Engineer Applicant
Xxxxxs Xxxxxr Xxxxxxxn, of Auckland, Professional Drummer, Website Consultant, Law Enthusiast Applicant
The Citizens of New Zealand Class Action Applicants

AND                                 Dr Keith Bedford, of Auckland, Toxicology, The Expert Advisory Committee on Drugs Respondent failure of statutory duty in Misuse of Drugs Act 1975

AND                                 Dr Chai Chuah, of Auckland, Director General Ministry of Health Respondent Section 3A Failure to adhere to the spirit of the Function of Ministry of The Health Act 1956

AND                                 David Rutherford, Chief Commissioner of the Human Rights Commission Respondent breach of the spirit of part 2 section 17 of the NZ Bill of Rights Act 1990; breach of article 24, clause 1 of the UN Declaration on The Rights of Indigeonous Peoples 2007

AND                                 Una Jagose Solicitor General and/or Chris Finlayson Attorney General of New Zealand Respondent general and systemic failure in parliaments poor response to UNHRC5; Law Commission 20112; clarification of Mckenzie friend counsel T Xxxxxxxn; claim of right; jury nullifcation by direct address to jury to strike the prohibition with fresh bias and great prejudice.

Interlocutory Application without notice by the Applicant for interim injunction against the Respondents

To the Registrar In the District Court of New Zealand, Whangarei / Auckland / Hamilton

And To the Respondants

This document notifies you that that the self represented applicants, Xxxxl, Xxxxxxxn, and the Citizens of New Zealand, hereby apply for the following interim and permanent injunctions, restraining the police and enforcing duty on the EACD:

  1. Removal of the plant Cannabis Sativa and extracts from the schedules of the misuse of drugs act, mainly because a plant genus can’t be a pharmaceutical drug.
  2. Addition of the drugs THC, THC-A, CBD, CBN, CBC, CBG, CBC and potentially about 80 other cannabinoids and volatile terpenes, plus the very approximate $7 to $80 million dollars (at ~$1 million ballpark figure) to test each at the ESR.
  3. Good faith waiver of our class action $4 billion damages claim in return for swift action by the MOJ including the immediate and comprehensive cessation of all arrests, prosecutions, incarcerations, probations, and digitisations involving the criminal histories of those accused of such victimless crimes of thought, who only wish to experience freedom in the privacy of their own home hurting nobody.

You must file in this registry of the court a statement of defence to the plaintiff’s claim (a copy of which is served [1] with this notice). You must do this within 25 working days after the date on which you have been served with this notice. If you do not, the plaintiff may at once proceed to judgment on the plaintiff’s claim, and judgment may be given in your absence.

If a trial of the proceeding is necessary, it will be held in this court at Whangarei / Auckland / Hamilton at a time to be fixed by the court.

The grounds on which the each order is sought are as follows:

  1. The application for an interim injunction is made without notice because requiring the applicant to proceed on notice would cause undue delay or prejudice to the applicant, Rxxxx, who has been through a number of legal aide representatives whom have all resigned due to lack of faith in the concept of jury nullification, and a selfish unwillingness to risk reputation by being seen to take on cases unlikely to result in justice for the accused.
  2. The respondents have been advised of the importance of their statutory duties by ourselves on multiple occasions via attempted prosecutions by us such as on 23 June 2015, 21 February 2016, 16 August 2016, and today.
  3. The Crownlaw guidelines on the decision to prosecute not only the likelihood of successful prosecution, but on reasonable notions of public interest, the obsolescence of laws, and the interests of efficiency. My injunction shines a multi-dimensional light on the hyper-unjust prohibition of a sacramental flowering plant called Sativa who’s name in Greek means useful [2].
  4. There’s a saying: that laws can be passed or crushed by the ballot box, the jury box, or the ammo box.

I promise to the best of my knowledge this is made in accordance on Rules 3.52.5 3.52.28 of the District Court Rules 2009.

 

 

Signature:   _________________________________________

Rxxxx Xxxxl, Applicant in person

Date:                 /           /

 

 

Signature:   _________________________________________

Xxm Xxxxxxxn, Applicant in virtual, and authorised counsel to the Applicant like Rxxxx Xxxxl.

Date:                 29/12/16

If you file a statement of defence in the court, you must also provide the applicants with initial disclosure o           f documents in accordance with rule 8.4.

If you file a statement of defence in the court, you will be notified of the date and time of the first case management conference.

The purpose of the conference is to assist the parties in the just, speedy, and inexpensive determination of the proceeding, to make directions as to the conduct of the proceeding, and, where practicable, to make interlocutory orders. The parties will also be assisted to identify, define, and refine the issues in dispute.

You must prepare for and attend the first case management conference. You will be expected to have discussed with the applicant the matters set out in Schedule 5 of the High Court Rules. You or your solicitor must file a memorandum relating to the procedural matters set out in rule 7.3 of the High Court Rules.

 

 

Signature:   _________________________________________

Name:

Date:                 /           /

(Registrar/Deputy Registrar*)

*Select one.

Note: Please carefully read the memorandum attached to this notice.

In the District Court of New Zealand, Whangarei / Auckland / Hamilton Registry

IN THE MATTER OF THE Judicature Act 1908, Misuse of Drugs Act 1975, The Health Act 1956, Bill of Rights Act 1990, UN DRIPs 2007, Magna Carta 1215, King v Penn 1670 (Tower of London); Orders of King Henry 1533 and Elizabeth 1563; A Class Action Application For Interim Orders For A Stay Of Proceedings Pending Reclassification Of Cannabis Via Judicial Review; And Of The Failure Of The Statutory Duties Of The EACD, MOH, HRC And Office of the Queens Council to the Parliament of NZ

Crown versus Xxxxl                         CRI-2015-0X9-00XX19 (upcoming hearing 29 Sept 2016)

Crown versus Xxxxxxxn       CRI-2014-0X4-029XX; CRI-2015-0X4-0085XX; and CRI-2015-404-00X365 (sentenced 29 October 2015, high court appeal 15 December 2015)

Crown versus Citizens         class action interim injunction on behalf of 46% of NZ citizens hereby initiated

BETWEEN                         Rxxxx Xxxxxt Xxxxl, of Whangarei, Engineer Applicant
Xxxxxs Xxxxxr Xxxxxxxn, of Auckland, Professional Drummer, Website Consultant, Law Enthusiast Applicant
The Citizens of New Zealand Class Action Applicants

AND                                 Dr Keith Bedford, of Auckland, Toxicology, The Expert Advisory Committee on Drugs Respondent failure of statutory duty in Misuse of Drugs Act 1975

AND                                 Dr Chai Chuah, of Auckland, Director General Ministry of Health Respondent Section 3A Failure to adhere to the spirit of the Function of Ministry of The Health Act 1956

AND                                 David Rutherford, Chief Commissioner of the Human Rights Commission Respondent breach of the spirit of part 2 section 17 of the NZ Bill of Rights Act 1990; breach of article 24, clause 1 of the UN Declaration on The Rights of Indigeonous Peoples 2007

AND                                 Chris Finlayson Solicitor General of New Zealand Respondent general and systemic failure in parliaments poor response to UNHRC 5; Law Commission 20112; clarification of Mckenzie friend counsel T Xxxxxxxn; claim of right; jury nullifcation by direct address to jury to strike the prohibition with fresh bias and great prejudice.

Memorandum of counsel to the Applicant 

Advice: Although you do not have to employ a solicitor for the purpose of this proceeding, it is recommended that you consult a solicitor about this matter immediately. However, a company or other corporation that wants to defend this proceeding or appear at any hearing must consult a solicitor immediately because—

(a) it can only carry on a proceeding in the court by a solicitor; and

(b) it cannot appear to conduct a proceeding except by counsel (unless there are exceptional circumstances).

Legal aid: If you cannot afford to meet the cost of the proceeding, you may be entitled to assistance under the Legal Services Act 2011.

The plaintiff has applied for legal aid for the purpose of this proceeding.

Statement of defence: If the last day for filing your statement of defence falls on a day on which the registry of the court is closed, you may file your statement of defence on the next day on which that registry is open.

In calculating the time for filing your statement of defence you must disregard the period that commences with 25 December and ends with 15 January.

If you file a statement of defence, you must serve a copy of it on the applicants who have given an address for service. This must be done within the same period of time you have for filing the statement of defence.

Counterclaim: If you have a counterclaim against the plaintiff, you must file a statement of that counterclaim in the registry of the court, and serve it on the applicant and on any other person against whom the same claim is made. This must be done within the same period of time you have for filing a statement of defence.

Witnesses: Summonses for the attendance of witnesses will be issued on application at the registry of the court.

Registry hours: The registry hours of the court are from 9 am to 5 pm, except on court holidays.

 

Addresses for service


Rxxxx Xxxxxt Xxxxl
Applicant

nager@legalise.org.nz

Xxxxxs Xxxxxr Xxxxxxxn
Applicant, and council to Xxxxl

International Drummer, Recording Artist, Web Designer, Law Reform Enthusiast
xxxxxxs@legalise.org.nz

The Cannabis Consuming People of New Zealand
Future Class Action Applicant

THE EACD
Dr Keith Bedford
Respondent

Auckland, Toxicology, The Expert Advisory Committee on Drugs. The Committee is administered by a Secretariat comprised of Ministry of Health officials and advisers, as required.

EACD Secretariat
c/o Regulatory Practice and Analysis
Medsafe
Ministry of Health
PO Box 2013
Wellington
eacd@moh.govt.nz
keith.bedford@esr.cri.nz

THE MINISTRY OF HEALTH
Dr Chai Chuah, of Auckland, Director General Ministry of Health
Respondent

Ministry of Health
PO Box 5013
Wellington 6140
chai_chuah@moh.govt.nz
SSC-Media@SSC.govt.nz
psychoactives@moh.govt.nz

THE HUMAN RIGHTS COMMISSION
David Rutherford, Chief Commissioner of the Human Rights Commission

Respondant

Level 7, The AIG Building, 41 Shortland Street, Auckland
PO Box 6751, Wellesley Street, Auckland 1141
infoline@hrc.co.nz
roberth@hrc.co.nz

Una Jagose Solicitor General and Chris Finlayson Solicitor General of New Zealand
Respondant

Level 3
Justice Centre
19 Aitken Street
Wellington, 6011
New Zealand
c.finlayson@parliament.govt.nz
oia@crownlaw.govt.nz

 


Statement of claim

 

Filed by                                    Rxxxx Xxxxl, the applicant in person.
And; for many other persons:        The Citizens of New Zealand and Rxxxx Xxxxl.

The plaintiff claims:                 The Right to an injunction and Judicial Review

UNDER THE                             Judicature Act 1908, Misuse of Drugs Act 1975

IN THE MATTER OF AN APPLICATION FOR JUDICIAL REVIEW OF THE FAILURE OF THE STATUTORY DUTIES OF THE EACD AND INTERIM ORDER FOR STAY OF PROCEEDINGS PENDING RECLASSIFICATION OF CANNABIS

IN THE MATTER                        of breach of natural justice, breach of democracy.

AND                                         of removing, in its capacity of administration of the act, and due to overwelming evidence in support of the medicinal use of Cannabis Sativa and it’s variant straings, all mention of Cannabis plant and extracts in any schedule of the Misuse of Drugs Act 1975, an act which is solely administered by the Ministry of Health.

AND                                         of breach of Section 3A of The Health Act 1956 in regards to the Function of Ministry in relation to public health; by failure to carry out it’s core founding function of improving, promoting, and protecting public health in relation to Cannabis.

AND                                         of contravention of part 2 section 17 of the NZ Bill of Rights Act 1990 in relation to Freedom of thought, conscience, and religion. Namely that everyone has the right to freedom of thought, conscience, religion, and belief, including the right to adopt and to hold opinions without interference.

AND                                         of contravention of article 24, clause 1 of the UN Declaration on The Rights of Indigeonous Peoples 2007; expressly that Indigenous peoples have the right to their traditional medicines and to maintain their health practices, including the conservation of their vital medicinal plants, animals and minerals. Indigenous individuals also have the right to access, without any discrimination, to all social and health services.

AND IN THE MATTER                of the resulting financial, physiological and psychological damages arising from punishments out of all proportion to the “crimes” commited, and resulting from the lack of access to appropriate herbal medicine

 

Causes of action:

 

  • Failure to reclassify Cannabis in a timely fashion, post 2000 ammendments
  • Failure to consider the advancement of science in a timely fashion
  • Failure to heed advice of expert bodies in regards unpopular, obsolete law
  • Observed abuse of discretionary power by Hamilton police

 

Affidavit of Xxm Xxxxxxxn in support of application for injunction to remove the plant Cannabis and herbal extracts from schedules of the Misuse Of Drugs Act 1975

 

I, Xxxxxs Xxxxxr Xxxxxxxn, of Ponsonby, Auckland, 39 years of age (13/0X/19XX) hereby wish to make this formal application for an emergency interlocutory with a crown representative, a member of the EACD, the Auckland commissioner for Human Rights, in Auckland, before Thursday 29 September 2016, that being the day of an upcoming prosecution of a wholly innocent man of thought crime in the Hamilton district court:

Crown v Xxxxl CRI-2015-0X9-00XX19 Thursday 29 September 2016;

15019008168 Cultivates (lead charges for 500 plants in Cambridge found 1 October 2015)

All charges: 15019008169 / 15019008170 / 15019008171 / 15019008172 Possess Equipment to Cultivate / 15019008767 / 15019008768 / 15019008769 / 15019008770 / 15019008772

And my own personal application for Habeas Corpus to overturn or hide my conviction and sentence on 29 October 2015, and my requeset to be able to work as a musician which were dismissed at the High Court on 15 December 2015.

Crown v Xxxxxxxn CRI-2014-0X4-029XX and CRI-2015-0X4-0085XX; and CRI-2015-404-00X365

And a class action lawsuit I’m preparing against the government on behalf of the 400,000 people in New Zealand whom have tried the prohibited cannabis once in their lives, seeking potential damages of $4 billion but including a waiver settlement in return for our remedy.

I hereby seek an urgent interlocutory order or a direction relating to a matter of procedure; subject to the Supreme Court Act 2003 [3].

The matter of procedure relates to at least eight areas:

  1. ambiguity in the text of the law;
  2. the inheritance of laws from England;
  3. the interpretation of the meaning and purpose of a jury;
  4. the accused ability to address the jury directly or via Mckenzie friend;
  5. inaccuracies in the text of laws;
  6. constitutional issues, the rights of the indigenous, the public interest etc:
  7. reduction in needlerss torture and punishment
  8. reduction in costs to the government
  • I hereby state claim that my request to review cannabis sativa is valid and in the public interest, and should proceed to a hearing. A judicial review is referred to as supervisory jurisdiction – reflecting the role of the courts to supervise the exercise of power by those who hold it to ensure that it has been lawfully exercised. The Judicature Amendment Act 1972 [4] saught to simplify the old matters of prerogative writs [5]; The practical position is that any exercises of power are reviewable by the courts that in substance have important public consequences. At its most basic level, judicial review is available when an Act of Parliament creates a discretionary power for public officials to exercise – be they Ministers, Chief Executives of Government Ministries, or Ministry employees – and somebody adversely affected by the exercise of that power challenges the decision on the basis that the person exercising it has not acted consistently with the power given by the Act, for example, by misinterpreting the provision giving it. Seen in this way, judicial review essentially involves the courts ensuring that the law is being followed when power is exercised in a manner that affects people. There are many ty­pes of decision that can be challenged by way of judicial review, and various bodies exercising “public” powers or functions that can have their decisions reviewed by the court, but focusing on this core aspect of judicial review provides the clearest insight into the essence of it.
  • I involve the Minister, for his part as it is the ministry of Health that oversees this act, and his refusal to reclassify cannabis out of the misuse of drugs act entirely due to cannabis sativa and it’s extracts being the genus of a a plant species and not a pharmaceutical drug compound; and that he failed in his statutory duty to do so as stated binding the crown in the spirit and good intention of the opening of the Health Act 1956 in it’s promise to provide positive health outcomes for kiwis.
  • I involve the Chief Commissioner of the Human Rights Commission to respond to my claim of breach of the spirit of part 2 section 17 of the NZ Bill of Rights Act 1990; and of breach of article 24, clause 1 of the UN Declaration on The Rights of Indigeonous Peoples 2007; and of the simple right to live in a plant based society.
  • I involve the Solicitor General of New Zealand to respondent to the claim of failure of our government in it’s responsibility and/or statutory duty to respond to the UNHRC 5th periodic report; and failure to provide justice by allowing the courts to bar the accused from presenting their defence of jury nullifcation by addressing the jury directly to strike down the prohibition law.
  • To answer questions relating to the inheritance of our laws from England post 1840, a review of guidance provided by the judiciary as to the true purpose and history of juries, and their initial purpose as the citizens defenders from abusive powers and whether the purpose of a jury in England is the same as in New Zealand.
  • Recent scientific evidence has come to light that shows the plant and concentrated extracts of Cannabis Sativa, Cannabis Indica, and Cannabis Ruderalis, listed in schedules of the Misuse of Drugs Act 1975 do in fact have therapeutic value as medicines; and should therefore be removed from the act, prior to the addition of the individual compounds in order to provide time to study them.
  • The fact that cannabis is a plant and not a drug appears to have created a deadlock at the EACD [6], indication the assistance of a judicial review could be due.

During the April 2016 meeting of the following minutes are noted, shown below in italics, where members note that only “one molecule of a controlled substance to be present in preparation” whereas cannabis is not a molecule.

[redacted] advised that currently, if a practitioner wishes to prescribe a cannabinoid or products that contain cannabinoids, they have to make an application to the Minister. Currently there are no products containing only CBD that are approved medicines both domestically and internationally. There are however, a number of non-pharmaceutical products available. It was noted that there was a difference of opinion between ESR and MoH regarding whether or not CBD should be considered a controlled drug or not. The Therapeutic Goods Administration (TGA) in Australia have recently down-scheduled CBD to a prescription only medicine with less than two percent of other cannabinoids as most CBD extracts contain small amounts of tetrahydrocannabinol (THC) due to the difficulty and associated cost to separate the two substances. The Misuse of Drugs Act (MoDA) only requires one molecule of a controlled substance to be present in a preparation for it to be captured as a controlled drug.

There is an entry in the Medicines Regulations for CBD as a prescription medicine, however, if it is also considered a controlled drug, then MoDA acts as the dominant piece of legislation.

  • In relation to the plant Cannabis the contravention of the following UN Declaration [7]:“Indigenous peoples have the right to their traditional medicines and to maintain their health practices, including the conservation of their vital medicinal plants, animals and minerals. Indigenous individuals also have the right to access, without any discrimination, to all social and health services. “ – The United Nations
  • Right honorable Peter Dunne, member of parliament, recently gave his approval [8] for the use of Cannabis Sativa whole plant extracts to be used for therapeutic use in the treatment of a severely epileptic patient in Wellington. This fact alone is entirely sufficient evidence for the immediate removal of cannabis sativa from the act.

Dunne approves one-off use of ‘Elixinol’ on compassionate grounds; a cannabidiol (CBD) product from the United States to be administered by clinicians treating Wellington patient Alex Renton:

“I have also considered the absence of any other treatment options, the low risk of significant adverse effects, and the conclusion reached by the hospital ethics committee from an individual patient perspective.” – Peter Dunne

  • Cannabis Sativa has been shown to reduce incidence of Glaucoma[9]
  • Cannabis Sativa has been shown to be effective in the treatment of multiple sclerosis[10].
  • Cannabis Sativa has been shown to be effective in the inhibition of many cancers[11]:, such as lung, brain, bladder[12].
  • The Sativex datasheet says it’s product it non-toxic to the liver[13].
  • Studies of dogs and monkeys found 15,000 joints in 15 minutes was a fatal dose for those unfortunate animals, but the study is likely to have been incorrect science. The numbers yielded by the bunk study by my calculations an extrapolated LD50 (lethal dose in 50% of people) of 92 grams of pure THC for a person of 72 kgs, taken inside 15 minutes. Judge Young of the US DOJ said in Docket No.86-22 on September 6, 1988 comments about the LD50 of cannabis[14].
  • The endocannabinoid system is the most widely spread G type receptors in the modern brain, however it does not affect the brainstem like alcohol does, and therefore can not be the cause of a fatal overdose. THC must therefore be non-toxic.
  • The bodies own Endocannabinoid system is named after cannabis and it is a diverse group of neuromodulatory lipids – such as Anandamide – and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as “endocannabinoids” and are physiological ligands (electron pair donors) for the cannabinoid receptors[15]; The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase; The cannabinoid receptors CB1 and CB2, are two G protein-coupled receptors that are located in the central and peripheral nervous systems; The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of physiological processes, including motor learning, synaptic plasticity, appetite, and pain sensation.
  • For the purposes of conducting additional studies in preparation for application for legal sale via the Psychoactive Substances 2013 act[16], I respectfully request that the Court considers my application for removal of Cannabis and it’s extracts from all schedules of the Misuse of Drugs Act 1975.

 

Interlocutory Questions for the EACD

  • For his committee’s part and as a local member the EACD’s effective refusal to reclassify cannabis out of the misuse of drugs act entirely due to cannabis sativa and it’s extracts being the genus of a a plant species and not a pharmaceutical chemical drug compound; and that he has failed in his statutory and ethical or moral duty to do so under the Misuse of Drugs Act 1975; 2000 Ammendments which created the committe to oversee what would become “Legal Highs”.
  • In the context of the Misuse of drugs act, what exactly is a drug?
  • Is Viagra the worlds only recreational prescription drug? What others exist?
  • It is not hearsay to say:A pharmaceutical drug is an element or known compound that affects the mind and/or body in a clinically recognised and scientifically repeatable manner. The compound can be purified and studied.
  • Scientifically formulated drugs are virtually never plants, they are pure extracts.
  • Cannabis sativa is the genus of a plant. It is not a drug. It’s inclusion in the schedules is unique. No other banned or prohibited plants exist; certain noxious weeds can not be sold at garden stores, but it is not prohibited to possess or cultivate them.
  • I request an interim injunction requesting the EACD to consider removing plant genus cannabis and it’s extracts by amendment, and suggest the same or intended effect could be discovered by studying the following compounds:

THC – Delta-9 Tetrahydrocannabinol, THCA – Tetrahydrocannabinolic Acid, THCV – Tetrahydrocannabivarin, CBD – Cannabidiol, CBN – Cannabinol, CBG – Cannabigerol, CBC – Cannabichromene, Terpenes – diverse group of organic HydroCarbons (C5H8).

 

Supreme Court Judicial Review Interlocutory

 

  • The United Nations has twice put New Zealand on notice for poor performance in regards human rights, re-iterating the initial warning from the 4th report in the 5th periodic report[17]
  • Since our law is based on English law prior to 1840, is New Zealand subject to the same UK court precedents prior to 1840?
  • Under the Crimes Act 1961, would it be considered wilful perversion of justice to distribute this[18] informational flyer about Jury Nullification to all houses in Hamilton?
  • Do the citizens of New Zealand have the right to freedom of thought?
  • According to the Bill of Rights we are supposed to have freedom of religion, yet this does not seem to stretch to freedom of culture. Why is that?
  • Since we currently have the legal right to perform acts to alter our minds such as meditation/skydiving/spinning to dizziness/hyperventilating; and since this right to alter our minds extends to the cultural practices of alcohol, caffeine and recreational drug viagra; then shouldn’t this right also extend to cultural practices of altering our minds using other less harmful chemicals instead, even if these cultural practices seem alien so long as they harm no other person?
  • In some countries you could be punished just to think of gay sex.

Yet thought crimes are indefensible.

In NZ, recently bills have been proposed to reverse the convictions of homosexual men accused of performing sodomy or anal sex – this non-crime is essentially similar to drug non-crime in that it is a non-crime of thought as well as prosecutor-led court action that is victimless, lacks a witness and is also complainant-free.[19]

  • Does the state recognise or deny our right to the freedom to develop our own unique human personality, our cultural behaviors, lifestyles, religions, traits and customs, so long as it does not harm ourselves physically or mentally, nor anyone else or nor anyone or other nation states property in any measureable way that’s reasonable?
  • Recently the Mexican supreme court ruled in favour of the right to develop a personality and stuck down the ban on the cannabis plant for contravening this, so I felt this was relevant to my interlocutory application at the Supreme Court.
  • What justification exists or why should New Zealand citizens have a right to a trial by a jury of one’s peers and is this right enshrined in any legislation currently?
  • Does the court agree that one good purpose of a jury is to protect citizens from overzealous governments and courts by forming a safety valve or sorts for aberrant or obsolete laws?
  • Our nation and many others are based on the universal and historic text of the Magna Carta of 1215 AD which establishes this and we intend to mount a defence basd primarily on the idea a jury can protect citizens from bad laws[20].
  • Should the criminal defence be allowed to instruct juries of their civic responsibility to deliver justice to their fellow citizens perhaps over and above the duty to law and to the crown? If not, why not? Does this conflict with the Magna Carta?
  • Our defence depends on our ability to address the jury; to educate on our countries legal history and laws and to instruct the jury in this case to strike out the Misuse of Drugs Act, and to declare the fruits of the search warrant null and void and that any obstruction to our right to present our natural defence is a direct afront to our understanding of the system and counter to the entire reason for having jury trials!

The cases are:

  1. a) The King v William Penn and Mead. 1670 Tower of London, United Kingdom[21];
  2. b) The Crown v Murnane 2008; Waihopai, New Zealand[22].

In both cases the jury acquitted the accused of “thought crimes” despite considerable evidence, due to the fact that a thought crime is not defendable.

  • The right to present a defence as requested by the barons in Magna Carta by The King of England was given under duress of his life and the capture of London castle. If the citizens right to mount a defence to the jury is threatened this must necessarily end in violent conflict surely?
  • Does the jury have the option to find any defendant not guilty even if doing so may require accepting the evidence of the crime as factually committed by the accused and yet also simultaneously determine the law itself to be invalid, irrelevant, obsolete, or not in the public interest in this particular case?
  • In The King v William Penn, was a matter of a victimless crime and obsolete law. Penn was able to admit the truth of the statements of fact but still plead not guilty claiming the law to be incorrect, and by addressing the jury for compassion in the shadow of tyranny.
  • Is it sensible or responsible for crown prosecution to proceed with Crown v Xxxxl CRI-2015-0X9-00XX19 if the defendant is indicating support from myself to mount exactly such a defence of jury nullification and a simultaneous claim of right under the Crimes Act 1961 or should parliament or the judiciary intervene to clarify its position on the matter?
  • Considering the mountain of evidence against my Mckenzie friend Xxxxl, and guilty admission in statements to police, an entire jury trial seems an expensive waste of tax payers money.
  • The fact that an accused person acted without “claim of right” is an element of this offence with must be proved by the prosecution beyond reasonable doubt. It enables a defendant to advance at their trial that they genuinely believe that what they were doing was lawful, regardless of the reasonableness of that belief.
  • In summing up the Waihopai Three case to jurors, Judge Stephen Harrop said if the Waihopai Three believed they were acting lawfully, even if they were mistaken in that belief, they must be acquitted.

The right of defence was that they acted urgently to save another life.

  • Considering the recommenations in The Law Commission Report 2011[23] generated over 3,800 submissions, and ultimately recommended repeal of the act in Chapter 14 R1, why has he not called for the repeal of the act?

 

Questions for Humans Rights Commissioner

  • For his part by denying my Mckenzie friend Xxm Xxxxxxxn his legitamate claim to an indigeonous Customary right of use of traditional plants, and to clarify the difference between freedom of religion and freedom of culture, and a review of his commissions lack of action in regards the UNHRC 5th periodic report.
  • ###
  • My initial human rights complaint was declined by from Robert Hallowell, legal counsil for the HRC on the basis I am not an indigeonous person[24].
  • I have never in my life harmed anyone or property, nor have I ever been charged nor convicted of any crime involving any person or property.
  • I was the victim of police harassment and multiple unwarranted searches of my home during 2015, including an entire search of my house and locked bedroom when I was not home due to “the smell of cannabis” being smoked by one of my flatmates in our free standing villa. The police did not knock and came around the back of the house. By September I had begun to record the date/times of the visits and counted 6.
  • Regarding being actively denied the ability to work by probation during my 6.2 month sentence of community detention on Cannabis supply charges; on three separate occasions I presented in written offers of work from three different employers that I could willfully accept (Appendix A), but each time and finally in escalation from my probation manager up to a managerial level written refusal from the department involving the superstition of likely future offending on the dates, based on false propositions I’d likely offend again during the specific hours of my employment, which were at night time.
  • Community detention is a home based rehabiliative custodial sentence given to offenders deemed at low risk to society, and allows an offender to work during the sentence.
  • As such this is a contravention of the Human Rights Act 1993 part 2 Unlawful discrimination, which relate to discrimination in employment matters: It shall be unlawful for any person concerned with procuring employment for other persons or procuring employees for any employer to treat any person seeking employment differently from other persons in the same or substantially similar circumstances by reason of any of the prohibited grounds of discrimination, in my case on my religious belief, ethical belief, my race or aparent lack thereof, my abnormally high psychological function.
  • I also believe the department may have taken some of my political opinions to heart in preventing my access to employment during this time. My probation officer suggested that I could take up other employment options at a lower pay rate than the offers I had on the the table. As such where an applicant or employee is qualified for work of any description – as I was – it shall be unlawful for such people to offer or afford the applicant or employee less favourable terms of employment, or conditions of work.
  • Contravention of part 2 section 17 of the NZ Bill of Rights Act 1990 in relation to Freedom of thought, conscience, and religion. Namely that everyone has the right to freedom of thought, conscience, religion, and belief, including the right to adopt and to hold opinions without interference.
  • The Department of Corrections was formed in 1995 with the intention of improving public safety and assisting in the rehabilitation and reintegration of offenders. Part of my rehabilitation involves fair and equal rights of access to employment.

 

My Customary Rights Claim

  • I claim that my Customary rights are infringed, as promised by article 24, clause 1 of the United Nations Declaration on The Rights of Indigeonous Peoples 2007; expressly that Indigenous peoples have the right to their traditional medicines and to maintain their health practices, including the conservation of their vital medicinal plants, animals and minerals. Indigenous individuals also have the right to access, without any discrimination, to all social and health services.
  • Establishment of own Customary rights to plant based medicine and ceremonies is presented.
  • My fathers tribe (collectively, the Xxxxxxxns, the Rixxxonxs, the Huxxxxouses) come from the United Kingdom and I claim Customary use of the plant Cannabis Sativa for use as a hemp fibre, such as that enjoyed by my forefathers did before me in the UK. I am a direct descendant by blood of Hxxxx Axxxxx Xxxxxxxn who arrived in 1852, and he is my great great great grandfather by father-son relationship. My evidence will show that the production of hemp (cannabis Sativa) was one of the prime motivators for the British colonisation of Australasia at the end of the 18th century. Britain’s economy and security was almost entirely dependent on the traditional hemp plant, Cannabis sativa. I wish to be allowed to pursue my forefathers reasons for coming to this fine land, and to be allowed my traditional methods of fibre production for linen, rope, sheets and sails and so forth.
  • My mothers tribe (the Bxxxxxs) come from Austria in 1939 seeking refuge from persecution from Hitler, and belongs to the Jewish faith. In the Shulchan Aruch (Code of Jewish Law) you can find the text that reads: “Also, one will beautify [Shabbat candle lighting] when the wick is made from cotton, flax or cannabis…”. It is clear to me that using cannabis for clothing and accessories was very common to my ancestors. It was used for making tallitot and tzitzit, as well as “schach” (Sukkot roof coverings), and cannabis fits into the category of kitnyos on Passover, meaning that Ashkenazi Jews were prohibited from using it on the holiday. One thus might assume that it was also consumed, perhaps as food, during the remainder of the year.
  • While none of these traditional purposes even include psychotropic usage, however, I do not see this as an issue, and psychotropic use can be argued as granted in our universal right to freedom of thought and religion.
  • Some members of our community feel it a matter of life and death, and in fact, and work tirelessly day and night to resolve the situation. For example, in the sad case of one late Stephen Macintyre, a generous man who was said to have supplied terminal cancer patients with below-cost medical cannabis, was needlessly persecuted by the police after a breach of his privacy, and by the same multiple warrantless searches on his home to mine, and he decided the system was in fact too strong to fight alone, to hang himself with a rope.
  • The Bill of Rights Act was cripled when passed into law as a regular statute, and therefore our judiary seem bewilderingly, and unsettlingly forced into a quite strict robotic form of the legal interpretations of the act in regards cannabis. It would appear the only body capable of full exoneration is a jury of my peers.
  • Should parliament be instructed by the supreme court to act positively and decisively on the advice of the United Nations Human Rights Commission in it’s 4th and 5th periodic reports?
  • These are about right to a fair trial and the presumption of innocence relating to possession with intent to supply. The UNHRC says that the burden of proof must fall with the prosecution, not with to the defence to prove innocence, so can we please have a direction from the supreme court on the matter?
  • Do we have no other option but to forever incarcerate recidivist cannabis growers, dealers and users who refuse to cease growing, selling, and using the plant?
  • Most recidivist criminals receive extremely long preventative detention sentences for good reason.
  • Along with the United Kingdom and Israel, New Zealand is alone in not having a written, codified constitution, but at any rate laws are actually an extremely weak guarantee of outcome. We outlaw murder, theft, they still happen. This is not to say those behaviors are not bad; and it is not to say we don’t want to have any rules or laws; but that there are better guarantees of outcomes should we choose to look at the evidence.
  • The evidence shows that ethics, morality, and a humanity are a better guarantee of desirable outcomes for a country than strict laws to enshrine a victimless crime law initially designed to target political opponents of Richard Nixon.
  • We intend to widely distribute the Jury Biasing Flyer in order to bias the jury towards nullification of this violent prohibition that has gone for long enough.
  • Should the jury and judiciary consider complex variables such as compassion, ethics, morality, and humanity or rather be instructed to instead behave more reliably like a computer, emotionless, robotic, but yet 100% fair and even entities?
  • I would like the double positive scenario (both fair and humane) affirmed by a supreme court judge, to ensure the possibility of a fair trial for my friend and myself in future. The negative-positive combination (not human but only fair) appears to be the de facto method in NZ, hence the interlocution in this case.
  • Should the judiciary and juries be instructed to overturn cases based on humanity?

 

In the District Court of New Zealand, Whangarei / Auckland / Hamilton Registry

IN THE MATTER OF THE Judicature Act 1908, Misuse of Drugs Act 1975, The Health Act 1956, Bill of Rights Act 1990, UN DRIPs 2007, Magna Carta 1215, King v Penn 1670 (Tower of London); Orders of King Henry 1533 and Elizabeth 1563; A Class Action Application For Interim Orders For A Stay Of Proceedings Pending Reclassification Of Cannabis Via Judicial Review; And Of The Failure Of The Statutory Duties Of The EACD, MOH, HRC And Office of the Queens Council to the Parliament of NZ

Crown versus Xxxxl                         CRI-2015-0X9-00XX19 (upcoming hearing 29 Sept 2016)

Crown versus Xxxxxxxn       CRI-2014-0X4-029XX; CRI-2015-0X4-0085XX; and CRI-2015-404-00X365 (sentenced 29 October 2015, high court appeal 15 December 2015)

Crown versus Citizens         class action interim injunction on behalf of 46% of NZ citizens hereby initiated

BETWEEN                         Rxxxx Xxxxxt Xxxxl, of Whangarei, Engineer Applicant
Xxxxxs Xxxxxr Xxxxxxxn, of Auckland, Professional Drummer, Website Consultant, Law Enthusiast Applicant
The Citizens of New Zealand Class Action Applicants

AND                                 Dr Keith Bedford, of Auckland, Toxicology, The Expert Advisory Committee on Drugs Respondent failure of statutory duty in Misuse of Drugs Act 1975

AND                                 Dr Chai Chuah, of Auckland, Director General Ministry of Health Respondent Section 3A Failure to adhere to the spirit of the Function of Ministry of The Health Act 1956

AND                                 David Rutherford, Chief Commissioner of the Human Rights Commission Respondent breach of the spirit of part 2 section 17 of the NZ Bill of Rights Act 1990; breach of article 24, clause 1 of the UN Declaration on The Rights of Indigeonous Peoples 2007

AND                                 Chris Finlayson Solicitor General of New Zealand Respondent general and systemic failure in parliaments poor response to UNHRC 5; Law Commission 20112; clarification of Mckenzie friend counsel T Xxxxxxxn; claim of right; jury nullifcation by direct address to jury to strike the prohibition with fresh bias and great prejudice.

Undertaking by the Applicant as to damages

 

To: The Registrar of the District Court

I, Rxxxx Xxxxl, the applicant in this proceeding, undertake that if, by reason of the granting of the order for injunction sought by the applicant, the respondants sustain any damages that in the opinion of the court the applicant ought to pay, the applicant requests, in accordance with wording of the law – to let the costs lie where they fall.

  • The costs should lie where they fall because this document if brought as a class action would likely bring over $4 billion in damages based on $400 million/year cost to government of prohibition based on the Sue Grey OIA[25].
  • Just one single year of the prohibition running in this counrty would create an easy net boost to the government coffers caused by the success of this action and is I propose likely a suitable bond against failure on my part in bringing it; in order to as is my right in the law to let the costs “lay as they fall” in the words of the law itself.

On the above basis the plaintiff seeks the following remedy:

  • Judicial Review to force removal – or replacement by the correct chemical compound names of the active ingrediants – of the plant genus Cannabis Sativa and it’s herbal extracts from schedules of the Misuse Of Drugs Act 1975.
  • Government funded study of the compounds in cannabis, including but not limited to the following compounds:

THC, THC-A, CBD, CBN, CBC, CBG, CBC and potentially about 80 other chemicals in the class of compounds known as cannabinoids and terpynes, found in abundance in the cannabis plant. Cannabinoids are responsible for many of the effects of cannabis consumption and have important therapeutic benefits.

  • Confirmation by judicial review that the defence can address the jury and be allowed the fullest chance to present a defence of jury nullification, by informing them of the history of juries in England, especially with reference to the Magna Cart 1215 and case of William Penn 1670.
  • We request that the court exercise it’s ability under the Judicature Act 1908 and issue an interim order declaring that the Crown ought not to institute or continue with any proceedings, civil or criminal, in connection with cannabis.
  • I may absolve my claim of damages arising from the inappropraite classification of cannabis, and the failure of the EACD to remove the whole plant, equal to the resultant financial, physiological and psychological hardships I’ve endured arising from these bizarre punishments that seem out of all proportion to relative seriousness of the “crimes” alleged; and resulting from the lack of access to appropriate herbal medicine; if the court or body involve would consider my claim and offer to extinguish all past convictions, drop all current cases and prosecutions, release all current prisoners, and begin to collect taxes on it.

 

Signature:                                                          (sign here)

 

 

  • In 1533 King Henry VIII decreed that all landholders set aside one-quarter acre for the cultivation of hemp for every sixty acres of land that they tilled, in order to provide the necessary fibre required by the nation. This was to satisfy the increased demand for rope and sailcloth for King Henry’s VIII new navy. In 1563 Queen Elizabeth I backed this up with a £5 fine. I put it that the United States led war on drugs was incorrectly and illegally applied in breach of these orders by the Royalty and due for immediate repeal.
  • In Magna Carta we see

 

Laws are weak guarantees of outcomes.

We outlaw murder, theft, but they still happen.

This is not to say those crimes are OK, and this is not to say that all laws are bad. But sometimes there are better alternatives.

The law is no substitute for consciousness. The legality of a thing is no guarantee of the morality of it.

Sometimes a humane approach is the right approach; we should be allowed to consider when they are appropriate, and be allowed to request the jury to consider it, not prevented from depositing this historic, scientific, and cultural evidence.

And if ethics and humanity can by fact provide greater guarantee of desired outcomes and protection of individual human rights than legislation is – then it’s that moment when the actual laws and policies themselves are left forlorn and obsolete, and they become a tool of abuse of the state, and a way to discriminate and segreate communities with violnce and promotes a culture of gang warfare.

Yours sincerely, Xxxxxs and Rxxxx.

Thursday, 29 September 2016 at the District Court of Whangarei / Auckland / Hamilton

 

PS Thank you and thanks in advance for your eagerly awaited reply! Some further information about the drugs found in the plant cannabis sativa are in my appendix. As you can see I have actually purposefully held back on the questions for my interlocution, as their is a lot more material I have not covered in Appendix B.

 

Xxm Xxxxxxxn – Director

The Xxxxxsachi Corporation

M: 021 xxxxx22 | Web:

Subscribe to Auckland Music Update

Bands: Xxxxxsachi.tv | tripxxxxxxx.com

 

 

 

 

Date:                 /           /

 

Name:             Xxxxxs Xxxxxr Xxxxxxxn

 

This document is filed by the plaintiff in person. The address for service of the plaintiff in this proceeding is

Suite 6734

PO Box 83000

Johnsonville

Wellington 6440

New Zealand

xxxxxs@legalise.org.nz

 

 

 


Appendix A – Plaintiff’s list of documents relied on

 

Next event date:                         Thursday 29 Sept 2016 Hamilton District Court
Crown versus Xxxxl      CRI-2015-0X9-00XX19 v

Filed by Xxm Xxxxxxxn, the plaintiff in person.

And; for many other persons: The Citizens of New Zealand and Rxxxx Xxxxl.

 

To the Registrar of the High Court at Whangarei / Auckland / Hamilton

and

To Dr Keith Bedford, The Expert Advisory Committee on Drugs, Dr Chai Chuah, Director General Ministry of Health, Chris Finlayson Solicitor General of New Zealand, David Rutherford, Chief Commissioner of the Human Rights Commission

Lists of the documents relied on by the plaintiff

[1]   Supreme Court Act 2003.pdf
[2]   Judicature Amendment Act 1972.pdf
[3]   eacd-meeting-minutes-27apr2016.docx
[4]   UN Declaration Righs Indigenous Peoples DRIPS_en.pdf
[5]   OIA 2015150639-0001 Alex Renton Peter Dunne 2407.pdf
[6]   Cannabinoids and Glaucoma BJO 08800708.pdf
[7]   Bove – Use of Marijuana for the treatment of Multiple Sclerosis.pdf
[8]   “Towards the use of cannabinoids as antitumour agents”

Guillermo Velasco, Cristina Sánchez & Manuel Guzmán; Nature Reviews Cancer 12, 436-444 (June 2012) | doi:10.1038/nrc3247UN Universal Human Rights 1939.pdf

[9]   Day-Cancer-Why-We’re-Still-Dying-to-Know-the-Truth-(2000).pdf
[10]          Sativex Datasheet: Potential Therapeutic Drug Interactions
[11]          LD50 cannabis Exhibit_G.pdf
[12]          “The Therapeutic Potential of Cannabis and Cannabinoids”

Grotenhermen, Franjo (23 Jul 2012). “The Therapeutic Potential of Cannabis and Cannabinoids”. Dtsch Arztebl Int. 109 (PMC3442177): 495–501. doi:10.3238/arztebl.2012.0495. PMC 3442177. PMID 23008748. Franjo Grotenhermen, Nova-Institut, Goldenbergstrasse 2, 50354 Huerth, Germany. franjo.grotenhermen@nova-institut.de

[13]          Psychoactive Substances Act 2013.pdf
[14]          UN 5th Periodic CCPR-C-NZL-CO-5.pdf
[15]          Jury Biasing Flyer.pdf
[16]          Homosexual law reform bill petittion

http://www.stuff.co.nz/national/politics/81616306/Thirty-years-on-from-NZs-tumultuous-gay-law-reform-bill

[17]          Magna Carta 1215 AD.pdf
[18]          William-Penn-and-Nullification.pdf
[19]          Waihopai Leason-2013-NZCA-509.pdf
[20]          NZHRC Decline Customary Rights February 2016
[21]          Customary Rights Claim of Xxxxxs Xxxxxr Xxxxxxxn
[22]          Crownlaw-prosecution-guidelines.pdf
[23]          Synod_Prison_Task_Group_Incarceration_in_NZ 2010.pdfMisuse of Drugs Act 1975.pdf
[24]          Misuse of Drugs Medicinal Cannabis Amendment Bill.pdf
[25]          The Emperor Wears No Clothes – Jack Herer 25.pdf
[26]          Sativex Application Approval Form.doc
[27]          Law Commission Review 2011.pdf
[28]          Inquiry-cannabis-legal-status-DBSCH-SCR-2531-2399.pdf Forty-seventh Parliament (Steve Chadwick, Chairperson) August 2003:
a.     Page 49-50 EACD give a high priority to its reconsideration of the classification of cannabis.
b.     Recommendation 22 Page 57 shows support for clinically tested cannabis products for medicinal purposes
[29]          Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. Guillermo Velasco, Complutense University, Madrid, Spain. 2009.
[30]          Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. Salazar et al. Journal of Clinical Investigation, 2009; DOI: 10.1172/JCI37948.
[31]          THC Shrinks Tumours. Munsen A.E et al. J Nat Cancer Inst, Vol 55, No. 3, Sept 1975.
[32]          Emerging Clinical Applications for Cannabis & Cannabinoids 2009

 

A 2009 review of nearly 200 scientific trials assessing the therapeutic utility of cannabinoids for the treatment of nineteen clinical indications: Alzheimer’s disease, ALS, chronic pain, diabetes mellitus, dystonia, fibromyalgia, gastrointestinal disorders, gliomas, hepatitis C, HIV, hypertension, incontinence, MRSA, multiple sclerosis, arthritis, sleep apnoea, and Tourette’s syndrome.

 

Appendix B – Excerpts of evidence

 

[1]   Supreme Court Act 2003.pdf

 

interlocutory application—

  • (a)  means an application in a proceeding or intended proceeding for—
    • (i)  an order or a direction relating to a matter of 
procedure; or
    • (ii)  in the case of a civil proceeding, for some relief 
ancillary to the relief claimed in the pleading; and
  • (b)  includes an application for a new trial; and
  • (c)  includes an application to review a decision made on an interlocutory application

 

[2]   Judicature Amendment Act 1972.pdf

 

4 Application for review

On an application which may be called an application for re­ view, the High Court may, notwithstanding any right of appeal possessed by the applicant in relation to the subject matter of the application, by order grant, in relation to the exercise, refusal to exercise, or proposed or purported exercise by any per­ son of a statutory power, any relief that the applicant would be entitled to, in any one or more of the proceedings for a writ or order of or in the nature of mandamus, prohibition, or certiorari or for a declaration or injunction, against that person in any such proceedings.

[3]   eacd-meeting-minutes-27apr2016.docx

 

Excerpts from point 5: Cannabidiol (CBD)

[redacted] (Senior Policy Analyst, MoH) and [redacted] (Principal Advisor, Medicines control) attended the meeting at 10.21am.

Dr Stewart Jessamine chaired the discussion as Assoc. Prof. Cynthia Darlington had declared a conflict of interest due to her involvement in preclinical research into cannabinoid pharmacology. The Committee had no issues with Assoc. Prof. Cynthia Darlington being present for the discussion given her expertise in the area but she would be excluded from the decision making process due to the outcome potentially impacting the regulatory environment for research.

[redacted] gave a brief contextual overview within the Ministry of Health (MoH). [redacted] has been involved in therapeutic uses of controlled drugs for the last few years, with her main area of interest recently being around medicinal cannabis. The MoH policy unit are of the understanding that Minister Dunne is comfortable around the current legal framework regarding access and use of controlled drugs, but he is interested to see if the policies and processes are as streamlined as they can be regarding patient safety and access.

The policy unit are currently doing work around medicinal cannabis classification in line with the EACD meetings consideration. [redacted] gave a brief overview of the function of Medicines Control. Medicines Control is a regulatory unit that regulate the medicines supply chain, which includes controlled drugs. The classification of medicinal cannabis has been quite topical in the last year and whatever final recommendations are made by the Committee will affect Medicines Control as they administer licences, approvals, permissions etc.

[redacted] advised that currently, if a practitioner wishes to prescribe a cannabinoid or products that contain cannabinoids, they have to make an application to the Minister. Currently there are no products containing only CBD that are approved medicines both domestically and internationally. There are however, a number of non-pharmaceutical products available. It was noted that there was a difference of opinion between ESR and MoH regarding whether or not CBD should be considered a controlled drug or not. The Therapeutic Goods Administration (TGA) in Australia have recently down-scheduled CBD to a prescription only medicine with less than two percent of other cannabinoids as most CBD extracts contain small amounts of tetrahydrocannabinol (THC) due to the difficulty and associated cost to separate the two substances. The Misuse of Drugs Act (MoDA) only requires one molecule of a controlled substance to be present in a preparation for it to be captured as a controlled drug.

There is an entry in the Medicines Regulations for CBD as a prescription medicine, however, if it is also considered a controlled drug, then MoDA acts as the dominant piece of legislation.

The technical paper looked at the potential therapeutic effects of CBD in comparison to the abuse potential. The Committee had been asked to determine whether or not there was sufficient evidence to make a recommendation for de-scheduling CBD from being captured under MoDA so that it is classified as a prescription medicine only. The Committee was also asked to consider an amendment allowing CBD preparations to contatin THC and other cannabinoids found in cannabis up to a certain threshold to enable the de-scheduling of CBD to take effect. The Committee considered the options for streamlining medical access to CBD as a controlled drug.

[redacted] advised that there were some controlled drugs that had been exempted from the ministerial approval requirements process as they had been specifically named as exempt as medicines under the Misuse of Drugs Regulations. Blanket or general approvals, permissible under Regulation 22 of the Misuse of Drugs Regulations, have also been issued to supply prescribe and administer certain controlled substances . There are multiple avenues that could be considered with regard to what mechanisms are available to streamline the process to access CBD based medicines, however, the main driver for the reclassification of CBD is the TGA decision because they have set a new approach to cannabinoid based medicines.

[redacted] spoke to the notes submitted by [redacted] which covered a few issues with the current legislation. [redacted] also advised that although CBD does have the same molecular formula, ESR do not consider CBD as an isomer of THC within the specific chemical designation under MoDA as CBD is significantly different in structure from THC and is not explicitly named under the legislation. ESR also do a lot of testing for hemp growers who have expressed interest in information regarding CBD content of hemp plants and hemp fibre for therapeutic use. Another point of consideration is that more clarification around what is considered the definition of medicinal cannabis is needed.

Research in this area can be difficult due to the bureaucratic layers to obtain permission. Moving CBD out of MoDA would remove those controls but would still need to address the THC component of the argument as THC is specifically named as a controlled drug under MoDA. More research is required regarding the potential associated risks, however, the risk of CBD causing psychoactive harm is very low as CBD on its own does not produce psychoactive effects. It was also noted that approved prescription medicines have to meet quite stringent requirements regarding controls around dosage, concentration and stability among other testing criteria.

 

Currently, under section 29 of the Medicines Act 1981, there is an exemption for medical practitioners to prescribe unapproved medicines. Non-pharmaceutical forms do not need to meet the same requirements as approved prescription medicines.

MoH considers that CBD, even in the absence of THC, is a controlled drug under the isomer provisions of MoDA and it has administered the Medicines and Misuse of Drugs Acts in accordance with this view. If CBD is de-scheduled from MoDA to be a prescription medicine only, prescriptions will still be required to be in possession of CBD. There was a discussion around what the potential implications would be for de-scheduling CBD regarding over prescribing and abuse. Though CBD can be converted to THC, abuse and conversion of CBD to THC is considered unlikely as CBD based medicines would most likely cost much more than buying cannabis off the street as well as having to go through the process of gaining a prescription to access the CBD medicine. Currently, individuals can carry on their person up to a month’s supply of controlled drugs into NZ with appropriate overseas prescriptions and proof that it was lawfully supplied overseas for the purpose of treating a medical condition..

To address the issue around THC content in CBD medicines, it was suggested that a THC content threshold be set, similar to the allowable threshold of THC in hemp. It was discussed if the limit should be two percent, in line with Australia, or 0.35 percent in line with the threshold for THC in hemp.

The Committee queried whether there was enough evidence presented to make a recommendation for an allowable THC threshold in CBD preparations. They were particularly interested in the processes that led to the 0.35 percent threshold of THC allowed in hemp in NZ and the two percent threshold of other cannabinoids allowed in CBD medicines in Australia. The question was also raised of what the THC content of cannabis generally is.

Outcome: The Committee deferred the decision to the next meeting as more information is needed regarding the process that lead to the 0.35 percent of THC content threshold being allowed in hemp and the two percent threshold of other cannabinoids allowed in CBD medicines in Australia. Research around the effects of consumption of two percent of additional cannabinoids in a CBD product also needs to be looked at by the Secretariat and brought to the Committee.

Action: Secretariat to find out the process that lead to the 0.35 percent threshold of THC content allowed in hemp and report back to the Committee.

Action: Secretariat to find out what the process was for the TGA reaching the two percent threshold of other cannabinoids allowed in CBD medicines.

Action: Secretariat to find out more information around concentration levels of THC in the average cannabis that is circulating in the NZ market.

Action: Secretariat to find out more information regarding effects of consumption of products containing different concentrations of THC.

Action: Secretariat to add CBD to the next agenda.

[redacted] and [redacted] left the meeting at 12.04pm

 

[4]   UN Declaration Righs Indigenous Peoples DRIPS_en.pdf
[5]   OIA 2015150639-0001 Alex Renton Peter Dunne 2407.pdf

 

[6]   Cannabinoids and Glaucoma BJO 08800708.pdf

 

 

 

 

[7]   Bove – Use of Marijuana for the treatment of Multiple Sclerosis.pdf
[8]   “Towards the use of cannabinoids as antitumour agents”

Guillermo Velasco, Cristina Sánchez & Manuel Guzmán; Nature Reviews Cancer 12, 436-444 (June 2012) | doi:10.1038/nrc3247UN Universal Human Rights 1939.pdf

[9]   Day-Cancer-Why-We’re-Still-Dying-to-Know-the-Truth-(2000).pdf
[10]          Sativex Datasheet: Potential Therapeutic Drug Interactions
[11]          LD50 cannabis Exhibit_G.pdf
[12]          “The Therapeutic Potential of Cannabis and Cannabinoids”

Grotenhermen, Franjo (23 Jul 2012). “The Therapeutic Potential of Cannabis and Cannabinoids”. Dtsch Arztebl Int. 109 (PMC3442177): 495–501. doi:10.3238/arztebl.2012.0495. PMC 3442177. PMID 23008748. Franjo Grotenhermen, Nova-Institut, Goldenbergstrasse 2, 50354 Huerth, Germany. franjo.grotenhermen@nova-institut.de

[13]          Psychoactive Substances Act 2013.pdf
[14]          UN 5th Periodic CCPR-C-NZL-CO-5.pdf
[15]          Jury Biasing Flyer.pdf
[16]          Homosexual law reform bill petittion

http://www.stuff.co.nz/national/politics/81616306/Thirty-years-on-from-NZs-tumultuous-gay-law-reform-bill

[17]          Magna Carta 1215 AD.pdf
[18]          William-Penn-and-Nullification.pdf
[19]          Waihopai Leason-2013-NZCA-509.pdf
[20]          NZHRC Decline Customary Rights February 2016
[21]          Customary Rights Claim of Xxxxxs Xxxxxr Xxxxxxxn
[22]          Crownlaw-prosecution-guidelines.pdf
[23]          Synod_Prison_Task_Group_Incarceration_in_NZ 2010.pdfMisuse of Drugs Act 1975.pdf
[24]          Misuse of Drugs Medicinal Cannabis Amendment Bill.pdf
[25]          The Emperor Wears No Clothes – Jack Herer 25.pdf
[26]          Sativex Application Approval Form.doc
[27]          Law Commission Review 2011.pdf
[28]          Inquiry-cannabis-legal-status-DBSCH-SCR-2531-2399.pdf Forty-seventh Parliament (Steve Chadwick, Chairperson) August 2003:
a.     Page 49-50 EACD give a high priority to its reconsideration of the classification of cannabis.
b.     Recommendation 22 Page 57 shows support for clinically tested cannabis products for medicinal purposes
[29]          Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. Guillermo Velasco, Complutense University, Madrid, Spain. 2009.
[30]          Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. Salazar et al. Journal of Clinical Investigation, 2009; DOI: 10.1172/JCI37948.
[31]          THC Shrinks Tumours. Munsen A.E et al. J Nat Cancer Inst, Vol 55, No. 3, Sept 1975.
[32]          Emerging Clinical Applications for Cannabis & Cannabinoids 2009

 

A 2009 review of nearly 200 scientific trials assessing the therapeutic utility of cannabinoids for the treatment of nineteen clinical indications: Alzheimer’s disease, ALS, chronic pain, diabetes mellitus, dystonia, fibromyalgia, gastrointestinal disorders, gliomas, hepatitis C, HIV, hypertension, incontinence, MRSA, multiple sclerosis, arthritis, sleep apnoea, and Tourette’s syndrome.

 

 

Pharmacologically active chemical compounds Cannabis

 

THC, THC-A, CBD, CBN, CBC, CBG, CBC and about 80 other chemicals are all in a class of compounds known as cannabinoids, found in abundance in the cannabis plant. Cannabinoids are responsible for many of the effects of cannabis consumption and have important therapeutic benefits.

Delta-9-Tetrahydrocannabinol or (THC) is a psychoactive cannabinoid responsible for many of the effects experienced by the cannabis user.
Mild to moderate pain relief, relaxation, insomnia and appetite stimulation.
THC has been demonstrated to have anti-depressant effects.
The majority of strains range from 12-21% THC with very potent and carefully prepared strains reaching even higher. Average THC potency is about 16-17% in Northern CA.
Recent research that suggests patients with a pre-disposition to schizophrenia and anxiety disorders should avoid high-THC cannabis. Cannabidiol or (CBD) occurs in many strains, at low levels, <1%.   In rare cases, CBD can be the dominant cannabinoid, as high as 15% by weight. Popular CBD-rich strains (>4% CBD) include Sour Tsunami, Harlequin and Cannatonic.

It can provide relief for chronic pain due to muscle spasticity, convulsions and
inflammation. Offering relief for patients with MS, Fibromyalgia and Epilepsy.
Some researchers feel it provides effective relief from anxiety-related disorders.
CBD has also been shown to inhibit cancer cell growth when injected into breast and brain tumors in combination with THC.
Cannabinol or (CBN) is an oxidative degradation product of THC. It may result from improper storage or curing and extensive processing, such as when making concentrates. It is usually formed when THC is exposed to UV light and oxygen over time.

CBN has some psychoactive properties, about 10% of the strength of THC.
CBN is thought by researchers to enhance the dizziness and disorientation users of cannabis may experience.
It may cause feelings of grogginess and has been shown to reduce heart rate.
Cannabichromene or (CBC) is a rare, non-psychoactive cannabinoid, usually found at low levels (<1%) when present.

Research conducted has shown CBC has antidepressant effects, 10x those of CBD.
CBC has also been shown to improve the pain-relieving effects of THC.
Studies have demonstrated that CBC has sedative effects, promoting relaxation.
Cannabigerol or (CBG) is a non-psychoactive cannabinoid. It is commonly found in cannabis. CBG-acid is the precursor to both THC-acid and CBD-acid in the plant usually found at low levels (<1%) when present.

Researchers have demonstrated both pain relieving and inflammation reducing effects.
CBG reduces intraocular pressure, associated with glaucoma.
CBG has been shown to have antibiotic properties and to inhibit platelet aggregation, which slows the rate of blood clotting.

 

CBC has been shown to increase the viability of progenitor (stem) cells in the brains of mammals, and is therefore likely to be a form of brain growth stimulant.

 

Terpenes are a diverse range of hydrocarbons that make up the smell constituents of cannabis. The sense of olfaction was the first sense to evolve in animals and eukaryotic multi-celled organisms, and the olfactory senses are those closest to the brain.

 

 


NZHRC Decline Customary Rights February 2016

 

Case ID: 110054

Good morning Xxxxxs Xxxxxxxn,

Thank you for your emails of 17 & 18 February 2016.

You are complaining that you have been discriminated against on the grounds of ethical belief, religious belief, and political opinion due to being unable to use cannabis sativa, indica and ruderalis for medicinal and therapeutic use. You also contend that the inability to use cannabis sativa, indica and ruderalis contravenes the right to freedom of thought, conscience and religion, affirmed in section 13 of the New Zealand Bill of Rights Act.

In addition, you complain that that the inability to use cannabis sativa, indica and ruderalis also contravenes Article 24(1) of the UN Declaration on the Rights of Indigenous Peoples which sets out Indigenous peoples have the right to their traditional medicines and to maintain their health practices, including the conservation of their vital medicinal plants, animals and minerals.

You set out your linkage to Indigenous peoples as being on your father’s side, emigrants from the UK who arrived in NZ in 1852, and on your mother’s side, her being a Jewish refugee from Austria who arrived in NZ in 1939.

You also ask how you can best establish your Customary right to plant based employment, medicine and freedom of thought and the right to develop your consciousness and personality as a European citizen of NZ.

Your suggested remedy is that the HRC and the ACLC seek an injunction removing cannabis from the Schedules to the Misuse of Drugs Act.

There is no indicator in the information provided by you that the matters you complain about could arguably amount to unlawful discrimination in breach of the Human Rights Act.

The Commission will take no further action in relation to this matter.

Kind regards,

 

Robert Hallowell

Legal Counsel

roberth@hrc.co.nz


Appendix B of Misc. Evidence

Minister Peter Dunne approves one-off use of Cannabidiol product ‘Elixinol’

 

9 June 2015 Beehive Press Release https://www.beehive.govt.nz/release/minister-approves-one-use-cannabidiol-product-%E2%80%98elixinol%E2%80%99

Associate Minister of Health Hon Peter Dunne has today approved on compassionate grounds the one-off use of Elixinol, a cannabidiol (CBD) product from the United States to be administered by clinicians treating Wellington patient Alex Renton.

“I have also considered the absence of any other treatment options, the low risk of significant adverse effects, and the conclusion reached by the hospital ethics committee from an individual patient perspective.”

 


Sativex Datasheet: Potential Therapeutic Drug Interactions

 

Sativex Datasheet: Potential Therapeutic Drug Interactions (this a guide and not meant to be exhaustive)
               Concomitant Drug Clinical effect
Amphetamines, cocaine, other sympathomimetic agents Additive hypertension, tachycardia, possibly cardiotoxicity
Atropine, hyoscine (scopolamine), antihistamines, other anti-muscarinics Additive or super-additive tachycardia, hypertension, enhancement of sedation and pain reduction
Amitriptyline, amoxapine, desipramine, other tricyclic antidepressants Additive tachycardia and hypertension. Sedating effects may be enhanced
Anti-depressants (SSRIs): fluoxetine etc THC may increase the effect of SSRIs. Hypomanic reaction reported with smoking cannabis
Alcohol Increase in the positive subjective mood effects of smoked cannabis. Additive drowsiness and CNS depression
Barbiturates Decreased clearance of these agents, presumably via competitive inhibition of metabolism. Additive drowsiness and CNS depression
Benzodiazepines

 

Respiratory depression and depression of the brain function may be increased. The antiepileptic action may be enhanced.
Disulfiram Reversible hypomanic reaction reported with smoking cannabis
Naltrexone THC effects are enhanced by opioid receptor blockade
Neuroleptics THC may antagonize the antipsychotic actions of neuroleptics. It may improve their therapeutic effects in motor disorders
Non steroidal anti-inflammatory drugs (NSAID)

 

Indomethacin, acetylsalicylic acid (aspirin), and other NSAIDs antagonise THC effects. Indomethacin significantly reduced subjective “high” and acceleration of heart frequency
Opioids Enhancement of sedation and pain reduction. Cross-tolerance and mutual potentiation. CNS depression & drowsiness
Phenothiazines (anti-psychotics/ anti-emetics) Attenuates the psychotropic effects of THC and increases anti-emetic effects
Theophylline Increased theophylline metabolism reported with smoking cannabis, effect similar to that following smoking tobacco

Sativex® (Datasheet) GW Pharmaceuticals Ltd. UK; 2006 http://www.gwpharma.co.uk/sativex.asp

 

Supreme Court Act 2003

 

 

 

In The Public Interest

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Signature of plaintiff

 

 

                                                                                                (sign here)

 

 

Full name and address: Xxxxxs Xxxxxr Xxxxxxxn

XX Xexxxnt St
Xoxxonxy
Auckland
Date:

29/12/16

 

 

 

 

 

 

 

 

 

 

[1]
Statement of claim

[2] The plant name Cannabis is from Greek κάνναβις (kánnabis), via Latin cannabis,[1] originally a Scythian or Thracian word,[2] also loaned into Persian as kanab. English hemp (Old English hænep) may be an early loan (predating Grimm’s Law) from the same Scythian source.

[3] Supreme Court Act 2003.pdf

[4] Judicature Amendment Act 1972

[5] Judicature Amendment Act 1908

[6] Error! Reference source not found.

[7] UN Declaration Righs Indigenous Peoples DRIPS_en.pdf

[8] OIA 2015150639-0001 Alex Renton Peter Dunne 2407.pdf

[9] Error! Reference source not found.

[10] Error! Reference source not found.

[11] Error! Reference source not found.

[12] Error! Reference source not found.

[13] Error! Reference source not found.

[14] Error! Reference source not found.

[15] “The Therapeutic Potential of Cannabis and Cannabinoids”. Dtsch Arztebl Int. 109 (PMC3442177): 495–501. doi:10.3238/arztebl.2012.0495. PMC 3442177free to read. PMID 23008748. Franjo Grotenhermen, Nova-Institut, Goldenbergstrasse 2, 50354 Huerth, Germany. E-mail: franjo.grotenhermen@nova-institut.de

[16] Error! Reference source not found.

[17] Error! Reference source not found.

[18] Error! Reference source not found.

[19] Petition delivered to parliament in regards the homosexual law reform bill http://www.stuff.co.nz/national/politics/81616306/Thirty-years-on-from-NZs-tumultuous-gay-law-reform-bill

[20] Error! Reference source not found.

[21] Error! Reference source not found.

[22] Error! Reference source not found.

[23] Law Commission Review 2011.pdf

[24] Error! Reference source not found.

[25] OIA 20160197 Sue Grey – Economic Cost of Prohibition.pdf



Time to rark up the government, tired of waiting, been long enough now…

To: “supremecourt@justice.govt.nz” <supremecourt@justice.govt.nz>

CC: info@cannabis.org.nz, john.tulloch@parliament.govt.nz, “High Court, Auckland” <AucklandHC@justice.govt.nz>, auckland.dc@justice.govt.nz,rotorua.dc@justice.govt.nz, Parliament NZ <parlinfo@parliament.govt.nz>, Parliament NZ <speakers.office@parliament.govt.nz>, LegaliseWeedNZ <john@legalise.org.nz>, Chris Fowlie <chris@hempstore.co.nz>, Julian Crawford <julian@cannabis.org.nz>, Jarom Keung <jarom.keung@pds.govt.nz>, Ataraiti Whyte <AtaraitiW@hrc.co.nz>, Jenni <jenni@aclc.org.nz>, Supreme Court NZ <officeofthechiefjustice@justice.govt.nz>, hamilton.dc@justice.govt.nz, Alica Burrow <alicia.burrow@nzme.co.nz>, Helen Broome <helen@aclc.org.nz>, cynthia.darlington@otago.ac.nz, ESR.ExternalEnquiries@esr.cri.nz, keith.bedford@esr.cri.nz,helen.moriarty@otago.ac.nz, lynette.k@carenz.co.nz, askmedsafe@moh.govt.nz, jamie.bamford@customs.govt.nz, info@health.govt.nz, p.dunne@ministers.govt.nz, Damien O’Connor <damienoconnor@xtra.co.nz>, chai_chuah@moh.govt.nz, j.coleman@ministers.govt.nz, 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Philip.Twyford@parliament.govt.nz, Louise.Upston@parliament.govt.nz,Nicky.Wagner@parliament.govt.nz, Louisa.Wall@parliament.govt.nz, Meka.Whaitiri@parliament.govt.nz, poto.williams@parliament.govt.nz,Maurice.Williamson@parliament.govt.nz, Michael.Woodhouse@parliament.govt.nz, Megan Woods <Megan.Woods@parliament.govt.nz>, Jian.Yang@parliament.govt.nz,Jonathan.Young@parliament.govt.nz

BCC: Nick Wright, Jeremy Bioletti, Pure Analytics.net, John Wilson, Jan, Bomber, Mitch Busdriver Native, Seala, Geeksunited, Andy Tonegreen, Rust In Space, Ben Brixton, Ben The@Symbol, SWF, BlKMN, Emmeline, Jerome ‘Trumpet’, Kara on gat, Kat Styling, Kiri Anahera, ‘Monza’, Nick Supergroove, Paaka, Penny, Richard Republic, Seala, AtkinsonAAA, Kp26, Alicia Burrow, Fiona Connor

 

To The Supreme Court of New Zealand I primarily direct this email in the To: field.

 

To those in the CC: field should take note of my application and duly consider it, especially the Hamilton and Auckland district courts, the EACD, and the minister of Health.

 

A substantial portion of the recipients are hidden in the BCC: field of this email to maintain their privacy.

 

Notice is given. An email shall be sent after this revealing the hidden name CRI and date of birth numbers.


An Urgent Interlocutory Application at The Supreme Court

I, Txxxxxs Bxxxxx Axxxxxxx, of Pxxxxxxx, Auckland, 39 years of age (xx/xx/1977) hereby wish to make this formal application for an emergency interlocutory with a crown representative and a member of the EACD before 1 September 2016, the date of another person’s trial, also in relation to, but not limited to the following past and future court actions:

  1. an upcoming proceeding in the Hamilton district court (Crown v TXXXL CRI-2015-XX-XXX519)  set down for Thursday 1 September 2016
  2. my own personal application for Habeas Corpus to overturn my conviction and sentence, which were dismissed at the High Court on 15 December 2015 (CRI-2014-XX-XXX950 and CRI-2015-004-008549)
  3. A class action lawsuit I’m preparing against the government on behalf of the 400,000 people in New Zealand whom have tried the prohibited cannabis once in their lives

 

I hereby seek an urgent interlocutory order or a direction relating to a matter of procedure;

subject to the Supreme Court Act 2003.

 

The matter of procedure relates to ambiguity in the text of the law, the inheritance of laws from England, the interpretation of the meaning / purpose of a jury, inaccuracies in the text of laws, some constitutional issues, the rights of the indigenous etc:

 

[1] In the context of the Misuse of drugs act, what exactly is a drug?

 

It would seem obvious however I thought it a good place to set the context for the interrogatory please. The answer we’d assume is that a “drug” is considered for the purposes of the misuse of drugs act 1975 to be:

  1. an element or compound that affects the body in a clinically recognised and repeatable manner, but not for example a particular unique genus or specimen of a plant individual or group of plants as is the aberrant case of cannabis sativa, which is not something reproducible in a clinical trial.
  2. Cannabis sativa inclusion in the schedules is unique due to this fact since it is not a drug it is a plant
  3. No other banned or prohibited plants exist; certain noxious weeds can not be sold at garden stores, but it is not prohibited to possess or cultivate them.

 

If this basic definition is true, then the plant genus cannabis needs to be struck out of the act in this case or by amendment, and we suggest the same or intended effect could be discovered by studying the following compounds:

THC – Delta-9 Tetrahydrocannabinol, THCA – Tetrahydrocannabinolic Acid, THCV – Tetrahydrocannabivarin, CBD – Cannabidiol, CBN – Cannabinol, CBG – Cannabigerol, CBC – Cannabichromene, Terpenes – diverse group of organic HydroCarbons (C5H8).

 

[2] Do the citizens of New Zealand have the right to freedom of thought or not?

 

[3] Does the state recognise or deny our right to the freedom to develop our own unique human personality, our cultural behaviors, lifestyles, religions, traits and customs, so long as it does not harm ourselves physically or mentally, nor anyone else or nor anyone or other nation states property in any measureable way that’s reasonable?

 

Recently the Mexican supreme court ruled in favour of the right to develop a personality and stuck down the ban on the cannabis plant for contravening this, so I felt this was relevant to my interlocutory application at the Supreme Court.

 

[4] What justification exists or why should New Zealand citizens have a right to a trial by a jury of one’s peers and is this right enshrined in any legislation currently?

 

[5] Does the court agree that one good purpose of a jury is to protect citizens from overzealous governments and courts by forming a safety valve or sorts for aberrant or obsolete laws?

 

Our nation and many others are based on the universal and historic text of the Magna Carta of 1215 AD which establishes this.

 

[6] Should the criminal defence be allowed to instruct juries of their conceptual civic responsibility to deliver justice to their fellow citizens perhaps over and above the duty to law and to the crown?

 

The relevance is that we wish to mount a defence that depends on our ability to educate on history or law and instruct the jury in this case to strike out the relevant laws, Misuse of drugs act in this case, but regardless any obstruction to our natural defence this would seem to counter to the entire reason for having jury trials at all?

 

[7] Is New Zealand subject to relevant UK court precedents sovereign and UK where acquittal was provided to the accused despite considerable evidence of their “thought crimes”?

 

The cases are:

  1. a) The King v William Penn and Mead. 1670 Tower of London, United Kingdom;
  2. b) The Crown v Murnane 2008; Waihopai, New Zealand.

 

[8] Does the jury have the responsibility to deliver moral justice to the accused by acquittal from law but not guilt?

 

[9] Does the jury have the option to find any defendant not guilty even if doing so may require accepting the evidence of the crime as factually committed by the accused and yet also simultaneously determine the law itself to be invalid, irrelevant, obsolete, or not in the public interest in this particular case?

 

For example, the accused made a confession to guilt, ed his crime of thinking about it, could

if it is in direct contravention of the fact the accused was in wording of the thought crime law? (Which is the job of the police is it not?)

 

[10] Is it sensible or responsible for crown prosecution to proceed with CRI-2015-019-005519 if the defendant is indicating support from myself to mount a defence of a claim of right under the Crimes Act 1961 or should parliament intervene to clarify its position on the matter?

 

Considering the mountain of evidence against my friend (CRI-2015), and guilty admission in statements to police, an entire jury trial seems an expesive waste of tax payers money.

 

The fact that an accused person acted without “claim of right” is an element of certain offences with must be proved by the prosecution beyond reasonable doubt. It enables a defendant to advance at their trial that they genuinely believe that what they were doing was lawful, regardless of the reasonableness of that belief.

 

In summing up the case to jurors, Judge Stephen Harrop said if the Waihopai Three* believed they were acting lawfully, even if they were mistaken in that belief, they must be acquitted. The right of defence was that they acted urgently to save another life.

 

[11] Should parliament be instructed by the supreme court to act positively and decisively on the advice of the United Nations Human Rights Commission in it’s 4th and 5th periodic reports?

 

These are about right to a fair trial and the presumption of innocence relating to possession with intent to supply. The UNHRC says that the burden of proof must fall with the prosecution, not with to the defence to prove innocence, so can we please have a direction from the supreme court on the matter?

 

[12] Do we have no other option but to forever incarcerate recidivist cannabis growers, dealers and users who refuse to cease growing, selling, and using the plant?

 

Most recidivist criminals receive extremely long preventative detention sentences for good reason.

 

Along with the United Kingdom and Israel, New Zealand is alone in not having a written, codified constitution, but at any rate laws are actually an extremely weak guarantee of outcome. We outlaw murder, theft, they still happen. This is not to say those behaviors are not bad; and it is not to say we don’t want to have any rules or laws; but that there are better guarantees of outcomes should we choose to look at the evidence.

 

The evidence shows that ethics, morality, and a humanity are a better guarantee of desirable outcomes for a country than strict laws to enshrine a victimless crime law initially designed to target political opponents of Richard Nixon.

[13] Should the jury and judiciary consider complex variables such as compassion, ethics, morality, and humanity or rather be instructed to instead behave more reliably like a computer, emotionless, robotic, but yet 100% fair and even entities?

 

Possibly a combination of the two is my guess so I seek clarification.

 

I would like the double positive scenario (both fair and humane) affirmed by a supreme court judge, to ensure the possibility of a fair trial for my friend and myself in future. The negative-positive combination (not human but only fair) appears to be the de facto method in NZ, hence the interlocution here.

 

[14] Should the judiciary and juries be instructed to overturn laws based on humanity?

 

It is not outside the boundaries of imagination to say that sometimes a humane approach is the right approach; thus the law in error.

 

And we should be allowed to consider when they are appropriate.

And when humanity can in fact provide greater enforcement for individual human rights than the actual laws – the laws and policies themselves are left forlorn and obsolete.

 

Law is no substitute for consciousness.

 

The legality of a thing is no guarantee of the morality of it.

 

Yours sincerely, Tom.

 

PS Thank you and thanks in advance for your eagerly awaited reply! Some further information about the drugs found in the plant cannabis sativa are in my appendix. As you can see I have actually purposefully held back on the questions for my interlocution, as their is a lot more material I have not covered in Appendix B.  

 

Director

TC0rp

____________________________________

____________________________________

Bands: tomachi.tv | triptonites.com

 

Appendix A – Chemical Compounds

Useful Information Relating To The Plant Genus Cannabis

 

THC, CBD, CBN, CBC, CBG, CBC and about 80 other chemicals are all in a class of compounds known as cannabinoids, found in abundance in the cannabis plant.  Cannabinoids are responsible for many of the effects of cannabis consumption and have important therapeutic benefits.

Delta-9-Tetrahydrocannabinol or (THC) is a psychoactive cannabinoid responsible for many of the effects experienced by the cannabis user.

Mild to moderate pain relief, relaxation, insomnia and appetite stimulation.
THC has been demonstrated to have anti-depressant effects.
The majority of strains range from 12-21% THC with very potent and carefully prepared strains reaching even higher.
Average THC potency is about 16-17% in Northern CA.
Recent research that suggests patients with a pre-disposition to schizophrenia and anxiety disorders should avoid high-THC cannabis.
Cannabidiol or (CBD) occurs in many strains, at low levels, <1%.  In rare cases, CBD can be the dominant cannabinoid, as high as 15% by weight. Popular CBD-rich strains (>4% CBD) include Sour Tsunami, Harlequin and Cannatonic.

It can provide relief for chronic pain due to muscle spasticity, convulsions and
inflammation.  Offering relief for patients with MS, Fibromyalgia and Epilepsy.
Some researchers feel it provides effective relief from anxiety-related disorders.
CBD has also been shown to inhibit cancer cell growth when injected into breast and brain tumors in combination with THC.
Cannabinol or (CBN) is an oxidative degradation product of THC. It may result from improper storage or curing and extensive processing, such as when making concentrates.  It is usually formed when THC is exposed to UV light and oxygen over time.

CBN has some psychoactive properties, about 10% of the strength of THC.
CBN is thought by researchers to enhance the dizziness and disorientation users of cannabis may experience.
It may cause feelings of grogginess and has been shown to reduce heart rate.
Cannabichromene or (CBC) is a rare, non-psychoactive cannabinoid, usually found at low levels (<1%) when present.

Research conducted has shown CBC has antidepressant effects, 10x those of CBD.
CBC has also been shown to improve the pain-relieving effects of THC.
Studies have demonstrated that CBC has sedative effects, promoting relaxation.
Cannabigerol or (CBG) is a non-psychoactive cannabinoid.  It is commonly found in cannabis. CBG-acid is the precursor to both THC-acid and CBD-acid in the plant usually found at low levels (<1%) when present.

Researchers have demonstrated both pain relieving and inflammation reducing effects.
CBG reduces intraocular pressure, associated with glaucoma.
CBG has been shown to have antibiotic properties and to inhibit platelet aggregation, which slows the rate of blood clotting.

 

CBC has been shown to increase the viability of progenitor (stem) cells in the brains of mammals, and is therefore likely to be a form of brain growth stimulant.

 

Appendix B Open Letter to the EACD

 

[Skip to Open Letter To The EACD]

Pouring through the law books trying to find out why and how MODA 1975 got passed, and discovered we can blame Nixon. Ironically, like the TPPA, the US based changes pushed by Nixon were never actually implemented by the USA but were implemented by our 37th Parliament without any public consultation or approval.

Nixon shows he hates jews and pot... and psychiatrists?!

Nixon shows he hates jews and pot… and psychiatrists?!

Supposed to be in control of the schedules of the Misuse of drugs act, but appear to be failing in their duties:

I hereby request to them to remove the cannabis plant and natural extracts and concentrates from the schedules, perhaps with a 1 or 2 year delay on the execution so give time to draft other regulations.

As their website says, the drug classification process is based on risk of harm to individuals or society, therefore The EACD is required to advise the Minister of Health on a range of specific criteria for each drug.

  • the likelihood or evidence of drug abuse, including such matters as the prevalence of the drug, levels of consumption, drug seizure trends, and the potential appeal to vulnerable populations
  • the specific effects of the drug, including pharmacological, psychoactive, and toxicological effects
  • the risks, if any, to public health
  • the therapeutic value of the drug, if any
  • the potential for use of the drug to cause death
  • the ability of the drug to create physical or psychological dependence
  • the international classification and experience of the drug in other jurisdictions
  • any other matters that the Minister considers relevant.

More information on the criteria for classifying drugs, the role of the EACD and the Minister of Health, and the classification process is contained in sections 3A to 5AA of the Act. Go to the Misuse of Drugs Act 1975 on the New Zealand Legislation website to learn more.

So far this body has only appears to have commented on the following drugs / compounds:

Existing EACD advice to the Minister of Health

So far the body has produced reports about the following drugs of abuse:

Why is it I don’t see cannabis or extracts anywhere in this list? Well perhaps I shall give them all a ring and double check they have recommended cannabis to be removed from the schedules: at least so we can do scientific studies on it and to remove the contradiction!

Vickie appears a bit flaky (4:50 in) I think she should grow some balls and stand up us oppressed tokers by saying how sweet the mary-jane is:

She is good but I’d correct her on the “gateway drug” thing. The Prohibition is the gateway, not cannabis. If you can’t buy crack at your local bar or pharmacist, then you won’t be able to either at your cannabis dispensary.

So here is my open letter to them…

Open Letter To The EACD

Dear [EACD members name],

my name is Tom Atkinson aka Tomachi. I’m an international musician and computer artist.

I’m writing to you urgently on a matter of life and death.

Mine. But also others.

I was almost killed while spending 4 nights in Mount Eden Remand Prison over the New Years public holiday, all thanks to what I can only assume is your apparent status-quo stance on the violence-promoting prohibition of cannabis. The charges were later dropped.

I also want to apply for approval to study and begin building high powered better-than-graphene hemp batteries, and the effects of it on the mind using an OpenBCI brain scanner, but I can’t with the current appearance of cannabis in the schedules of the misuse of drugs, thanks to your lack of action in a way. I request that you remove it entirely from the schedules, thereby forcing further regulation, and showing your personal strength and the power of your science committee.

Our bill of rights was originally designed as supreme legislation back in the 1980’s. But due to the perceived threat of “judicial activism”, it was passed into law in 1990 just as a regular statute. The UN has criticised our lack of constitutional human rights twice, in the fourth and fifth periodic world report on human rights! The difference, as I understand it, meant that judges in the High Court could not decide on their own volition – called judicial activism – to override any strange obsolete law based on it’s incompatibility with the bill of human rights for example. You know such petty issues such as not to be subjected to undue search and seizure, to have some kind of privacy in your own home so long as you harm no one, not to be tortured for no good reason, and to be able to practise your religion unhindered. Oh and to be provided with justice. Those types of things**.

I was tortured for a crime that involves nobody else and a dried plant.

I was tortured purely based on my religion and thoughts: Cantheism.

I wasn’t even home when the police visited, smelt my neighbour smoking cannabis, then proceeded to kick down every door in the house of 6 people living in it doing massive damage that I am still to this day repairing, all to find 1 gram of cannabis in my bedroom? Another 2 nights in MERC on charges that were later dropped during an open court plea bargain, that only would have happened because I plead Not Guilty and asked for a full jury trial.

It’s actually becoming clear to me, that there is some pretty gross abuses of human rights perpetrated by the police around this subject. Two high end studies* I found showed systemic abuse of Maori around the issue of cannabis and it’s lax interpretation by the police. This forms part of a high court injunction I am preparing to serve against you and your committee presently to attempt to force an action.

The NIH just published a study*** showing 45% reduction in bladder cancer from the people who only consumed cannabis and not tobacco. If you can’t see this obvious promise staring you in the face, then you are failing in your duty.

Shortly I intend to apply for an injunction that forces your body – the EACD – to either a) promise to provide scientific recommendations not just on cannabis sativa, but on all medicinal natural extracts including water or b) remove cannabis sativa from the schedules due to it’s medicinal qualities and it’s natural whole-plant nature.

I also plan to, based on your response to this email and phone campaign, to potentially bring a private prosecution against you if I feel you are not cognisant of aforementioned points, for failure to perform your statutory duty. Sorry. It is your job to be cognisant, as you are the expert committee!

Perhaps you’ll need to put out three studies on the pure forms of:

  • THC for cancer prevention
  • CBD for severe epilepsy
  • CBC for brain growth stimulant

If you think about it, The Health Act 1956 binds the crown to do good, or as they say in that funky legal speak “the Ministry shall have the function of improving, promoting, and protecting public health.”

Kawa Kawa (Macropiper excelsum) is an indigenous whole plant based herb. The Maori shamans were banned I assume from using it in the Tohunga Suppression Act 1908, an act that was designed to screw over a man who goes by the name Rua Kenana. They never used it against him, only one brother got hit by that oppression in the end, but it had a chilling effect, and was repealed in the 1950’s or thereabouts, through an amendment.

I mention Kawakawa because it’s a whole plant medicine.

You can’t ban Oranges just because they contain vitamin C, and you haven’t yet put out an advisory on vitamin C yet. You never will, the industry seems to hate vitamin C. It’s a natural medicine so it’s difficult for us to figure out. The Swiss seem to have a good medical system that can do it.

When our 37th parliament passed the Misuse of Drugs Act it was done with no public consultation and very little debate in the house. It’s bit like the TPPA is currently being done… with John Key instead of Nixon at the helm this time acting like a foolish puppy dog for America; The evil man called Nixon at the helms after the assassination of Kennedy.

In a secretly taped recording of Nixon he can be heard saying the following on May 26, 1971 at 10:03am:

Nixon shows he hates jews and pot... and psychiatrists?!

Nixon shows he hates jews and pot… and psychiatrists?!

“Now this is one thing I want. I want a goddam strong statement on marijuana – can I get that out of this sonnofabitching domestic council?

“I mean one on marijuana that just tears the ass out of them. I see another thing in the news about it.

“You know it’s a funny thing, every one of the bastards out there for legalising marjiuana are jewish. what the christ is the matter with the jews bob? what is the matter with them? I spose it’s because most of them are psychiatrists you know there’s so many because all the psychiatrists are jewish . By god we are gonna hit the marijuana thing.  and i want to hit it right square in the puss.  want to hit it [blah blah insane ramblings].”

Our cannabis law is based on hatred for Jews.

By the way I am one quarter Austrian Jew.

And you guys are fairly much directly responsible for that, after our pathetic politicians down in Wellington. I feel John is laughing at punishing us for the poor voter turn out. I voted always by the way.

How come you don’t have a recommendation for the three Cannabis extracts?

I put it to you, that you have failed in your statutory duty and will try to find any way that I can bring a private prosecution against you and your organisation if it’s at all possible, and believe me I’ve been looking pretty hard lately.

Tomachi.

Yours truly, a truly frustrated and tired of waiting person.

PS Also if you see Vicki remind her on this point about the “gateway drug” myth she botched in the interview above. The Prohibition is the gateway, not cannabis. I can somehow tell you know this but you didn’t show this in the interview. If you can’t buy crack cocaine at your local bar or pharmacist, then you certainly won’t be able to buy it at your cannabis dispensary either – it would be stupid of them to stock anything illegal if they had a house full the brim with heavily regulated weed!

PSS Prohibition causes violence and crime. Prohibition is not the ultimate form of regulation, it is actually the abdication of responsibility. Regulation will stop the gangs and prevent people from getting hooked on harder drugs like meth, and YOU should be ashamed of yourselves for not pushing much much harder for a taxed and regulated market for this wonderful herb simply to stop meth and gangs. You have caused un-knowable violence and pain for many people since 2000 AD. Do the right thing. NOW! Hurry! Or else you mite have an accident – karma is a pain.

* the two studies are shown below
** the types of rights I’m referring are shown below
*** NIH Study on cannabis use and bladder cancer 11 years 84,000 men longitudinal study shows 45% reduction with a 95% confidence interval! These results are off the chart obvious that you have missed something crucial in your science. Grab some ganja today because it’s obviously going to save your life, and hurry to quickly and strongly remove it from MODA1975.

  1. A Fair Go For All? Addressing Structural Discrimination in Public Services. July 2012.
    A Fair Go For All? Addressing Structural Discrimination in Public Services. July 2012.

    and also another good excerpt from this report: A Fair Go For All? Addressing Structural Discrimination in Public Services. July 2012.

    CJS 2011 report

    CJS 2011 report

  2. Over-representation of Māori in the criminal justice system: An exploratory report (September 2007) by the Policy, Strategy and Research Group – Department of Corrections.

    Over-representation of Māori in the criminal justice system: An exploratory report (September 2007) by the Policy, Strategy and Research Group - Department of Corrections.

    Over-representation of Māori in the criminal justice system: An exploratory report (September 2007) by the Policy, Strategy and Research Group – Department of Corrections.

Justice is not being served

The Criminal Procedure Act 2011 excludes scientific evidence:

Section 205 (Court may suppress evidence and submissions)

  • The crown is likely to suppress general non-relevant evidence provided during cannabis main defence and appeal on the basis that it’s irrelevant to the case at hand and only supplied to bias the court against the cannabis prohibition law itself or is intended to prejudice a jury to acquit regardless of the facts of the case. A judge is not currently allowed to consider science or question the un-science racist law oddly, unlike most countries. This biasing is known as jury nullification and is sought by the future cannabis accused due to New Zealand’s unique international position of having no constitutionally guaranteed human rights and the resultant inability of district court judges to strike down NZ BORA inconsistent legislation – such as the inclusion of cannabis in the schedules of the Misuse of drugs Act 1975

Section 223 (Right of appeal against determination of first appeal court in regards public interest)

The High Court or the Court of Appeal must not give leave for a second appeal under this subpart unless satisfied that (a) the appeal involves a matter of general or public importance. I believe that there is a great public interest in the reform of our cannabis laws and that only a jury nullification or member of parliament can do it or a member of the EACD can do it.

  • Part of my evidence shows how the MODA conflicts with the BORA regarding Maori and cannabis
  • Evidence to support public support for the taxation and regulation of cannabis
  • Common sense

5 Abuses of the New Zealand Bill of Rights Act 1990

I seek an urgent High Court interim injunction appeal due to the life threatening yet unusual and unintended severe negative effects of the prohibition law on my ability to work, think, live, love and die based on my in-ability to access adequate protections of my human rights:

  • Section 21 My privacy was breached at every stage in this saga, such as the right to an expectation against unreasonable search and seizure while out and about but especially in the privacy in ones own home so long as it does not injure another person
  • Section 27 The right to justice. Irrelevant evidence such as general case law, scientific studies and government reports, legislation and the outcomes of cases in other countries are unlikely to have been deemed admissible to show by defence to a judge alone trial, since he or she would be unable to consider my human rights in any form
  • Section 13 My right to practice my own religion (Cantheism), that considers cannabis sativa a holy sacrament
  • Section 9 and also Section 22 Not to be subjected to cruel treatment and Liberty of the person being the right not to be arbitrarily arrested or detained – I spent 6 nights in Mount Eden Prison over new years eve, finally getting my house keys back on January 6th! The substance police alleged was meth for supply was thought to me to be MDMA but which turned out to be PCP according to the ESR test results.
  • Section 9 and also Section 22 This occurred again on 18 June with NZ’s smallest amount of meth ever found in my locked bedroom when I was not even home during a warrantless search: 0.017 grams again this resulted in 2 nights in Mt Eden remand on meth supply charges that got dropped
  • My right to a trial by a jury of my peers – cannabis possession does not qualify for jury trial, yet this is the only way I can move to have my human rights considered

Near the end of the US Liquor Prohibition juries ceased convicting based on law and decided instead to deliver justice. It is the juries responsibility to deliver justice not uphold the law, established in 1670 Tower of London case of William Penn who was charged with speaking in the street but was not permitted to show evidence in trial (to bias the jury against the bad anti-quaker law) and when the jury found him not guilty the entire jury were sent to prison and fined a years wages.

After 1670 juries would be unable to be punished for their thoughts – this has not happened in New Zealand yet, except perhaps with the Waihopai Three Nullification.

Evidence Supporting a Jury Nullification for any Cannabis Related Offence

Proceeds of Crime Data – Past 10 years – Shows prohibition to produce inconsistent rates of return

Based on the data from my official information act request of 15 June 2013

(45693_Atkinson official information proceeds crime.pdf)

When plotted by city and against time one can see that the proceeds of crime act is not a very consistent method of extracting tax revenue from the illegal drugs market in NZ.

Time corelation shows that this is not a very effective tax collection method

Time correlation shows that this is not a very effective tax collection method

The following table suggests that Forfeiture order amounts could potentially be unfairly implemented across the country, with no proceeds whatsoever over a 10 year period from Napier, New Plymouth, Hamilton, Invercargill; but with extremely high amounts from Whangarei equivalent to $67 per person!

Forfeiture order amounts by city shows nothing for four cities and heaps for Whangarei

Forfeiture order amounts by city shows nothing for four cities and heaps for Whangarei

Source: 45693_Atkinson official information proceeds crime.pdf

Proceeds of crime spreadsheet prepared for one of my many official information act requests. What a waste of my time and tax payers money yeah?

Proceeds of crime spreadsheet prepared for one of my many official information act requests. What a waste of my time and tax payers money yeah?

as signed off by Graeme Astle – bless him and give thanks and praise for Jahs work!

Graeme Astle Signature

Graeme Astle Signature ref 45693


A jury would have been asked to consider the benefits of tax revenue to our economy

Colorado Tax Revenue Chart

Colorado Tax Revenue Chart

Colorado Tax Allocation

Colorado Tax Allocation

A jury would be asked to consider our high rates of incarceration and the downsides of this

The chart below is sourced from corrections own data and shows a ballooning Community Detention block, for XLS data see: http://www.legalise.org.nz/home-detention/

Use of Home Detentions is masking NZ's Drug Problem

Use of Home Detentions is masking NZ’s Drug Problem

NZ prison population is some of the highest in the world NOT INCLUDING home detention, community detention

NZ prison population is some of the highest in the world NOT INCLUDING home detention, community detention

Illustration shows that Marijuana is associated with creativity

Cannabis Promotes Creativity

Cannabis Promotes Creativity

Thanks to this man, the police have actually been quietly decriminalising cannabis for the past 20 years

Greg O'Connor Sept 08 300dpi_0

Greg O’Connor Sept 08

NZPA President Greg O'connor Visits Legal Cannabis Store in Colorado

NZPA President Greg O’connor Visits Legal Cannabis Store in Colorado

Trending down in drug apprehensions

Trending down in drug apprehensions

In 2012 only 8 people were convicted of consuming cannabis according to

Official-Information-Act-Request-201307081002.pdf

Only 8 people were convicted of consuming cannabis in 2012

Only 8 people were convicted of consuming cannabis in 2012

Portugal has managed to cut it’s drug addiction rates in half through public health policies

Portugals president explains what he did to cut drug addiction in half

Portugals president explains what he did to cut drug addiction in half

Pot Friendly Countries

NZ Has a poor attitude compared to nearly every other developed country

NZ Has a poor attitude compared to nearly every other developed country

Cost of administering sentences by sentence type

The cost of administering home detention and prison

The cost of administering home detention and prison

No prosecution for cannabis should proceed because it is no longer in the public interest

58 Entirely Unique Website Domains Carried Stories About Kelly van Gaalen

58 Entirely Unique Website Domains Carried Stories About Kelly van Gaalen

The United Nations said this stuff about our poor human rights: (!)

The UN comments on NZ lack of rights in the Fourth Periodic Report under the convenant on civil and political rights.

The United Nations tells NZ to rationalise cannabis laws

The United Nations tells NZ to rationalise cannabis laws

and again to remind New Zealand again during the fifth periodic report:

UN comments on NZ's poor human rights stance

UN comments on NZ’s poor human rights stance

This is fucked to put it bluntly I’m sorry.

An excerpt from 15 YEARS OF THE NZ BILL OF RIGHTS: TIME TO CELEBRATE, TIME TO REFLECT, TIME TO WORK HARDER? By Petra Butler:

Petra Butler comments about the history of our crippled human rights laws

Petra Butler comments about the history of our crippled human rights laws

Thomas Jefferson said “If a law is unjust, a man is not only right to disobey it, he is obligated to do so.”

thomas-jefferson

The results of a very long running US GALLUP poll on whether the use of marijuana should be made legal or not shows a steady increase from 12% right up to 58%

US_gallop-cannabis-legalization-poll

The world’s first ever marijuana conviction shown. 4 years prison for 2 joints. Prisoner number 18,699. Numbers would get to the point where America has more people in prison than Chinese prisons!

Worlds First Cannabis Convict

Worlds First Cannabis Convict

We can thank Nixon for this terribly brutal regime we are still subjected to.

 



350million drug-harm

Sue Grey PDF



Maybe I was stoned and missed it, but a momentus event occurred in April!

You are receiving this newsletter because Re-Legalise NZ decided to “carry” a transmission from Damien O’Connor. This was a decision SecretStoner made and is a one off – for more you would need to subscribe to Damien O’Connor’s news list personally on his website. We respect your privacy and will not share your details with any 3rd party.

Copyright © 2016 Re-Legalise NZ 

 

 

April 2016 newsletter from Damien O’Connor
MP West Coast/Tasman

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Bennett Morgan (left) presents the petition with over 4000 signatures in support of Helen Kelly’s access to medical cannabis. Damien’s Members Bill was placed in the Ballot the day before.

Damien lodges medicinal cannabis approval bill

Damien O’Connor has lodged a Member’s Bill to make it easier for patients like the late Alex Renton to access medicinal cannabis products.

“I supported Alex Renton’s family in their quest to get approval for medicinal cannabis in a hope it could improve his desperate situation.

“The current system is too bureaucratic and it is unclear where the final approval lies.

“My Bill makes the approval process simpler but has appropriate safeguards.

“The key change is the Minister must not prevent the supply and administration of processed cannabis products to a person considered by a registered medical practitioner to be either in the final stages of a terminal illness, or have a permanent condition that causes significant pain or impairment.

“This is a Member’s Bill I hope will progress the issue and, if drawn, will enable Parliament to properly consider the value of access to medicinal cannabis. Change is supported by the majority of New Zealanders,” says Damien O’Connor.

The future of work on the West Coast

Small business and technology

Labour’s Future of Work Commission, chaired by Grant Robertson is looking at a comprehensive plan for ensuring decent work opportunities and secure incomes for New Zealanders in a world that is changing faster than we have ever seen before.

Buller locals know all about rapid change as the region comes to terms with the loss of Solid Energy, Oceana, Bathurst and Holcim, among global changes in industry and the boom and bust cycles of coal and diary.

There has been much talk about diversification and how to revive the economy. The brightest prospects on the horizon are focused on tourism and technology, driven by a variety of smaller ventures, rather than one big industry, such as coal or cement.

A partnership between several Westport organisations such as Buller Reap and the Buller District Council has launched the Epic project, which focuses on technology to stimulate small business. They are hosting a business networking event with Ben Dellaca on 15 April.  Ben grew up in Westport and is now on a mission to bring digital innovation to Buller. The first Epic breakfast with Guy Ryan was very successful and has inspired a number of new initiatives. The Epic hub will also provide other key start-up services such as fibre optic internet and open plan office facilities to encourage and support entrepreneurs.

Co-Starters is a comprehensive learning and support programme that will also soon get underway in Westport. It aims to help people get their business ideas going. It is a 9 week course utilising guest speakers and peer support to develop ventures. Tai Poutini Polytech is also running a small business management course to provide the nuts and bolts skills for small business entrepreneurs.

Automation is predicted to wipe out nearly half the jobs that exist right now within a decade and a half, so Labour’s Future of Work starts with technology because it is driving much of the change.

“We are calling this digital equality”, Grant Robertson said, “It is the modern version of saying that everyone deserves a fair go, except this time it is about getting us all connected and knowing how to make the most of technology”.

This means encouraging small businesses and social entrepreneurs. Not just in our cities but also by supporting development in our regions that is sustainable and high value.

About Labour’s Future of Work Commission 

Labour backs young entrepreneurs

The next Labour Government will encourage innovative and driven young entrepreneurs to create a viable business by providing training, a business mentor and up to $20,000 capital for successful applicants in its Young Entrepreneurs Plan, Leader of the Opposition Andrew Little says.

“The changing nature of work is creating a new generation of smart, innovative young Kiwis who need nurturing and capital to get successful ideas off the ground.

“We know that not everyone thrives in formal education or training and some of our best-known entrepreneurs learnt everything they know on the job.

“In January we announced our first major Future of Work policy – three years free training and education across a person’s lifetime. Today’s announcement is an extension of that, allowing smart, young entrepreneurs aged 18-23 to cash that in and capitalise on a great business idea.

This would be in the form of a one-off start-up grant with the safety net of funded business training, an ongoing business mentor and a business plan approved by an independent panel of experts.

“The grants will be capped at 100 per year for the first three years.

“Today’s young people are growing up in an environment that promotes entrepreneurial thinking in ways older generations did not. Their working careers are more likely to involve generating more of their own income and less stable work. Encouraging their business skills will be crucial.

“There are many barriers to young people accessing finance to back good business ideas. But this plan is about much more than just capital. Putting young Kiwis through business training, providing them with an experienced business mentor and requiring a thorough business plan to be successful for the grant provides a real safety net for their idea.

“This will offer real opportunities to young people who have a good business brain and the drive to make their ideas work so they can not only be a part of the Future of Work, but help determine the future of work.

“New Zealand needs more successful entrepreneurs and this small investment will help create the next generation of them,” says Andrew Little.

Time for a tourism levy

by Damien O’Connor

The West Coast has experienced a strong tourist season and people continue to visit our amazing region. That’s great news for anyone with a business connected in any way to travelers.

But what is concerning is the increasing amount of unwanted, misplaced and sickening human effluent from the top of our region to the bottom.  Almost every roadside stopping point is strewn with obvious signs of people who needed a toilet.

While everyone understands urgent needs, the absence of toilets and clear directions for visitors means our reputation for spectacular, pristine scenery is at risk. We can’t continue to ignore the problem.

The expectation that local councils and ratepayers should stump up with the bylaws, the facilities and the maintenance costs are completely unrealistic, especially on the Coast where we have a small population in a large geographical area in which rates are already proportionately among the highest in the country.

I promoted a conservation levy of $25 paid by every visitor to NZ. It could be included in their airline ticket and the money administered by a fund available to councils and DoC to pay for toilets, signage and infrastructure to protect our environment from degradation. Visitors could be rewarded with a National Park pass book, which would be stamped as a memento of their journey.

A campaign run by a sector in the tourism industry that claimed the costs would discourage tourism, was both stupid and self serving. It’s time for the tourism industry to push for the conservation levy. At the moment visitors pay nothing and many have no idea of the value of their experience. The status quo is not sustainable and tourism should jump on board to change it.

Around the electorate

From Wellington

Latest press releases from Labour HQ

Documents prove Crown land sell-off a fiasco

Posted by Phil Twyford on April 12, 2016
New documents obtained by Labour prove Nick Smith lied when he denied the Government had identified land occupied by substations and cemeteries as Crown land to be sold off for housing, Labour’s Housing spokesperson Phil Twyford says. More

Tax history should be an open book for leaders

Posted by Andrew Little on April 12, 2016
In revealing his tax history for the past six years today, Leader of the Opposition Andrew Little says transparency is crucial for public confidence in political leaders. More

Full transparency needed from PM and Government

Posted by Andrew Little on April 11, 2016
John Key’s proposal to appoint a ‘tax expert’ to review our foreign trusts doesn’t go far enough and he must instead launch a full independent inquiry into the details coming out of the Panama Papers, says Opposition Leader Andrew Little. More

Govt worried about public scrutiny – cuts down TPP process

Posted by David Clark on April 08, 2016
The Government wants to trim the process for hearing TPP submissions to get the controversial legislation off the agenda for election year in a shocking case of political expediency, Labour’s Trade and Export Growth spokesperson David Clark says. More

O’Connor lodges medicinal cannabis approval bill

Posted by Damien O’Connor on April 07, 2016
Damien O’Connor has lodged a Member’s Bill to make it easier for patients like the late Alex Renton to access medicinal cannabis products. “I supported Alex Renton’s family in their quest to get approval for medicinal cannabis in a hope it could improve his desperate situation” Damien O’Connor said. More

To read more press releases, news and information about the Labour Party, visit www.labour.org.nz

Thanks to everyone who responded to last month’s survey. Here are the results:

Should our police services be centralised?

  • Yes 18.2%
  • Dont know 9.1%
  • No 72.7%

Blackball Mayday Events

FRIDAY night debate at the Blackball Workingmen’s Club – Runanga vs Blackball: That West Coast leadership remains hopeless.

SATURDAY Forum at the Mines Rescue Centre, Runanga.  Last year’s day was robust and thought-provoking, with the various speakers articulating a way forward for the region.  What have they got to say a year later?

SUNDAY Community Day outside the Runanga Miners’ Hall, McGowan St, Runanga.  There will be baking, biking, poetry and solidarity. Come and join us!


Facebook page

 Friday April 29 to Sunday May 1

A weekend of conservation and entertainment at Punakaiki.

Diary & Events

APRIL 19
Wills and Trusts Seminar
12.15 pm The Auditorium, St Thomas’ Anglican Church, 101 High Street Motueka

APRIL 15 to 16
West Coast Ag Fest Cass Square Hokitika.

APRIL 17 to 22
National Farm Forestry Assoc. Conference, Hokitika

APRIL 20
Trio Éclat concert
7.30pm, Chanel Arts Centre, Motueka

APRIL 29
Mayday Blackball-Rununga Debate at the Blackball Working Mens Club.

APRIL 30
Mayday forum at Mines Rescue, Rununga

APRIL 30
Westport Warrior endurance race
North Beach Westport

MAY 1
Rununga May Day fun day, Rununga Miners Hall

APRIL 30 / MAY 1
Return of the Petrel Festival, Punakaiki

MAY 4
Community & Whanau meeting
12 noon, Community House, Motueka

MAY 5
“Mothers & Fathers”: A play by Joe Musaphia
Thursday to Saturday, May 5th and 7th, 7.30pm
Imagine Theatre, Woodlands Ave, Motueka.

MAY 5
Hokitika Mid-Winter Festival

MAY 8
Jennian Homes Mothers Day Fun Run / Walk
9 am at the Solid Energy Centre Westport

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The Argus Tradition

The Grey River Argus was the first newspaper published in Greymouth, appearing in November 1865. The Grey River Argus supported the Labour Movement. For many years the legend New Zealand’s pioneer Labour daily appeared on the masthead. I am carrying on this proud tradition and the West Coast-Tasman Argus will be my way of keeping the electorate up to date. Damien O’Connor
You are receiving this newsletter because Re-Legalise NZ decided to “carry” a transmission from Damien O’Connor. This was a decision SecretStoner made and is a one off – for more you would need to subscribe to Damien O’Connor’s news list personally on his website. We respect your privacy and will not share your details with any 3rd party.

Copyright © 2016 Re-Legalise NZ

 



henry-viiiIn 1533, King Henry VIII decreed that all landholders set aside one-quarter acre for the cultivation of hemp for every sixty acres of land that they tilled, in order to provide the necessary fibre required by the nation. This was to satisfy the increased demand for rope and sailcloth for King Henry’s VIII new navy.

Queen-Elizabeth-I_Darnley-Portrait_860x440In 1563 Queen Elizabeth I reintroduced the law to expand her navy and she added a £5 fine for any eligible landlord who failed to comply. From then on the demand increased and the hemp industry became a very important industry to the British economy. They had to improve the supply of this strategic raw material when in the 1630s the British sped up their colonisation of the new world.Elizabeth_I_of_England_Hardwick_1592

1. Deitch, Robert (2003) Hemp: American history revisited: the plant with a divided history. page 12. Algora Publishing. Accessed 2010-01-16.
Research and text © Hempshopper Amsterdam.



 

http://www.parliament.nz/en-nz/pb/legislation/bills/00DBHOH_BILL56948_1/drug-and-alcohol-testing-of-community-based-offenders

Drug and Alcohol Testing of Community-based Offenders, Bailees, and Other Persons Legislation Bill

This Bill enables the Department of Corrections and the New Zealand Police to require community-based offenders and bailees, if they are subject to conditions prohibiting the use of drugs and alcohol, to undergo drug and alcohol testing to ensure compliance with these conditions.

(Formerly Drug and Alcohol Testing of Community-based Offenders and Bailees Legislation Bill)

http://www.parliament.nz/en-nz/pb/legislation/bills/00DBHOH_BILL66352_1/misuse-of-drugs-amendment-bill

Misuse of Drugs Amendment Bill

(Formerly part of Organised Crime and Anti-corruption Legislation Bill)

Member in charge: Hon Amy Adams
Type of bill: Government
Parliament: 51
Bill no: 219-3L
Third reading: 4/11/15
Royal assent: 6/11/15
Act: Misuse of Drugs Amendment Act 2015 (15/106)

 



It’s a nice idea but has some issues, mostly the maximum (or is it minimum? That I could understand!) THC content limit which is shocking and arbitrary and non-scientific, and the fact we’d still have a black market for un-licensed bud, and no way to purchase whole-product medical buds (except pre-ground and pre-rolled or by growing it yourself). On the positive side it would be fantastic to have absolutely any movement at all on the subject, and by the sounds of it would create a centralised place to buy and sell government approved cannabis products. In effect, a government registry would be fantastic since you would have literally thousands of products to choose from eventually – if I understand it properly.

This from Chris Fowlie at hempstore:

Under Wilkin’s proposed model the government does not grow the cannabis, it licenses production just like with hemp to a variety of producers – some may be indoor, some may be outdoor, or organic, the idea is there would be a variety of cannabis producers making a variety of products. And by “cannabis products” he means cannabis with some form of processing – so it can be distinguished from black market cannabis – e.g. ready rolled joints with logos, balms, tinctures, pre-ground buds for vaping, basically anything except unprocessed bud. Most tobacco smokers do not insist on unprocessed tobacco leaves, they are happy to purchase “tobacco products”, so other than “fuck the government” purists who think anything except “no rules” will be a disaster, I think most cannabis users would be very well served by this model – and if they want more, or insist on smoking bud, they can grow their own, or register as medical users. There is no model that will make 100% of the people 100% happy, but this goes a long way to keeping most people mostly happy (including traditional opponents like police, etc), which is what we will need to bring about law reform.

This from Wilkins’ page at Massey

Approved cannabis products would have a limit to the amount of THC (tetrahydrocannabinol – the principal psychoactive ingredient in cannabis) allowed, and a required minimum level of CBD (cannabidiol – the non-psychoactive ingredient, known for its medicinal benefits).

They would only be produced and sold by the government, ensuring a high price to restrict demand and generating tax revenue to support treatment counselling, health services and enforcement. “The Government will be the only producer and the only seller, and that’s a means to keep the price high and also collect tax.”



Excerpts from a fantastic thesis by Randy E. Barnett that shares the same title as this post.

Some drugs make people feel good. That is why some people use them. Some of these drugs are alleged to have side effects so destructive that many advise against their use. The same may be said about statutes that attempt to prohibit the manufacture, sale, and use of drugs. Advocating drug prohibition makes some people feel good because they think they are “doing something” about what they believe to be a serious social problem. Others who support these laws are not so altruistically motivated. Employees of law enforcement bureaus and academics who receive government grants to study drug use, for example, may gain financially from drug prohibition. But as with using drugs, using drug laws can have moral and practical side effects so destructive that they argue against ever using legal institutions in this manner.

One might even say—and not altogether metaphorically—that some people become psychologically or economically addicted to drug laws.1 That is, some people continue to support these statutes despite the massive and unavoidable ill effects that result. The psychologically addicted ignore these harms so that they can attain the “good”—their “high”—they perceive that drug laws produce. Other drug-law users ignore the costs of prohibition because of their “economic” dependence on drug laws; these people profit financially from drug laws and are unwilling to undergo the economic “withdrawal” that would be caused by their repeal.

Both kinds of drug-law addicts may deny their addiction by asserting that the side effects are not really so terrible or that they can be kept “under control.” The economically dependent drug-law users may also deny their addiction by asserting that (1) noble motivations, rather than economic gain, lead them to support these statutes; (2) they are not unwilling to withstand the painful financial readjustment that ending prohibition would force them to undergo; and (3) they can “quit” their support any time they want to—provided, of course, that they are rationally convinced of its wrongness.

Their denials notwithstanding, both kinds of addicts are detectable by their adamant resistance to rational persuasion. While they eagerly await and devour any new evidence of the destructiveness of drug use, they are almost completely uninterested in any practical or theoretical knowledge of the ill effects of criminalising such conduct.4 Yet in a free society governed by democratic principles, these addicts cannot be compelled to give up their desire to control the consumption patterns of others. Nor can they be forced to support legalisation in spite of their desires. In a democratic system, they may voice and vote their opinions about such matters no matter how destructive the consequences of their desires are to themselves or, more importantly, to others. Only rational persuasion may be employed to wean them from this habit. As part of this process of persuasion, drug-law addicts must be exposed to the destruction their addiction wreaks on drug users, law enforcement, and on the general public. They must be made to understand the inherent limits of using law to accomplish social objectives.

Later we get this nice summary:

We can conclude then that the end or purpose of drug laws is to discourage people from engaging in risky activity in which they wish to engage either because they desire the intoxicating effects they associate with the consumption of a drug or because they desire the profit that can be realised by supplying intoxicating drugs to others.15 The means that drug laws employ to accomplish this end is using force against those who would engage in such activities, either to prevent them from doing so or to punish those who nonetheless succeed in doing so.

But what about those who are not discouraged and who engage in such conduct anyway? Does the practice of punishing these persons make life better or worse for them? The answer is clear. As harmful as using drugs may be to someone, being imprisoned often makes matters much worse.

Normally when considering matters of legality, we are not concerned about whether a law punishes a lawbreaker and makes him worse off. Indeed, normally such punishment is deliberately imposed on the lawbreaker to protect someone else who we consider to be completely innocent—like the victim, or potential victim, of a rape, robbery, or murder.21 We are therefore quite willing to harm the lawbreaker to protect the innocent. In other words, the objects of these laws are the victims; the subjects of these laws are the criminal.

Drug laws are different in this respect from many other criminal laws. With drug prohibition we are supposed to be concerned with the well-being of prospective drug users. So the object of drug laws—the persons whom drug laws are supposed to “protect”—are often the same persons who are the subject of drug laws. Whenever the object of a law is also its subject, however, a problem arises. The means chosen for benefiting prospective drug users seriously harms those who still use drugs and does so in ways that drugs alone cannot: by punishing drug users over and above the harmful effects of drug use. But the harm done by drug prohibition to drug users goes beyond the direct effects of punishment.

 Higher prices lead to more infection

Higher prices can also make drug use more hazardous for users. Intravenous injection, for example, is more popular in countries where high drug prices caused by prohibition drive users to the most “efficient” means of ingesting the drug. In countries where opiates are legal, the principal methods of consumption are inhaling the fumes of heated drugs or snorting. Before the Harrison Act of 1914, “when opiates were cheap and plentiful, they were very rarely injected. Moreover, injection is rare in those Asian countries where opiates are inexpensive and easily available.” While physical dependence may result from either inhalation or snorting, neither is as likely as intravenous injections to result in an overdose. And consumption by injection can cause other health problems as well. For example: “Heroin use causes hepatitis only if injected, and causes collapsed veins and embolisms only if injected intravenously.” Finally, the scourge of HIV-AIDS has been caused, in part, by the sharing of unsterilised needles by drug users.

Drug Laws Make Drug Users Buy from Criminals

The following basically embodies the concept of “The prohibition is the gateway not cannabis”.

People who still wish to use drugs are forced to do business with the kind of people who are willing to make and sell drugs in spite of the risk of punishment. Such transactions must deliberately be conducted away from the police. This puts drug users in great danger of physical harm in two ways.

Most violent crime stems from prohibition not the drug

Second, users are likely to be the victims of crime. I would estimate that approximately half the murder cases I prosecuted as an Assistant States Attorney in Cook County, Illinois were “drug related” in the sense that the victim was killed because it was thought he had either drugs or money from the sale of drugs. Crimes are also committed against persons who seek out criminals from whom to purchase prohibited drugs. Because drug users and dealers want to avoid the police, crimes against these groups are unlikely to be reported. As a result, these crimes are likely brought to the attention of the authorities only when a victim’s body is found.

In 1979, I obtained the confessions that were ultimately used in a prosecution involving the savage murder of three young men. 34 One of the three had approached four members of the Latin Kings to purchase marijuana. When his initial attempt to do business with the gang members was rebuffed, he mistakenly believed that this was due to a lack of trust—rather than a lack of marijuana, which was the case. To ingratiate himself with the gang members, he boasted (falsely) about his gang-affiliated friends and his gang membership. Unfortunately the persons he named were members of a rival street gang, the Latin Eagles. The gang members then told him that they could supply marijuana after all and asked the three to accompany them to an alley. There they were held at gun point and eventually stabbed to death. These young men were not members of any street gang. These are drug-law-related deaths. Three young men are dead because drug laws prevented them from buying marijuana cigarettes as safely as they could buy tobacco cigarettes. While smoking either kind of cigarette may have been hazardous to their health, that issue is now moot. Where and how are their deaths registered in the cost-benefit calculation of drug-law advocates?



Using data mining techniques, I’ve produced this handy guide to medical cannabis for professionals curious about it’s application. 419 studies were, 199 of which were fully controlled studies.

Medical Cannabis Cheat Sheet

Medical Cannabis Cheat Sheet

PDF:  1 page guide  Medical Cannabis Cheat Sheet also I prefer this  version with artistic edge made from the studies text.

XLSX: source data for cheat sheet 419 studies data mining pivot table.xlsx

419 clinical studies of cannabis have taken place. Burn in hell Peter Dunne you are scum of the earth.

Clinical Studies and Case Reports

On this site you will find clinical studies with cannabis or single cannabinoids in different diseases and case reports on the use of cannabis by patients.

 


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Diagnosis Title Author(s) Year Medication(s) Design Major outcome(s)
Show Dependency/withdrawal Safety of oral dronabinol during opioid withdrawal in humans Jicha CJ, Lofwall MR, Nuzzo PA, Babalonis S, Elayi SC, Walsh SL. 2015 Delta-9-THC Controlled study 40 mg of THC caused increased heart rate and anxiety, which made dose-reduction necessary
Show Epilepsy Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy Press CA, Knupp KG, Chapman KE 2015 Cannabis Open study About one third of children suffering from different forms of epilepsy experienced a more than 50 % reduction in seizures by the use of oral cannabis extracts.
Show Pain Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy Wallace MS, Marcotte TD, Umlauf A, Gouaux B, Atkinson JH 2015 Cannabis Controlled study Inhaled cannabis demonstrated a dose dependent reduction in peripheral treatment-refractory neuropathic pain.
Show Profiles of medicinal cannabis patients attending compassion centers in rhode island. Zaller N, Topletz A, Frater S, Yates G, Lally M. 2015 Cannabis Survey Most participants report that medicinal cannabis improves their pain symptomology.
Show Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin on Food Reward and Aversion in Healthy Volunteers. Tudge L, Williams C, Cowen PJ, McCabe C 2015 Other cannabinoids Controlled study The natural cannabinoid tetrahydrocannabivarin (THCV) altered the nerve response to pleasant and unpleasant stimuli in a way that it “suggests therapeutic activity in obesity.
Show Posttraumatic stress disorder The efficacy of nabilone, a synthetic cannabinoid, in the treatment of PTSD-associated nightmares: A preliminary randomized, double-blind, placebo-controlled cross-over design study. Jetly R, Heber A, Fraser G, Boisvert D. 2015 Nabilone Controlled study Nabilone reduced nightmares.
Show Smoking and Diabetes Mellitus: Results from Meta-analysis with Eight Independent Replication Samples Alshaarawy O, Anthony JC. 2015 Cannabis Survey Cannabis use was associated with a 30% reduction of diabetes risk
Show Pain Experience of adjunctive cannabis use for chronic non-cancer pain: Findings from the Pain and Opioids IN Treatment (POINT) study. Degenhardt L, Lintzeris N, Campbell G, Bruno R, Cohen M, Farrell M, Hall WD. 2015 Cannabis Survey Pain patients, who receive opioids, experience better pain relief if they also take cannabis.
Show HIV/AIDS High-intensity cannabis use associated with lower plasma human immunodeficiency virus-1 RNA viral load among recently infected people who use injection drugs. Milloy MJ, Marshall B, Kerr T, Richardson L, Hogg R, Guillemi S, Montaner JS, Wood E. 2015 Cannabis Open study At least daily cannabis use was associated with significant lower plasma HIV viral loads.
Show Cancer Patterns of Use of Medical Cannabis Among Israeli Cancer Patients: A Single Institution Experience. Waissengrin B, Urban D, Leshem Y, Garty M, Wolf I. 2015 Cannabis Open study Cannabis use “is perceived as highly effective” by some patients with advanced cancer.
Show Cancer;Nausea/vomiting Dronabinol Treatment of Refractory Nausea and Vomiting Related to Peritoneal Carcinomatosis. Hernandez SL, Sheyner I, Stover KT, Stewart JT. 2015 Delta-9-THC Open study THC may be very effective in the treatment of nausea and vomiting in end-stage cancer.
Show Appetite loss/weight loss;Cancer;Nausea/vomiting;Pain Improving Quality of Life With Nabilone During Radiotherapy Treatments for Head and Neck Cancers: A Randomized Double-Blind Placebo-Controlled Trial Côté M, Trudel M, Wang C, Fortin A. 2015 Nabilone Controlled study Nabilone did not reduce pain and nausea in patients treated for head and neck cancer.
Show Pain Single dose delta-9-tetrahydrocannabinol in chronic pancreatitis patients: analgesic efficacy, pharmacokinetics and tolerability de Vries M, van Rijckevorsel DC, Vissers KC, Wilder-Smith OH, van Goor H(; Pain and Nociception Neuroscience Research Group 2015 Delta-9-THC Controlled study No effect of a single low dose of THC on abdominal pain resulting from chronic pancreatitis in clinical study.
Show Dependency/withdrawal;Pain The prescription of medical cannabis by a transitional pain service to wean a patient with complex pain from opioid use following liver transplantation: a case report. Meng H, Hanlon JG, Katznelson R, Ghanekar A, McGilvray I, Clarke H. 2015 Cannabis Uncontrolled case report The use of cannabis reduced opioid consumption
Show Alzheimer’s disease Tetrahydrocannabinol for neuropsychiatric symptoms in dementia: A randomized controlled trial. van den Elsen GA, Ahmed AI, Verkes RJ, Kramers C, Feuth T, Rosenberg PB, van der Marck MA, Olde Rikkert MG. 2015 Delta-9-THC Controlled study No reduction in NPS by low-dose THC (3×1.5mg), though it is well-tolerated
Show Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users. Hindocha C, Freeman TP, Schafer G, Gardener C, Das RK, Morgan CJ, Curran HV. 2015 Cannabis;Delta-9-THC;Cannabidiol Controlled study Improvement of recognition of emotional facial affect by CBD and attenuation of the impairment induced by THC
Show The effect of five day dosing with THCV on THC-induced cognitive, psychological and physiological effects in healthy male human volunteers: A placebo-controlled, double-blind, crossover pilot trial. Englund A, Atakan Z, Kralj A, Tunstall N, Murray R, Morrison P. 2015 Delta-9-THC Controlled study Inhibition of some of the well-known effects of THC by THCV and potentiation of other effects
Show Pain The Pharmacokinetics, Efficacy, Safety, and Ease of Use of a Novel Portable Metered-Dose Cannabis Inhaler in Patients With Chronic Neuropathic Pain: A Phase 1a Study Eisenberg E, Ogintz M, Almog S 2014 Cannabis Open study A significant reduction in pain intensity was achieved after cannabis inhalation with a vaporizer.
Show Dependency/withdrawal Nabiximols as an agonist replacement therapy during cannabis withdrawal: a randomized clinical trial Allsop DJ, Copeland J, Lintzeris N, Dunlop AJ, Montebello M, Sadler C, Rivas GR, Holland RM, Muhleisen P, Norberg MM, Booth J, McGregor IS 2014 Cannabis Controlled study Sativex had no relevant long-term effect on cannabis dependence
Show Pain A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment Serpell M, Ratcliffe S, Hovorka J, Schofield M, Taylor L, Lauder H, Ehler E 2014 Cannabis Controlled study Significant improvements in pain, sleep quality and subjective evaluations of patients.
Show Parkinson’s disease Effects of cannabidiol in the treatment of patients with Parkinson’s disease: an exploratory double-blind trial Chagas MH, Zuardi AW, Tumas V, Pena-Pereira MA, Sobreira ET, Bergamaschi MM, dos Santos AC, Teixeira AL, Hallak JE, Crippa JA 2014 Cannabidiol Controlled study Significant improvement in well-being. No effects on motor functioning or neuroprotection.
Show Endocannabinoids control platelet activation and limit aggregate formation under flow. De Angelis V, Koekman AC, Weeterings C, Roest M, de Groot PG, Herczenik E, Maas C. 2014 Other cannabinoids Open study Activation of cannabinoid receptors by cannabis use reduces platelet activation and blood clotting.
Show Traumatic brain injury Effect of marijuana use on outcomes in traumatic brain injury. Nguyen BM, Kim D, Bricker S, Bongard F, Neville A, Putnam B, Smith J, Plurad D. 2014 Cannabis Open study A positive THC screen is associated with decreased mortality in adult patients sustaining TBI [traumatic brain injury].
Show Safety and pharmacokinetics of oral delta-9-tetrahydrocannabinol in healthy older subjects: A randomized controlled trial. Ahmed AI, van den Elsen GA, Colbers A, van der Marck MA, Burger DM, Feuth TB, Rikkert MG, Kramers C. 2014 Delta-9-THC Controlled study THC appeared to be safe and well tolerated by healthy older individuals.
Show Nausea/vomiting Cannabis for intractable nausea after bilateral cerebellar stroke. Adhiyaman V, Arshad S. 2014 Cannabis Uncontrolled case report A woman with intractable nausea after cerebellar stroke responded well to a treatment with THC.
Show Pain;Posttraumatic stress disorder;Sleep disorder Use of a Synthetic Cannabinoid in a Correctional Population for Posttraumatic Stress Disorder-Related Insomnia and Nightmares, Chronic Pain, Harm Reduction, and Other Indications: A Retrospective Evaluation. Cameron C, Watson D, Robinson J. 2014 Nabilone Open study Nabilone caused significant improvements in insomnia, nightmares, chronic pain and other symptoms in patients suffering from posttraumatic stress disorder (PTSD).
Show Multiple sclerosis Long-term effectiveness and safety of nabiximols (tetrahydrocannabinol/cannabidiol oromucosal spray) in clinical practice. Flachenecker P, Henze T, Zettl UK. 2014 Cannabis Open study Researchers found that “real-life data confirm the long-term effectiveness and tolerability of nabiximols [Sativex] for the treatment of resistant MSS [multiple sclerosis spasticity].
Show Posttraumatic stress disorder Preliminary, open-label, pilot study of add-on oral Δ9-tetrahydrocannabinol in chronic post-traumatic stress disorder. Roitman P, Mechoulam R, Cooper-Kazaz R, Shalev A. 2014 Delta-9-THC Open study THC caused significant improvements in post-traumatic stress disorder (PTSD).
Show Parkinson’s disease Cannabis (medical marijuana) treatment for motor and non-motor symptoms of Parkinson disease: an open-label observational study. Lotan I, Treves TA, Roditi Y, Djaldetti R. 2014 Cannabis Open study Analysis of specific motor symptoms revealed significant, also sleep and pain improvement after treatment with cannabis.
Show Multiple sclerosis Nabiximols (THC/CBD oromucosal spray, Sativex®) in clinical practice–results of a multicenter, non-interventional study (MOVE 2) in patients with multiple sclerosis spasticity. Flachenecker P, Henze T, Zettl UK. 2014 Cannabis Open study The cannabis extract Sativex provided relief in 74.6% of participants.
Show Posttraumatic stress disorder Using cannabis to help you sleep: heightened frequency of medical cannabis use among those with PTSD. Bonn-Miller MO, Babson KA, Vandrey R. 2014 Cannabis Survey Patients with high PTSD scores were more likely to use cannabis to improve sleep, and for coping reasons more generally.
Show Sleep disorder Impact of Dronabinol on Quantitative Electroencephalogram (qEEG) Measures of Sleep in Obstructive Sleep Apnea Syndrome. Farabi SS, Prasad B, Quinn L, Carley DW. 2014 Delta-9-THC Open study THC treatment yielded a shift in EEG (electroencephalogram) power toward delta and theta frequencies and a strengthening of normal rhythms in the sleep.
Show Multiple sclerosis;Spasticity Clinical experience with THC:CBD oromucosal spray in patients with multiple sclerosis-related spasticity. Koehler J, Feneberg W, Meier M, Pöllmann W. 2014 Cannabis Open study The mean spasticity decreased by 57%.
Show Multiple sclerosis;Spasticity Clinical experiences with cannabinoids in spasticity management in multiple sclerosis. Lorente Fernández L, Monte Boquet E, Pérez-Miralles F, Gil Gómez I, Escutia Roig M, Boscá Blasco I, Poveda Andrés JL, Casanova-Estruch B. 2014 Cannabis Open study The cannabis extract was effective in 80% of patients.
Show Alzheimer’s disease Dronabinol for the treatment of agitation and aggressive behavior in acutely hospitalized severely demented patients with noncognitive behavioral symptoms. Woodward MR, Harper DG, Stolyar A, Forester BP, Ellison JM. 2014 Delta-9-THC Open study A treatment with oral THC was associated with significant decreases in agitation, as well as improvements in sleep duration and appetite.
Show Epilepsy Cannabis and other illicit drug use in epilepsy patients. Hamerle M, Ghaeni L, Kowski A, Weissinger F, Holtkamp M. 2014 Cannabis Survey The use of cannabis did not affect disease severity in epilepsy.
Show Pain A double-blind, placebo-controlled, crossover pilot trial with extension using an oral mucosal cannabinoid extract for treatment of chemotherapy-induced neuropathic pain. Lynch ME, Cesar-Rittenberg P, Hohmann AG. 2014 Cannabis Controlled study Reduction in pain intensity
Show Pain The subjective psychoactive effects of oral dronabinol studied in a randomized, controlled crossover clinical trial for pain. Issa MA, Narang S, Jamison RN, Michna E, Edwards RR, Penetar DM, Wasan AD. 2014 Cannabis;Delta-9-THC Controlled study Oral THC had similar psychoactive effects to smoked marijuana
Show Multiple sclerosis;Spasticity Effect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomised, placebo-controlled trial. Zajicek J, Ball S, Wright D, Vickery J, Nunn A, Miller D, Cano MG, McManus D, Mallik S, Hobart J; on behalf of the CUPID investigator group. 2013 Delta-9-THC Controlled study THC, which was given for 36 months, had no effect on progression compared to placebo
Show Dependency/withdrawal Impact of Cannabis Use during Stabilization on Methadone Maintenance Treatment. Scavone JL, Sterling RC, Weinstein SP, Van Bockstaele EJ. 2013 Cannabis Open study Objective ratings of opiate withdrawal decreased in patients using cannabis during stabilization
Show Cancer chemotherapy;Pain A Double-Blind, Placebo-Controlled, Crossover Pilot Trial With Extension Using an Oral Mucosal Cannabinoid Extract for Treatment of Chemotherapy-Induced Neuropathic Pain. Lynch ME, Cesar-Rittenberg P, Hohmann AG. 2013 Cannabis Controlled study Five patients tended to respond to a treatment with cannabis
Show Anxiety;Posttraumatic stress disorder Cannabidiol enhances consolidation of explicit fear extinction in humans. Das RK, Kamboj SK, Ramadas M, Yogan K, Gupta V, Redman E, Curran HV, Morgan CJ 2013 Cannabidiol Controlled study Cannabidiol enhances consolidation of fear extinction in humans.
Show Dependency/withdrawal Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report. Crippa JA, Hallak JE, Machado-de-Sousa JP, Queiroz RH, Bergamaschi M, Chagas MH, Zuardi AW. 2013 Cannabidiol Uncontrolled case report They were no major withdrawal symptoms.
Show Dependency/withdrawal Cannabis as a substitute for alcohol and other drugs: A dispensary-based survey of substitution effect in Canadian medical cannabis patients. Lucas P, Reiman A, Earleywine M, McGowan S, Oleson M, Coward M, Thomas B. 2013 Cannabis Survey Many patients substitute cannabis for alcohol, illegal and medicinal drugs
Show Psychosis/schizophrenia A controlled family study of cannabis users with and without psychosis. Proal AC, Fleming J, Galvez-Buccollini JA, Delisi LE. 2013 Cannabis Controlled study Cannabis does not cause psychosis by itself
Show Pain The Subjective Psychoactive Effects of Oral Dronabinol Studied in a Randomized, Controlled Crossover Clinical Trial For Pain. Issa MA, Narang S, Jamison RN, Michna E, Edwards RR, Penetar DM, Wasan AD. 2013 Cannabis;Delta-9-THC Controlled study In pain patients, oral dronabinol has similar psychoactive effects to smoking cannabis.
Show Cancer;Pain An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics Johnson JR, Lossignol D, Burnell-Nugent M, Fallon MT 2013 Cannabis Open study The cannabis extract Sativex was generally well tolerated, with no evidence of a loss of effect for pain relief.
Show Multiple sclerosis;Pain A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis. Langford RM, Mares J, Novotna A, Vachova M, Novakova I, Notcutt W, Ratcliffe S 2013 Cannabis Controlled study No significant difference between placebo and Sativex in Phase A; Phase B demonstrated an analgesic effect.
Show Gastrointestinal disorder;Inflammation;Pain Konikoff FM. Cannabis induces a clinical response in patients with Crohn’s disease: a prospective placebo-controlled study Naftali T, Bar-Lev Schleider L, Dotan I, Lansky EP, Sklerovsky Benjaminov F, Konikoff FM 2013 Cannabis Controlled study Cannabis produced significant clinical benefits in 10 of 11 patients with active Crohn’s disease.
Show Pain Low-dose vaporized cannabis significantly improves neuropathic pain Wilsey B, Marcotte T, Deutsch R, Gouaux B, Sakai S, Donaghe H 2013 Cannabis Controlled study Cannabis reduced pain. No difference in efficacy between the two doses.
Show Gastrointestinal disorder;Inflammation Marijuana Use Patterns Among Patients with Inflammatory Bowel Disease. Ravikoff Allegretti J, Courtwright A, Lucci M, Korzenik JR, Levine J. 2013 Cannabis Survey Patients find cannabis very helpful for symptom control.
Show Sleep disorder Around-the-clock oral THC effects on sleep in male chronic daily cannabis smokers. Gorelick DA, Goodwin RS, Schwilke E, Schroeder JR, Schwope DM, Kelly DL, Ortemann-Renon C, Bonnet D, Huestis MA. 2013 Delta-9-THC Open study Higher THC concentrations were significantly associated with less difficulty falling asleep and more daytime sleep the following day.
Show Cancer The medical necessity for medicinal cannabis: prospective, observational study evaluating the treatment in cancer patients on supportive or palliative care. Bar-Sela G, Vorobeichik M, Drawsheh S, Omer A, Goldberg V, Muller E. 2013 Cannabis Open study In an open clinical study with cancer patients all symptoms improved significantly.
Show HIV/AIDS Marijuana smoking does not accelerate progression of liver disease in HIV-hepatitis C coinfection: a longitudinal cohort analysis. Brunet L, Moodie EE, Rollet K, Cooper C, Walmsley S, Potter M, Klein MB; Canadian Co-infection Cohort Investigators. 2013 Cannabis Open study The use of cannabis did not accelerate progression to significant liver fibrosis.
Show Dependency/withdrawal Impact of cannabis use during stabilization on methadone maintenance treatment. Scavone JL, Sterling RC, Weinstein SP, Van Bockstaele EJ. 2013 Cannabis Open study Symptoms of opiate withdrawal decrease in patients undergoing methadone maintenance treatment, who use cannabis.
Show Multiple sclerosis Treatment failure of intrathecal baclofen and supra-additive effect of nabiximols in multiple sclerosis-related spasticity: a case report. Stroet A, Trampe N, Chan A. 2013 Cannabis Uncontrolled case report A combination of baclofen injections into the cerebrospinal fluid and very low doses of the cannabis extract Sativex was highly effective.
Show Pain Comparison of the analgesic effects of dronabinol and smoked marijuana in daily marijuana smokers. Cooper ZD, Comer SD, Haney M. 2013 Cannabis;Delta-9-THC Controlled study THC (dronabinol) and smoked cannabis (marijuana) caused similar effects on pain sensitivity and pain tolerance.
Show Dependency/withdrawal Nabilone decreases marijuana withdrawal and a laboratory measure of marijuana relapse. Haney M, Cooper ZD, Bedi G, Vosburg SK, Comer SD, Foltin RW. 2013 Nabilone Open study The use of nabilone reduced withdrawal symptoms.
Show Multiple sclerosis;Spasticity A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost-effectiveness in Germany. Flachenecker P. 2013 Cannabis Open study The cannabis extract sativex is effective in a large number of patients and well-tolerated in the long-term.
Show Multiple sclerosis;Spasticity Endocannabinoid system modulator use in everyday clinical practice in the UK and Spain. García-Merino A. 2013 Cannabis Open study Sativex appears to be a well-tolerated and useful add-on therapy in patients with spasticity due to multiple sclerosis.
Show Spasticity Proof of concept trial of dronabinol in obstructive sleep apnea. Prasad B, Radulovacki MG, Carley DW. 2013 Delta-9-THC Open study THC significantly improved this condition.
Show Headache/migraine Use of cannabis among 139 cluster headache sufferers. Leroux E, Taifas I, Valade D, Donnet A, Chagnon M, Ducros A. 2013 Cannabis Survey Less than one third of self-reported users mention a relief of their attacks following inhalation.
Show Dependency/withdrawal The dose effects of short-term dronabinol (oral THC) maintenance in daily cannabis users. Vandrey R, Stitzer ML, Mintzer MZ, Huestis MA, Murray JA, Lee D. 2013 Delta-9-THC Open study THC dose-dependently attenuated cannabis withdrawal.
Show Psychosis/schizophrenia Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia Leweke FM, Piomelli D, Pahlisch F, Muhl D, Gerth CW, Hoyer C, Klosterkötter J, Hellmich M, Koethe D. 2012 Cannabidiol Controlled study CBD was as effective as amisulpride, a standard antipsychotic
Show Multiple sclerosis;Pain;Spasticity Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial. Corey-Bloom J, Wolfson T, Gamst A, Jin S, Marcotte TD, Bentley H, Gouaux B. 2012 Cannabis Controlled study Smoked cannabis was superior to placebo in reducing spasticity and pain.
Show Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers. Martín-Santos R, Crippa JA, Batalla A, Bhattacharyya S, Atakan Z, Borgwardt S, Allen P, Seal M, Langohr K, Farré M, Zuardi AW, McGuire P. 2012 Delta-9-THC;Cannabidiol Controlled study CBD does not cause significant side effects
Show Pain Palmitoylethanolamide in the Treatment of Chronic Pain Caused by Different Etiopathogenesis. Gatti A, Lazzari M, Gianfelice V, Di Paolo A, Sabato E, Sabato AF. 2012 Other cannabinoids Open study Significant pain relief with palmitoylethanolamide (PEA)
Show Posttraumatic stress disorder Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence. Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. 2012 Cannabis Uncontrolled case report Significant improvement in one patient with PSD with cannabis
Show Pain An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee. Huggins JP, Smart TS, Langman S, Taylor L, Young T. 2012 Other cannabinoids Controlled study A FAAH inhibitor was not more effective than a placebo.
Show Pain Herbal cannabis use in patients labeled as fibromyalgia is associated with negative psychosocial parameters. Ste-Marie PA, Fitzcharles MA, Gamsa A, Ware MA, Shir Y. 2012 Cannabis Survey Many patients with fibromyalgia use cannabis products.
Show Pain;Spasticity Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report. Vicente-Valor MI, Garcia-Llopis P, Mejia Andujar L, Antonino de la Camara G, García Del Busto N, Lopez Tinoco M, Quintana Vergara B, Peiro Vilaplana C, Dominguez Moran JA, Sánchez Alcaraz A. 2012 Cannabis Uncontrolled case report The cannabis extract was effective in a patient with stiff person syndrome.
Show Traumatic brain injury Early Survival of Comatose Patients after Severe Traumatic Brain Injury with the Dual Cannabinoid CB1/CB2 Receptor Agonist KN38-7271: A Randomized, Double-Blind, Placebo-Controlled Phase II Trial. Firsching R, Piek J, Skalej M, Rohde V, Schmidt U, Striggow F; the KN38-7271 Study Group. 2012 Other cannabinoids Controlled study Survival rates within 1 month of the injury were significantly better.
Show Anxiety Effects of delta-9-tetrahydrocannabinol on evaluation of emotional images. Ballard ME, Bedi G, de Wit H. 2012 Delta-9-THC Controlled study THC renders fearful faces less fearful
Show Cancer;Pain Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial. Portenoy RK, Ganae-Motan ED, Allende S, Yanagihara R, Shaiova L, Weinstein S, McQuade R, Wright S, Fallon MT. 2012 Cannabis Controlled study Additional pain reduction following the two lower doses.
Show Posttraumatic stress disorder Mitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence. Passie T, Emrich HM, Karst M, Brandt SD, Halpern JH. 2012 Cannabis Uncontrolled case report Cannabis reduced course and intensity of symptoms.
Show Anxiety;Posttraumatic stress disorder Cannabinoid facilitation of fear extinction memory recall in humans. Rabinak CA, Angstadt M, Sripada CS, Abelson JL, Liberzon I, Milad MR, Phan KL. 2012 Delta-9-THC Controlled study THC prevented the recovery of fear in this experiment of extinction learning.
Show Multiple sclerosis;Pain;Spasticity A questionnaire survey of patients and carers of patients prescribed Sativex as an unlicensed medicine. Notcutt WG. 2012 Cannabis Survey Most respondents experienced improvements across a range of symptoms.
Show Multiple sclerosis;Pain;Spasticity Multiple Sclerosis and Extract of Cannabis: results of the MUSEC trial. Zajicek JP, Hobart JC, Slade A, Barnes D, Mattison PG; on behalf of the MUSEC Research Group. 2012 Cannabis Controlled study Significant improvement by the cannabis extract Cannador of spasticity and pain.
Show Pain Intractable neuropathic pain due to ulnar nerve entrapment treated with cannabis and ketamine 10%. Hesselink JM, Kopsky DJ. 2012 Cannabis Uncontrolled case report Significant pain improvement with cannabis and ketamine.
Show Pain Lack of effect of central nervous system-active doses of nabilone on capsaicin-induced pain and hyperalgesia. Kalliomäki J, Philipp A, Baxendale J, Annas P, Karlsten R, Segerdahl M. 2012 Nabilone Controlled study The cannabinoid had no significant effect on acute experimental pain.
Show Gastrointestinal disorder;Inflammation Impact of cannabis treatment on the quality of life, weight and clinical disease activity in inflammatory bowel disease patients: a pilot prospective study Lahat A, Lang A, Ben-Horin S 2012 Cannabis Open study Improvement in general health perception, social functioning, ability to work, physical pain and depression; weight gain; average rise in BMI; average Harvey-Bradshaw index was reduced
Show Appetite loss/weight loss;HIV/AIDS A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men Riggs PK, Vaida F, Rossi SS, Sorkin LS, Gouaux B, Grant I, Ellis RJ 2012 Cannabis Controlled study Cannabis administration was associated with significant increases in plasma levels of ghrelin and leptin, and decreases in PYY, but did not significantly influence insulin levels
Show Diarrhoea;Gastrointestinal disorder Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea Wong BS, Camilleri M, Eckert D, Carlson P, Ryks M, Burton D, Zinsmeister AR 2012 Delta-9-THC Controlled study THC had no significant effects on gut transit.
Show Epilepsy Seizure exacerbation in two patients with focal epilepsy following marijuana cessation. Hegde M, Santos-Sanchez C, Hess CP, Kabir AA, Garcia PA. 2012 Cannabis Uncontrolled case report Patients with epilepsy were able to control their seizures by the use of cannabis.
Show Pain A Randomized, Controlled Study to Investigate the Analgesic Efficacy of Single Doses of the Cannabinoid Receptor-2 Agonist GW842166, Ibuprofen or Placebo in Patients With Acute Pain Following Third Molar Tooth Extraction. Ostenfeld T, Price J, Albanese M, Bullman J, Guillard F, Meyer I, Leeson R, Costantin C, Ziviani L, Nocini PF, Milleri S. 2011 Other cannabinoids Controlled study No superior analgetic effect of the synthetic cannabinoid GW842166 over placebo.
Show Obsessive compulsive disorder Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study. Grant JE, Odlaug BL, Chamberlain SR, Kim SW. 2011 Delta-9-THC Open study Statistically significant reduction in symptom severity.
Show Increased Blood Pressure Following Abrupt Cessation of Daily Cannabis Use. Vandrey R, Umbricht A, Strain EC. 2011 Cannabis;Nabilone Survey In 6 of 13 subjects blood pressure increased significantly after cessation of cannabis use.
Show Appetite loss/weight loss;Cancer;Nausea/vomiting;Pain;Spasticity [Cannabinoids in children] [Article in German] Cannabinoide bei Kindern. Gottschling S. 2011 Delta-9-THC Uncontrolled case report Reduced pain, spasticity and improved appetite and nausea
Show Appetite loss/weight loss;Cancer Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial. Brisbois TD, de Kock IH, Watanabe SM, Mirhosseini M, Lamoureux DC, Chasen M, Macdonald N, Baracos VE, Wismer WV. 2011 Delta-9-THC Controlled study THC improved taste and appetite
Show Subjective and Physiological Effects After Controlled Sativex and Oral THC Administration. Karschner EL, Darwin WD, McMahon RP, Liu F, Wright S, Goodwin RS, Huestis MA. 2011 Cannabis;Delta-9-THC;Cannabidiol Controlled study Oral THC and the cannabis extract Sativex produced similar effects
Show Anxiety Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients. Bergamaschi MM, Queiroz RH, Chagas MH, de Oliveira DC, De Martinis BS, Kapczinski F, Quevedo J, Roesler R, Schröder N, Nardi AE, Martín-Santos R, Hallak JE, Zuardi AW, Crippa JA. 2011 Cannabidiol Controlled study Cannabidiol significamtly reduced anxiety.
Show Separate and combined effects of the cannabinoid agonists nabilone and Δ(9)-THC in humans discriminating Δ(9)-THC. Lile JA, Kelly TH, Hays LR. 2011 Delta-9-THC;Nabilone Controlled study THC caused similar effects as nabilone
Show Anxiety Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. Crippa JA, Derenusson GN, Ferrari TB, Wichert-Ana L, Duran FL, Martin-Santos R, Simões MV, Bhattacharyya S, Fusar-Poli P, Atakan Z, Santos Filho A, Freitas-Ferrari MC, McGuire PK, Zuardi AW, Busatto GF, Hallak JE. 2011 Cannabidiol Controlled study CBD reduces anxiety in patients with generalized social anxiety disorder.
Show The cannabinoid receptor agonist delta-9-tetrahydrocannabinol does not affect visceral sensitivity to rectal distension in healthy volunteers and IBS patients. Klooker TK, Leliefeld KE, Van Den Wijngaard RM, Boeckxstaens GE. 2011 Delta-9-THC Controlled study THC did not modify visceral perception to rectal distension.
Show Pain Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life. Fiz J, Durán M, Capellà D, Carbonell J, Farré M. 2011 Cannabis Open study The use of cannabis was associated with reduction of some fibromyalgia symptoms.
Show Cannabinoid effects on ventilation and breathlessness: A pilot study of efficacy and safety. Pickering EE, Semple SJ, Nazir MS, Murphy K, Snow TM, Cummin AR, Moosavi S, Guz A, Holdcroft A. 2011 Cannabis Controlled study With cannabis participants felt less breathless
Show Cancer Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas-possible role of Cannabis inhalation. Foroughi M, Hendson G, Sargent MA, Steinbok P. 2011 Cannabis Uncontrolled case report Spontaneous regression of benign brain tumour may have been associated with cannabis use.
Show Multiple sclerosis;Spasticity A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex(®) ), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis. Novotna A, Mares J, Ratcliffe S, Novakova I, Vachova M, Zapletalova O, Gasperini C, Pozzilli C, Cefaro L, Comi G, Rossi P, Ambler Z, Stelmasiak Z, Erdmann A, Montalban X, Klimek A, Davies P; the Sativex Spasticity Study Group. 2011 Cannabis Controlled study The cannabis extract significantly reduced spasticity.
Show Tourette’s syndrome Cannabinoids improve driving ability in a Tourette’s patient. Brunnauer A, Segmiller FM, Volkamer T, Laux G, Müller N, Dehning S 2011 Delta-9-THC Uncontrolled case report THC improved driving ability
Show Gastrointestinal disorder;Inflammation Cannabis use amongst patients with inflammatory bowel disease. Lal S, Prasad N, Ryan M, Tangri S, Silverberg MS, Gordon A, Steinhart H. 2011 Cannabis Survey Cannabis use is frequent in patients with chronic intestinal inflammation
Show Posttraumatic stress disorder Medical cannabis use in post-traumatic stress disorder: a naturalistic observational study. Reznik I. 2011 Cannabis Open study In most cases a significant improvement in quality of life and pain, with some positive changes in severity of posttraumatic stress disorder was observed.
Show The medicinal use of cannabis and cannabinoids: an international survey on methods of intake. Hazekamp A, Grotenhermen F, Abrams D, Russo E, Ware M, Navarrete-Varo R, Brenneisen R, Müller-Vahl K. 2011 Cannabis;Delta-9-THC;Nabilone Survey Preferred modes of use were smoking of cannabis (62.9 per cent), inhalation of cannabis with a vaporizer (23.6 per cent), oral use of cannabis in baked goods (7.9 per cent), oral use of cannabis as a tea (2.4 per cent), and oral use of dronabinol/Marinol (1.8 per cent).
Show Diarrhoea;Gastrointestinal disorder;Inflammation Treatment of Crohn’s disease with cannabis: an observational study. Naftali T, Lev LB, Yablekovitz D, Half E, Konikoff FM. 2011 Cannabis Open study Of the 30 patients 21 improved significantly
Show Diarrhoea;Gastrointestinal disorder Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients with Non-Constipated Irritable Bowel Syndrome. Wong BS, Camilleri M, Busciglio I, Carlson P, Szarka LA, Burton D, Zinsmeister AR. 2011 Delta-9-THC Controlled study Dronabinol reduces fasting motility of the colon in IBS patients with diarrhoea
Show HIV/AIDS A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men. Riggs PK, Vaida F, Rossi SS, Sorkin LS, Gouaux B, Grant I, Ellis RJ. 2011 Cannabis Controlled study Cannabis modulates the concentration of appetite hormones
Show Inflammation Impact of cannabis treatment on the quality of life, weight and clinical disease activity in inflammatory bowel disease patients: a pilot prospective study. Lahat A, Lang A, Ben-Horin S. 2011 Cannabis Open study Significant improvement of several symptoms.
Show Pain Cannabinoid-opioid interaction in chronic pain Abrams DI, Couey P, Shade SB, Kelly ME, Benowitz NL 2011 Cannabis Open study Pain was significantly decreased
Show Dependency/withdrawal Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial. Levin FR, Mariani JJ, Brooks DJ, Pavlicova M, Cheng W, Nunes EV 2011 Delta-9-THC Controlled study THC caused significant improvement in treatment retention and withdrawal symptoms.
Show Cancer Marijuana use is not associated with cervical human papillomavirus natural history or cervical neoplasia in HIV-seropositive or HIV-seronegative women. D’Souza G, Palefsky JM, Zhong Y, Minkoff H, Massad LS, Anastos K, Levine AM, Moxley M, Xue XN, Burk RD, Strickler HD. 2010 Cannabis Open study Cannabis use is not associated with cervical human papillomavirus natural history or cervical neoplasia in HIV-seropositive or HIV-seronegative women.
Show Nausea/vomiting Motion sickness, stress and the endocannabinoid system. Choukèr A, Kaufmann I, Kreth S, Hauer D, Feuerecker M, Thieme D, Vogeser M, Thiel M, Schelling G. 2010 Open study Volunteers who developed acute motion sickness (n = 7) showed lower endocannabinoid levels during parabolic flights.
Show Spasticity Tetrahydrocannabinol (THC) for cramps in amyotrophic lateral sclerosis: a randomised, double-blind crossover trial. Weber M, Goldman B, Truniger S. 2010 Delta-9-THC Controlled study There were no effects on cramp intensity, number of cramps and fasciculation intensity.
Show Tourette’s syndrome Oral Delta 9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: a case report. Hasan A, Rothenberger A, Münchau A, Wobrock T, Falkai P, Roessner V. 2010 Delta-9-THC Uncontrolled case report THC improved tics allowing parallel stimulant treatment of comorbid ADHD.
Show Appetite loss/weight loss Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis. Morgan CJ, Freeman TP, Schafer GL, Curran HV. 2010 Cannabis Open study Effects depended on the ratio of CBD and THC with high CBD reducing appetite enhancing effects of THC.
Show Spasticity;Spinal cord injury A randomized, double-blinded, crossover pilot study assessing the effect of nabilone on spasticity in persons with spinal cord injury. Pooyania S, Ethans K, Szturm T, Casey A, Perry D. 2010 Nabilone Controlled study There was a significant decrease in spasticity by nabilone.
Show Dystonia Tardive Dystonia and the Use of Cannabis. Beckmann Y, Seçil Y, Güngör B, Yiğit T. 2010 Cannabis;Delta-9-THC Uncontrolled case report Significant improvement by cannabis and dronabinol.
Show Dramatic improvement of refractory Isaacs’ syndrome after treatment with dronabinol. Meyniel C, Ollivier Y, Hamidou M, Péréon Y, Derkinderen P. 2010 Delta-9-THC Uncontrolled case report Dramathic improvement of symptoms (profuse sweating, muscular twitching, weight loss)
Show The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program. Villagonzalo KA, Dodd S, Ng F, Mihaly S, Langbein A, Berk M. 2010 Cannabis Survey Cannabis may be used to self-treat posttraumatic stress disorder (PTSD)
Show Improvement in refractory psychosis with dronabinol: four case reports. Schwarcz G, Karajgi B. 2010 Delta-9-THC Uncontrolled case report Significant improvement in four patients
Show Pain An Open-Label Comparison of Nabilone and Gabapentin as Adjuvant Therapy or Monotherapy in the Management of Neuropathic Pain in Patients with Peripheral Neuropathy. Bestard JA, Toth CC. 2010 Nabilone Open study The benefits of nabilone are similar as gabapentin
Show Nausea/vomiting;Cancer;Cancer chemotherapy Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting. Duran M, Pérez E, Abanades S, Vidal X, Saura C, Majem M, Arriola E, Rabanal M, Pastor A, Farré M, Rams N, Laporte JR, Capellà D. 2010 Cannabis Controlled study Cannabis was superior to placebo in reducing nausea and vomiting in patients refractory to other medications
Show Pain Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. Rintala DH, Fiess RN, Tan G, Holmes SA, Bruel BM. 2010 Delta-9-THC Controlled study No significant difference between THC and diphenhydramine.
Show Multiple sclerosis Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis. Kavia RB, De Ridder D, Constantinescu CS, Stott CG, Fowler CJ. 2010 Cannabis Controlled study The cannabis extract had some effect on overactive bladder symptoms.
Show Appetite loss/weight loss;HIV/AIDS Efficacy and tolerability of high-dose dronabinol maintenance in HIV-positive marijuana smokers: a controlled laboratory study. Bedi G, Foltin RW, Gunderson EW, Rabkin J, Hart CL, Comer SD, Vosburg SK, Haney M. 2010 Delta-9-THC Controlled study Tolerance developed to the appetite-increasing effects of THC.
Show Pain Smoked cannabis for chronic neuropathic pain: a randomized controlled trial. Ware MA, Wang T, Shapiro S, Robinson A, Ducruet T, Huynh T, Gamsa A, Bennett GJ, Collet JP. 2010 Cannabis Controlled study Cannabis improved pain and sleep quality.
Show Cancer;Pain Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study of the Efficacy, Safety, and Tolerability of THC:CBD Extract and THC Extract in Patients With Intractable Cancer-Related Pain. Johnson JR, Burnell-Nugent M, Lossignol D, Ganae-Motan ED, Potts R, Fallon MT. 2010 Cannabis;Delta-9-THC Controlled study A cannabis extract containing THC and CBD was superior in reducing pain than placebo.
Show Bipolar disorders Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia. Ringen PA, Vaskinn A, Sundet K, Engh JA, Jónsdóttir H, Simonsen C, Friis S, Opjordsmoen S, Melle I, Andreassen OA. 2010 Cannabis Survey In bipolar disorder subjects, cannabis use was associated with better neurocognitive function, but the opposite was the case for the schizophrenia subjects.
Show Pain Randomised Placebo Controlled Double Blind Clinical Trial of Cannabis Based Medicinal Product (Sativex) in Painful Diabetic Neuropathy: Depression is a Major Confounding Factor. Selvarajah D, Gandhi R, Emery CJ, Tesfaye S. 2010 Cannabis Controlled study No difference between cannabis extract and placebo.
Show Pain The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial. Ware MA, Fitzcharles MA, Joseph L, Shir Y. 2010 Nabilone Controlled study Improvement of sleep by nabilone.
Show PTSD contributes to teen and young adult cannabis use disorders. Cornelius JR, Kirisci L, Reynolds M, Clark DB, Hayes J, Tarter R. 2010 Cannabis Survey People with PTSD have a higher risk for cannabis use
Show Pain Adjuvant topical therapy with a cannabinoid receptor agonist in facial postherpetic neuralgia. Phan NQ, Siepmann D, Gralow I, Ständer S. 2010 Other cannabinoids Open study Five of eight patients experienced a good pain relief
Show Multiple sclerosis;Spasticity A double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis Collin C, Ehler E, Waberzinek G, Alsindi Z, Davies P, Powell K, Notcutt W, O’Leary C, Ratcliffe S, Nováková I, Zapletalova O, Piková J, Ambler Z 2010 Cannabis Controlled study Significant reduction in treatment-resistant spasticity.
Show HIV/AIDS;Pain Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial. Ellis RJ, Toperoff W, Vaida F, van den Brande G, Gonzales J, Gouaux B, Bentley H, Atkinson JH. 2009 Cannabis Controlled study Significant pain relief with cannabis.
Show Treatment of a hyperkinetic movement disorder during pregnancy with dronabinol. Farooq MU, Ducommun E, Goudreau J. 2009 Delta-9-THC Uncontrolled case report Improvement of her hyperkinetic movement disorder with no signs of tolerance
Show Effect of Delta(9)-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans. Beaumont H, Jensen J, Carlsson A, Ruth M, Lehmann A, Boeckxstaens GE. 2009 Delta-9-THC Controlled study THC reduced acid reflux episodes in the first hour after a meal.
Show Multiple sclerosis Psychopathological and cognitive effects of therapeutic cannabinoids in multiple sclerosis: a double-blind, placebo controlled, crossover study. Aragona M, Onesti E, Tomassini V, Conte A, Gupta S, Gilio F, Pantano P, Pozzilli C, Inghilleri M. 2009 Cannabis Controlled study Cannabis did not impair cognition
Show Nausea/vomiting;HIV/AIDS;Pain;Depression;Anxiety Marijuana Effectiveness as an HIV Self-Care Strategy. Corless IB, Lindgren T, Holzemer W, Robinson L, Moezzi S, Kirksey K, Coleman C, Tsai YF, Sanzero Eller L, Hamilton MJ, Sefcik EF, Canaval GE, Rivero Mendez M, Kemppainen JK, Bunch EH, Nicholas PK, Nokes KM, Dole P, Reynolds N. 2009 Cannabis Survey Participants rated cannabis as similar effective as other medications for the treatment of their symptoms.
Show Relief oriented use of marijuana by teens. Bottorff JL, Johnson JL, Moffat BM, Mulvogue T. 2009 Cannabis Survey 20 participants said that they used cannabis to treat health problems.
Show Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism. Trevaskis NL, Shackleford DM, Charman WN, Edwards GA, Gardin A, Appel-Dingemanse S, Kretz O, Galli B, Porter CJ. 2009 Other cannabinoids Controlled study Systemic bioavailability of the cannabinoid CRA13 increased by more than 4-fold if taken together with a fat-rich meal.
Show Headache/migraine Cluster attacks responsive to recreational cannabis and dronabinol. Robbins MS, Tarshish S, Solomon S, Grosberg BM. 2009 Cannabis;Delta-9-THC Uncontrolled case report Cannabis and THC aborted attacks of headaches.
Show Dependency/withdrawal Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependence. Raby WN, Carpenter KM, Rothenberg J, Brooks AC, Jiang H, Sullivan M, Bisaga A, Comer S, Nunes EV 2009 Cannabis Open study Better adherence to natrexone therapy with intermittend cannabis use
Show Synthetic delta-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia. Schwarcz G, Karajgi B, McCarthy R. 2009 Cannabis Open study Improvement in 4 of 6 participants, of whom 3 showed a significant improvement.
Show Spasticity;Multiple sclerosis Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. Centonze D, Mori F, Koch G, Buttari F, Codecà C, Rossi S, Cencioni MT, Bari M, Fiore S, Bernardi G, Battistini L, Maccarrone M. 2009 Cannabis Controlled study There was no effect of the cannabis extract on spasticity
Show Spasticity;Pain Reposition of a dislocated shoulder under use of cannabis. Schweizer A, Bircher HP. 2009 Cannabis Uncontrolled case report Pain and muscular tone decreased and the shoulder was relocated easily.
Show Dependency/withdrawal White matter integrity in adolescents with histories of marijuana use and binge drinking. Jacobus J, McQueeny T, Bava S, Schweinsburg BC, Frank LR, Yang TT, Tapert SF. 2009 Cannabis Open study Brain damage was less in alcohol users who used also cannabis than in alcohol only users.
Show Dependency/withdrawal Cannabis as a substitute for alcohol and other drugs Reiman A. 2009 Cannabis Survey 40 % use cannabis to substitute for alcohol, 26 % to substitute for illegal drugs
Show Pain Characteristics of patients with chronic pain accessing treatment with medical cannabis in Washington State. Aggarwal SK, Carter GT, Sullivan MD, ZumBrunnen C, Morrill R, Mayer JD. 2009 Cannabis Open study 88 % suffer from more than one pain syndrome
Show Cancer A population-based case-control study of marijuana use and head and neck squamous cell carcinoma. Liang C, McClean MD, Marsit C, Christensen B, Peters E, Nelson HH, Kelsey KT. 2009 Cannabis Survey Subjects who used cannabis had a reduced cancer risk.
Show Multiple sclerosis;Pain Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis. Conte A, Bettolo CM, Onesti E, Frasca V, Iacovelli E, Gilio F, Giacomelli E, Gabriele M, Aragona M, Tomassini V, Pantano P, Pozzilli C, Inghilleri M. 2009 Cannabis Controlled study The study provides objective neurophysiological evidence that cannabinoids modulate the nociceptive system.
Show Nausea/vomiting Use of medical marijuana for treatment of severe intractable nausea after laparoscopic Roux-en-Y gastric bypass surgery: case report. Merriman AR, Oliak DA. 2008 Delta-9-THC Uncontrolled case report THC relieved nausea refractory to other medications
Show Pain Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study. Frank B, Serpell MG, Hughes J, Matthews JN, Kapur D. 2008 Nabilone Controlled study Nabilone as effective as hydrocodeine in treating neuropatic pain
Show Nausea/vomiting;Appetite loss/weight loss Evaluation of oral cannabinoid-containing medications for the management of interferon and ribavirin-induced anorexia, nausea and weight loss in patients treated for chronic hepatitis C virus. Costiniuk CT, Mills E, Cooper CL 2008 Delta-9-THC;Nabilone Open study Improvement of appetite and reduction of nausea and vomiting by nabilone and dronabinol (THC)
Show Appetite loss/weight loss;Cancer;Pain Adjunctive nabilone in cancer pain and symptom management: a prospective observational study using propensity scoring. Maida V, Ennis M, Irani S, Corbo M, Dolzhykov M. 2008 Nabilone Open study Significant improvement of pain
Show Pain A Randomized, Placebo-Controlled, Crossover Trial of Cannabis Cigarettes in Neuropathic Pain. Wilsey B, Marcotte T, Tsodikov A, Millman J, Bentley H, Gouaux B, Fishman S. 2008 Cannabis Controlled study Significant improvement of pain
Show Improvement in refractory obsessive compulsive disorder with dronabinol. Schindler F, Anghelescu I, Regen F, Jockers-Scherubl M. 2008 Delta-9-THC Uncontrolled case report Significant symptom improvement
Show Multiple sclerosis;Dystonia Current status of cannabis treatment of multiple sclerosis with an illustrative case presentation of a patient with MS, complex vocal tics, paroxysmal dystonia, and marijuana dependence treated with dronabinol. Deutsch SI, Rosse RB, Connor JM, Burket JA, Murphy ME, Fox FJ. 2008 Delta-9-THC Open study Significant improvement of symptoms
Show Pain Lack of analgesia by oral standardized cannabis extract on acute inflammatory pain and hyperalgesia in volunteers. Kraft B, Frickey NA, Kaufmann RM, Reif M, Frey R, Gustorff B, Kress HG. 2008 Cannabis Controlled study The cannabis extract showed no analgesic effect in acute experimental pain
Show Pain Analgesic and antihyperalgesic effects of nabilone on experimental heat pain. Redmond WJ, Goffaux P, Potvin S, Marchand S. 2008 Nabilone Controlled study Nabilone did not reduce experimental heat pain
Show Alzheimer’s disease The cannabinoid receptor agonist nabilone for the treatment of dementia-related agitation. Passmore MJ. 2008 Nabilone Uncontrolled case report Dramatic reduction in the severity of agitation and other behavioural symptoms
Show Dependency/withdrawal Use of dronabinol for cannabis dependence: two case reports and review. Levin FR, Kleber HD. 2008 Delta-9-THC Uncontrolled case report THC reduced withdrawal symptoms in cannabis dependence
Show Pain Nabilone for the treatment of pain in fibromyalgia. Skrabek RQ, Galimova L, Ethans K, Perry D. 2008 Nabilone Controlled study Nabilone improved symptoms and was well-tolerated
Show Pain Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy. Narang S, Gibson D, Wasan AD, Ross EL, Michna E, Nedeljkovic SS, Jamison RN. 2008 Delta-9-THC Controlled study THC reduced pain
Show Cancer Nabilone for the treatment of paraneoplastic night sweats: a report of four cases. Maida V. 2008 Nabilone Open study Significant improvement of night sweats within 2 days
Show Pain A prospective identification of neuropathic pain in specific chronic polyneuropathy syndromes and response to pharmacological therapy. Toth C, Au S. 2008 Cannabis;Nabilone Open study Similar treatment effects and side effects of cannabinoids compared to other medications
Show Pain Open-label, add-on study of tetrahydrocannabinol for chronic nonmalignant pain. Haroutiunian S, Rosen G, Shouval R, Davidson E. 2008 Delta-9-THC Open study 5 patients reported adequate response to the treatment.
Show Epilepsy Marijuana: an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature. Mortati K, Dworetzky B, Devinsky O. 2007 Cannabis Uncontrolled case report Significant improvement of epilepsy with the use of cannabis.
Show Pain Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. Wallace M, Schulteis G, Atkinson JH, Wolfson T, Lazzaretto D, Bentley H, Gouaux B, Abramson I. 2007 Cannabis Controlled study A medium dose of cannabis reduced pain, while a high dose increased pain induced by capsaicin
Show Multiple sclerosis;Pain Oromucosal ∆9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial. Rog DJ, Nurmikko TJ, Young CA. 2007 Cannabis Open study No development of tolerance within a period of two years of treatment
Show [Fitness to drive in spite (because) of THC] [Article in German] Strohbeck-Kühner P, Skopp G, Mattern R. 2007 Cannabis Uncontrolled case report Significant improvement of driving-related performance
Show Pain Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial. Nurmikko TJ, Serpell MG, Hoggart B, Toomey PJ, Morlion BJ, Haines D. 2007 Cannabis Controlled study Significant improvement in pain by cannabis
Show Vaporization as a smokeless cannabis delivery system: a pilot study. Abrams DI, Vizoso HP, Shade SB, Jay C, Kelly ME, Benowitz NL 2007 Cannabis Controlled study;Basic research Vaporization of cannabis is a safe and effective mode of delivery of THC
Show Appetite loss/weight loss Anorexia of aging in long term care: is dronabinol an effective appetite stimulant? – a pilot study. Wilson MM, Philpot C, Morley JE 2007 Delta-9-THC Open study A trend towards weight gain
Show Nausea/vomiting;Appetite loss/weight loss;HIV/AIDS THC improves appetite and reverses weight loss in AIDS patients Dejesus E, Rodwick BM, Bowers D, Cohen CJ, Pearce D 2007 Delta-9-THC Open study THC improved appetite and weight and reduced nausea
Show Appetite loss/weight loss;HIV/AIDS Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep. Haney M, Gunderson EW, Rabkin J, Hart CL, Vosburg SK, Comer SD, Foltin RW 2007 Cannabis;Delta-9-THC Controlled study THC and cannabis caused an increase in caloric intake and weight
Show Nausea/vomiting;Cancer;Cancer chemotherapy Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. Meiri E, Jhangiani H, Vredenburgh JJ, Barbato LM, Carter FJ, Yang HM, Baranowski V. 2007 Delta-9-THC Controlled study Dronabinol was as effective as ondansetron in reducing nausea and vomiting. Combination therapy was not more effective.
Show Spasticity;Multiple sclerosis Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis Collin C, Davies P, Mutiboko IK, Ratcliffe S, for the Sativex Spasticity in MS Study Group 2007 Cannabis Controlled study Significantly reduction in spasticity
Show HIV/AIDS;Pain Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial. Abrams DI, Jay CA, Shade SB, Vizoso H, Reda H, Press S, Kelly ME, Rowbotham MC, Petersen KL. 2007 Cannabis Controlled study Smoked cannabis was well tolerated and effectively relieved chronic neuropathic pain from HIV-associated sensory neuropathy.
Show Glaucoma Dronabinol and retinal hemodynamics in humans. Plange N, Arend KO, Kaup M, Doehmen B, Adams H, Hendricks S, Cordes A, Huth J, Sponsel WE, Remky A. 2007 Delta-9-THC Open study THC reduced intraoculat pressure and improved blood circulation in the retina.
Show Pain Nabilone for the treatment of pain in fibromyalgia. Skrabek RQ, Galimova L, Ethansand Daryl K. 2007 Nabilone Controlled study Significant reduction of pain and improvement of quality of life with nabilone
Show Pain Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy Narang S, Gibson D, Wasan AD, Ross EL, Michna E, Nedeljkovic SS, Jamison RN 2007 Delta-9-THC Controlled study;Open study THC had an additional effect on pain relief
Show Spasticity;Spinal cord injury;Pain Sativex® in the Treatment of Central Neuropathic Pain due to Spinal Cord Injury: A Randomised Controlled Study Berman J & the Sativex Spinal Cord Injury Study Group, Bosworth T2 Guy G & Stott C. 2007 Cannabis Controlled study primary outcome mean NRS 11 poitn pain scale – nod difference – BPI secondary ourcome benefit – significant at p<0.032
Show Effects of a cannabinoid receptor agonist on colonic motor and sensory functions in humans: a randomized, placebo-controlled study. Esfandyari T, Camilleri M, Busciglio I, Burton D, Baxter K, Zinsmeister AR. 2007 Delta-9-THC Controlled study THC relaxes the colon and reduces postprandial colonic motility
Show Cancer;Cancer chemotherapy Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel. Engels FK, de Jong FA, Sparreboom A, Mathot RA, Loos WJ, Kitzen JJ, de Bruijn P, Verweij J, Mathijssen RH. 2007 Cannabis Open study Cannabis did not influence the pharmacokinetics of the two anti-cancer drugs
Show Bipolar disorders The effect of extreme marijuana use on the long-term course of bipolar I illness: a single case study. El-Mallakh RS, Brown C. 2007 Cannabis Uncontrolled case report Cannabis decreased the number of depressed days and increased the number of hypomanic days.
Show Multiple sclerosis Cannabis; adverse effects from an oromucosal spray. Scully C. 2007 Cannabis Open study The spray caused reversible damage to the mucosa
Show Long term marijuana users seeking medical cannabis in California (2001-2007): demographics, social characteristics, patterns of cannabis and other drug use of 4117 applicants. O’Connell TJ, Bou-Matar CB. 2007 Cannabis Survey
Show Spasticity;Spinal cord injury The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury. Hagenbach U, Luz S, Ghafoor N, Berger JM, Grotenhermen F, Brenneisen R, Mader M. 2006 Delta-9-THC Open study Significant improvement of spasticity with THC
Show Multiple sclerosis Randomised controlled study of cannabis-based medicine (Sativex®) in patients suffering from multiple sclerosis associated detrusor overactivity de Ridder D, Constantinescu CS,Fowler C, Kavia R, Sarantis N. 2006 Cannabis Controlled study A significant reduction in the number of voids per day and during the night.
Show Spasticity;Multiple sclerosis A randomised controlled study of Sativex® in patients with symptoms of spasticity due to multiple sclerosis Collin C, Ambler Z, Kent R, McCalla R. 2006 Cannabis Controlled study Spasticity of patients who received cannabis and complied with the study protocol was significantly reduced compared to placebo.
Show Nausea/vomiting;Appetite loss/weight loss;Cancer;Pain;Depression;Anxiety The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients Maida V. 2006 Nabilone Open study Nabilone treatment improved pain, nausea, appetite and several other symptoms
Show Pain Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine. Roberts JD, Gennings C, Shih M. 2006 Delta-9-THC Controlled study There was a synergistic effect between THC and morphine on the affective component of pain but not on the sensory component
Show Pain [(9)-tetrahydrocannabinol and the opioid receptor agonist piritramide do not act synergistically in postoperative pain.] [Article in German] Seeling W, Kneer L, Buchele B, Gschwend JE, Maier L, Nett C, Simmet T, Steffen P, Schneider M, Rockemann M. 2006 Delta-9-THC Controlled study Application of THC reduced the need of an opioid to treat postoperative pain but the difference to placebo was not significant
Show Nausea/vomiting;Appetite loss/weight loss;Cancer;Cancer chemotherapy [Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.] [Article in German] Zutt M, Hanssle H, Emmert S, Neumann C, Kretschmer L. 2006 Delta-9-THC Open study A significant increase in appetite and decrease in nausea in most patients.
Show Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension: a case report. Raby WN, Modica PA, Wolintz RJ, Murtaugh K. 2006 Cannabis;Delta-9-THC Uncontrolled case report Improvement of signs and symptoms of the disease
Show Cannabidiol monotherapy for treatment-resistant schizophrenia Zuardi AW, Hallak JE, Dursun SM, Morais SL, Faria Sanches R, Musty RE, Crippa JA. 2006 Cannabidiol Open study CBD monotherapy was not effective in treatment-resistant schizophrenia
Show Alzheimer’s disease Delta-9-tetrahydrocannabinol for night-time agitation in severe dementia Walther S, Mahlberg R, Eichmann U, Kunz D 2006 Delta-9-THC Open study Reduction in night-time agitation in actigraphy and in the neuropsychiatric inventory NPI
Show Pain A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract (Cannador) for postoperative pain management. Holdcroft A, Maze M, Dore C, Tebbs S, Thompson S. 2006 Cannabis Controlled study The optimal dose was 10 mg Cannador, effectively reducing postoperative pain without serious side effects.
Show Multiple sclerosis The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS). Freeman RM, Adekanmi O, Waterfield MR, Waterfield AE, Wright D, Zajicek J. 2006 Cannabis;Delta-9-THC Controlled study Cannabis and dronabinol caused a significant reduction in incontinence
Show Spasticity;Spinal cord injury [Respiratory failure due to delta-9-tetrahydrocannabinol in a tetraplegic patient.]. [Article in German] Neuburger M, Schley M, Schmelz M, Schuepfer G, Konrad C. 2006 Delta-9-THC Uncontrolled case report Dronabinol reduced spasticity but worsened respiration
Show Cancer A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Guzman M, Duarte MJ, Blazquez C, Ravina J, Rosa MC, Galve-Roperh I, Sanchez C, Velasco G, Gonzalez-Feria L. 2006 Delta-9-THC Open study THC was well tolerated in this pilot study of intrakranial cannabinoid administration
Show Pain Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief. Schley M, Legler A, Skopp G, Schmelz M, Konrad C, Rukwied R. 2006 Delta-9-THC Open study Five of the nine patients withdrew from the study due to side effects. Four patients experienced significant pain relief
Show Appetite loss/weight loss;Cancer Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-in-Cachexia-Study-Group Strasser F, Luftner D, Possinger K, Ernst G, Ruhstaller T, Meissner W, Ko YD, Schnelle M, Reif M, Cerny T. 2006 Cannabis;Delta-9-THC Controlled study No difference between cannabis, THC and placebo
Show [Topical cannabinoid agonists : An effective new possibility for treating chronic pruritus.] [Article in German] Stander S, Reinhardt HW, Luger TA. 2006 Other cannabinoids Open study Topical application of a cream with N-palmitoyl ethanolamine had a good antipruritic effect in most patients.
Show Pain [Benefits of an add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain – a randomized controlled trial.] [Article in German] Pinsger M, Schimetta W, Volc D, Hiermann E, Riederer F, Polz W. 2006 Nabilone Controlled study Nabilone caused a significant reduction in pain and improvement of quality of life.
Show Pain Effects of nabilone, a synthetic cannabinoid, on postoperative pain. Beaulieu P. 2006 Nabilone Controlled study No pain reduction with nabilone.
Show Multiple sclerosis;Pain Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial. Wissel J, Haydn T, Muller J, Brenneis C, Berger T, Poewe W, Schelosky LD. 2006 Nabilone Controlled study Significant reduction of pain
Show Glaucoma Effect of Sublingual Application of Cannabinoids on Intraocular Pressure: A Pilot Study. Tomida I, Azuara-Blanco A, House H, Flint M, Pertwee RG, Robson PJ. 2006 Delta-9-THC;Cannabidiol Controlled study Significant reduction of intraocular pressure
Show Nausea/vomiting;Cancer chemotherapy;Pain Cannabinoids in the management of intractable chemotherapy-induced nausea and vomiting and cancer-related pain. Sutton IR, Daeninck P. 2006 Nabilone Survey;Uncontrolled case report Significant improvement in one case of intractable neuropathic pain and one case of refractory cinv
Show Pain Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Blake DR, Robson P, Ho M, Jubb RW, McCabe CS. 2006 Cannabis Controlled study Cannabis produced improvements in pain and sleep
Show Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial. Maas AI, Murray G, Henney H 3rd, Kassem N, Legrand V, Mangelus M, Muizelaar JP, Stocchetti N, Knoller N; Pharmos TBI investigators. 2006 Other cannabinoids Controlled study No effect of dexanabinol
Show Nausea/vomiting Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against ‘morning sickness’. Westfall RE, Janssen PA, Lucas P, Capler R. 2006 Cannabis Survey Cannabis effective against nausea and vomiting
Show Pain Experience with the synthetic cannabinoid nabilone in chronic noncancer pain. Berlach DM, Shir Y, Ware MA. 2006 Nabilone Open study 9 patients reported reduced pain intensity
Show Nausea/vomiting Prevention of nausea and vomiting following breast surgery. Layeeque R, Siegel E, Kass R, Henry-Tillman RS, Colvert M, Mancino A, Klimberg VS. 2006 Delta-9-THC Open study Postoperative nausea and vomiting was reduced by prophylactic administration of dronabinol and prochlorperazine
Show Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study. Esfandyari T, Camilleri M, Ferber I, Burton D, Baxter K, Zinsmeister AR. 2006 Delta-9-THC Controlled study THC retarded gastric emptying
Show Nausea/vomiting Cannabis use improves retention and virological outcomes in patients treated for hepatitis C. Sylvestre DL, Clements BJ, Malibu Y. 2006 Cannabis Open study Participants who used cannabis maintained adherence to treatment more offen
Show Spasticity;Multiple sclerosis;Pain Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. Wade DT, Makela PM, House H, Bateman C, Robson P. 2006 Cannabis Open study Long-term use of cannabis maintains its therapeutic effects
Show Spasticity;Multiple sclerosis;Pain Cannabis use in patients with multiple sclerosis. Chong MS, Wolff K, Wise K, Tanton C, Winstock A, Silber E. 2006 Cannabis Survey A subgroup of patients with severe disabilitiy appears to derive some benefit
Show Pain Evaluation of herbal cannabis characteristics by medical users: a randomized trial. Ware MA, Ducruet T, Robinson AR. 2006 Cannabis Controlled study Medical cannabis users can appreciate differences in herbal cannabis products
Show Dependency/withdrawal Concurrent cannabis use during treatment for comorbid ADHD and cocaine dependence: effects on outcome. Aharonovich E, Garawi F, Bisaga A, Brooks D, Raby WN, Rubin E, Nunes EV, Levin FR. 2006 Cannabis Open study Moderate cannabis use had a positive effect of retention rates and abstinence from cocaine
Show Spasticity;Multiple sclerosis Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up. Zajicek JP, Sanders HP, Wright DE, Vickery PJ, Ingram WM, Reilly SM, Nunn AJ, Teare LJ, Fox PJ, Thompson AJ. 2005 Cannabis;Delta-9-THC Controlled study Spasticity in the Ashworth scale was significantly reduced by an average of 1.82 in the THC group; no significant reduction in the cannabis group
Show Spasticity;Multiple sclerosis Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. Robson P, Wade D, Makela P, House H, Bateman C 2005 Cannabis Controlled study Beneficial effects of cannabis on spasticity in MS seem to be maintained over long-term treatment, with no evidence of tolerance.
Show HIV/AIDS;Pain Smoked cannabis therapy for HIV-related painful peripheral neuropathy: results of a randomized, placebo-controlled clinical trial. Abrams DI, Jay CA, Vizoso H, Shade SB, Reda H, Press S, Kelly ME, Rowbotham M, Petersen K 2005 Cannabis Controlled study Smoked cannabis is effective in reducing HIV-related neuropathic pain
Show Epilepsy Treatment with CBD in oily solution of drug-resistant paediatric epilepsies. Pelliccia A, Grassi G, Romano A, Crocchialo P 2005 Cannabidiol Open study Improvement of epilepsy without side effects
Show Pain Standardized cannabis extract in the treatment of postherpetic neuralgia – a randomized, double-blind, placebo-controlled cross-over study. Ernst G, Denke C, Reif M, Schnelle M, Hagmeister H 2005 Cannabis Controlled study Cannabis did not reduce pain
Show Multiple sclerosis;Pain Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Rog DJ, Nurmikko TJ, Friede T, Young CA. 2005 Cannabis Controlled study Cannabis is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain
Show Nausea/vomiting;HIV/AIDS Marijuana use and its association with adherence to antiretroviral therapy among HIV-infected persons with moderate to severe nausea. de Jong BC, Prentiss D, McFarland W, Machekano R, Israelski DM. 2005 Cannabis Open study Cannabis improved adherence to antiretroviral therapy in HIV/AIDS
Show Appetite loss/weight loss;HIV/AIDS;Alzheimer’s disease Dronabinol and marijuana in HIV(+) marijuana smokers: acute effects on caloric intake and mood. Haney M, Rabkin J, Gunderson E, Foltin RW. 2005 Cannabis;Delta-9-THC Controlled study THC and cannabis cause increased caloric intake
Show Appetite loss/weight loss Dronabinol – eine mögliche neue Therapieoption bei COPD-Patienten mit pulmonaler Kachexie [Dronabinol, a possible new therapeutic option in patients with COPD and pulmonal cachexia] Bergmann K-C 2005 Delta-9-THC Open study On average 1,5 kg of weight gain and increase of walking distance
Show Nausea/vomiting;Appetite loss/weight loss;HIV/AIDS;Pain;Anxiety Cannabis use in HIV for pain and other medical symptoms. Woolridge E, Barton S, Samuel J, Osorio J, Dougherty A, Holdcroft A. 2005 Cannabis Survey 27% used cannabis for the treatment of various symptoms
Show Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction. D’Souza DC, Abi-Saab WM, Madonick S, Forselius-Bielen K, Doersch A, Braley G, Gueorguieva R, Cooper TB, Krystal JH. 2005 Delta-9-THC Controlled study THC is associated with transient exacerbation in core psychotic and cognitive deficits in schizophrenia.
Show Pain;Depression;Anxiety Cannabis use in sickle cell disease: a questionnaire study. Howard J, Anie KA, Holdcroft A, Korn S, Davies SC. 2005 Cannabis Survey 36% had used cannabis to treat symptoms
Show Dependency/withdrawal Low efficacy of non-opioid drugs in opioid withdrawal symptoms. Hermann D, Klages E, Welzel H, Mann K, Croissant B. 2005 Cannabis Survey Only low efficacy of cannabis in alleviating opioid withdrawal symptoms
Show Efficacy and tolerance of the cream containing structured physiological lipids with endocannabinoids in the treatment of uremic pruritus: a preliminary study. Szepietowski JC, Szepietowski T, Reich A. 2005 Other cannabinoids Open study Improvement of pruritus with the cream
Show The medicinal use of cannabis in the UK: results of a nationwide survey. Ware MA, Adams H, Guy GW. 2005 Cannabis Survey Cannabis use was reported by 25 % of patients with chronic pain and 22 % of patients with multiple sclerosis
Show Clinical improvement and reduction of immunosuppressive drug therapy in cannabis treated patients with crohn’s disease. Hergenrather JY, Mikuriya TH, Bearman D. 2005 Cannabis Survey The majority of patients found a substantial improvement of their symptoms
Show Multiple sclerosis Cannabinoid influence on cytokine profile in multiple sclerosis. Katona S, Kaminski E, Sanders H, Zajicek J. 2005 Cannabis;Delta-9-THC Controlled study There were no significant effects of cannabinoids on the cytokine profiles examined.
Show Pain Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. Berman JS, Symonds C, Birch R. 2004 Cannabis;Delta-9-THC Controlled study Significant pain relief and improvement of sleep
Show Parkinson’s disease Cannabis for dyskinesia in Parkinson disease: a randomized double-blind crossover study. Carroll CB, Bain PG, Teare L, Liu X, Joint C, Wroath C, Parkin SG, Fox P, Wright D, Hobart J, Zajicek JP. 2004 Cannabis Controlled study Cannabis had no treatment effect on levodopa-induced dyskinesia.
Show Parkinson’s disease Survey on cannabis use in Parkinson’s disease: subjective improvement of motor symptoms. Venderova K, Ruzicka E, Vorisek V, Visnovsky P. 2004 Cannabis Survey 25% of the respondents had taken cannabis and 45.9% of these described some form of benefit.
Show Multiple sclerosis;Pain Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial Svendsen KB, Jensen TS, Bach FW 2004 Delta-9-THC Controlled study Significant reduction of pain by THC
Show Spasticity;Multiple sclerosis;Pain;Tremor Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Wade DT, Makela P, Robson P, House H, Bateman C. 2004 Cannabis Controlled study Spasticity scores were significantly reduced by cannabis.
Show Spasticity;Multiple sclerosis Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy.Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. Vaney C, Heinzel-Gutenbrunner M, Jobin P, Tschopp F, Gattlen B, Hagen U, Schnelle M, Reif M. 2004 Cannabis Controlled study Significant reduction in spasm frequency in the 37 patients who received at least 90% of the dose.
Show Multiple sclerosis An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Brady CM, DasGupta R, Dalton C, Wiseman OJ, Berkley KJ, Fowler CJ. 2004 Cannabis Open study Urinary urgency, the number and volume of incontinence episodes, frequency and nocturia all decreased.
Show Multiple sclerosis;Tremor The effect of cannabis on tremor in patients with multiple sclerosis. Fox P, Bain PG, Glickman S, Carroll C, Zajicek J. 2004 Cannabis;Delta-9-THC;Other cannabinoids Controlled study No significant improvement of tremor
Show Pain Are oral cannabinoids safe and effective in refractory neuropathic pain? Attal N, Brasseur L, Guirimand D, Clermond-Gnamien S, Atlami S, Bouhassira D 2004 Delta-9-THC Open study No significant decraese of pain in 7 patients, more than 60% decrease in one patient
Show Dependency/withdrawal Marijuana withdrawal in humans: effects of oral THC or divalproex. Haney M, Hart CL, Vosburg SK, Nasser J, Bennett A, Zubaran C, Foltin RW. 2004 Delta-9-THC Controlled study THC abolished withdrawal symptoms
Show Appetite loss/weight loss;HIV/AIDS;Pain;Depression Patterns of marijuana use among patients with HIV/AIDS followed in a public health care setting. Prentiss D, Power R, Balmas G, Tzuang G, Israelski DM. 2004 Cannabis Survey Improvement of pain, appetite and depression/anxiety by using cannabis
Show Appetite loss/weight loss;Spasticity;Pain;Depression Survey of cannabis use in patients with amyotrophic lateral sclerosis. Amtmann D, Weydt P, Johnson KL, Jensen MP, Carter GT. 2004 Cannabis Survey Moderate improvement of pain, spasticity, appetite and depression
Show Pain Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 ‘N of 1’ studies. Notcutt W, Price M, Miller R, Newport S, Phillips C, Simmons S, Sansom C. 2004 Cannabis Controlled study Improvement of pain
Show Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults. Nicholson AN, Turner C, Stone BM, Robson PJ. 2004 Cannabis;Delta-9-THC;Cannabidiol Controlled study THC had sedative effects, CBD had alerting effects
Show Cannabis improves night vision: A pilot study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif Mountains of Northern Morocco. Russo EB, Merzouki A, Molero Mesa J, Frey KA, Bach PJ. 2004 Cannabis;Delta-9-THC Controlled study Oral THC and smoking of cannabis improved night vision
Show Dependency/withdrawal Cannabis as a Substitute for Alcohol: A Harm-Reduction Approach Mikuriya TH 2004 Cannabis;Nabilone Uncontrolled case report Cannabis is a successful substituent of alcohol
Show Spasticity;Spinal cord injury;Multiple sclerosis;Pain A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Wade DT, Robson P, House H, Makela P, Aram J. 2003 Cannabis;Delta-9-THC;Cannabidiol Controlled study Pain relief associated with both THC and CBD was significantly superior to placebo. Impaired bladder control, muscle spasms and spasticity were improved by cannabis in some patients
Show Appetite loss/weight loss;Alzheimer’s disease Safety and efficacy of dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia: A retrospective chart review Patel S, Shua-Haim JR, Pass M 2003 Delta-9-THC Open study Weight gain in all, reduction of agitation in 65%.
Show HIV/AIDS Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M 2003 Cannabis;Delta-9-THC Controlled study Cannabis and THC had no significant effect on HI virus load and on CD4+ and CD8+ cell count
Show Spasticity;Spinal cord injury The treatment of spasticity with D9-tetrahydrocannabinol (D9-THC) in patients with spinal cord injury Hagenbach U, Luz S, Brenneisen R, Mäder M 2003 Delta-9-THC Controlled study Significant reduction of spasticity
Show Spasticity;Dystonia;Epilepsy;Anxiety Experiences with THC-treatment in children and adolescents Lorenz R 2003 Delta-9-THC Uncontrolled case report Positive effects of THC in children with severe neurological disorders
Show Multiple sclerosis;Pain Randomised controlled trial of cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis. Young CA, Rog DJ 2003 Cannabis Controlled study Significant reduction in pain
Show Pain Efficacy of two cannabis-based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial Berman J, Lee J, Cooper M, Cannon A, Sach J, McKerral S, Taggart M, Symonds C, Fishel K, Birch R 2003 Cannabis;Delta-9-THC Controlled study Significant pain relief and improvement of sleep
Show Pain Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial. Karst M, Salim K, Burstein S, Conrad I, Hoy L, Schneider U. 2003 Other cannabinoids Controlled study Significant reduction of pain
Show Pain Cannabis use for chronic non-cancer pain: results of a prospective survey. Ware MA, Doyle CR, Woods R, Lynch ME, Clark AJ 2003 Cannabis Survey Cannabis use is prevalent among the chronic non-cancer pain population
Show Alzheimer’s disease Open-label study of dronabinol in the treatment of refractory agitation in Alzheimer’s disease: a pilot study Ross JS, Shua-Haim JR 2003 Delta-9-THC Open study Significant reduction of agitation
Show HIV/AIDS;Pain The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods. Abrams DI, Jay Ch, Petersen K, Shade S, Vizoso H, Reda H, Benowitz N, Rowbotham M. 2003 Cannabis Open study 10 of the 16 participants experienced a greater than 30% reduction in their pain
Show Tourette’s syndrome Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial. Muller-Vahl KR, Schneider U, Prevedel H, Theloe K, Kolbe H, Daldrup T, Emrich HM. 2003 Delta-9-THC Controlled study Results provide evidence that THC is effective in the treatment of tics.
Show Pain Lack of analgesic efficacy of oral delta-9-tetrahydrocannabinol in postoperative pain. Buggy DJ, Toogood L, Maric S, Sharpe P, Lambert DG, Rowbotham DJ 2003 Delta-9-THC Controlled study 5 mg was ineffective in reduding postoperative pain.
Show Spasticity;Multiple sclerosis;Pain Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial. Zajicek J, Fox P, Sanders H, Wright D, Vickery J, Nunn A, Thompson A, on behalf of the UK 2003 Cannabis;Delta-9-THC Controlled study No effect of cannabinoids on spasticity as measured by the Ashworth scale, while patient-reported spasticity and pain decreased.
Show Pain A case of cannabinoid rotation in a young woman with chronic cystitis Krenn H Daha LK Oczenski W Fitzgerald R D 2003 Delta-9-THC;Nabilone Uncontrolled case report THC reduced pain with low side effects; nabilone caused strong psychic side effects
Show Pain Cannabis reduces opioid dose in the treatment of chronic non-cancer pain. Lynch ME, Clark AJ. 2003 Cannabis Uncontrolled case report Improvement in pain, spasticity, bladder spasm, and sleep.
Show Spasticity;Multiple sclerosis;Pain;Depression Cannabis use as described by people with multiple sclerosis. Page SA, Verhoef MJ, Stebbins RA, Metz LM, Levy JC. 2003 Cannabis Survey Improvement of pain, spasticity and anxiety/depression
Show Pain The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions. Naef M, Curatolo M, Petersen-Felix S, Arendt-Nielsen L, Zbinden A, Brenneisen R. 2003 Delta-9-THC Controlled study No effect of THC on experimental pain in healthy subjects
Show Survey on the medical use of cannabis and THC in Germany. Grotenhermen F, Schnelle M. 2003 Cannabis;Delta-9-THC Survey Cannabis and THC were effective in many conditions
Show Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. Dvorak M, Watkinson A, McGlone F, Rukwied R. 2003 Other cannabinoids Controlled study Peripheral administration of HU210 attenuates histamine-induced itch
Show Pain Cannabinoid agonists attenuate capsaicin-induced responses in human skin. Rukwied R, Watkinson A, McGlone F, Dvorak M. 2003 Other cannabinoids Controlled study A topically applied cannabinoid receptor agonist (HU210) reduced pain caused by capsaicin
Show Appetite loss/weight loss;Cancer Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: a North Central Cancer Treatment Group study. Jatoi A, Windschitl HE, Loprinzi CL, Sloan JA, Dakhil SR, Mailliard JA, Pundaleeka S, Kardinal CG, Fitch TR, Krook JE, Novotny PJ, Christensen B. 2002 Delta-9-THC Controlled study megestrol acetate was superior to THC
Show Pain [The therapeutic use of delta-9-tetrahydrocannabinol (dronabinol) in refractory neuropathic pain] [Article in French]. Clermont-Gnamien S, Atlani S, Attal N, Le Mercier F, Guirimand F, Brasseur L. 2002 Delta-9-THC Open study No signficant effect of THC on pain
Show Tourette’s syndrome Treatment of Tourette’s syndrome with Delta 9-tetrahydrocannabinol (THC): a randomized crossover trial. Muller-Vahl KR, Schneider U, Koblenz A, Jobges M, Kolbe H, Daldrup T, Emrich HM. 2002 Delta-9-THC Controlled study Significant improvement of tics and obsessive-compulsive behavior after treatment with THC.
Show Dystonia Randomised, double-blind, placebo-controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia. Fox SH, Kellett M, Moore AP, Crossman AR, Brotchie JM 2002 Nabilone Controlled study No significant reduction in dystonia following treatment with nabilone
Show Spasticity;Multiple sclerosis Safety, tolerability, and efficacy of orally administered cannabinoids in MS. Killestein J, Hoogervorst EL, Reif M, Kalkers NF, Van Loenen AC, Staats PG, Gorter RW, Uitdehaag BM, Polman CH 2002 Cannabis;Delta-9-THC Controlled study Compared with placebo, neither THC nor plant-extract treatment reduced spasticity.
Show Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. Neff GW, O’Brien CB, Reddy KR, Bergasa NV, Regev A, Molina E, Amaro R, Rodriguez MJ, Chase V, Jeffers L, Schiff E. 2002 Delta-9-THC Open study THC signficantly reduced intractable cholestatic related pruritus
Show Spasticity A casuistic rationale for the treatment of spastic and myocloni in a childhood neurodegenerative disease: neuronal ceroid lipofuscinosis of the type Jansky-Bielschowsky. Lorenz R. 2002 Delta-9-THC Uncontrolled case report Improvement of spasticity
Show Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis E. Russo, M.L. Mathre, A. Byrne, R. Velin, P.J. Bach, J. Sanchez-Ramos, K.A. Kirlin 2002 Cannabis Uncontrolled case report Effective treatment of different serious conditions with cannabis
Show Dependency/withdrawal Crack heads and roots daughters: The therapeutic use of cannabis in Jamaica. Dreher M. 2002 Cannabis Open study Cannabis was the most effective and readily available therapy to quit cocaine use
Show Nausea/vomiting Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat? Curry W-NL 2002 Cannabis Uncontrolled case report Cannabis effective in treating nausea and vomiting in pregnant women
Show Cannabis treatments in obstetrics and gynecology: A historical review. Russo E. 2002 Cannabis Uncontrolled case report Cannabis was effective in a wide range of gynecological conditions
Show Tourette’s syndrome Müller-Vahl KR, Schneider U, Emrich HM. Combined treatment of Tourette syndrome with delta-9-THC and dopamine receptor agonists. 2002 Delta-9-THC Uncontrolled case report THC may be combined with neuroleptics
Show Parkinson’s disease Cannabinoids reduce levodopa-induced dyskinesia in Parkinson’s disease: a pilot study. Sieradzan KA, Fox SH, Hill M, Dick JP, Crossman AR, Brotchie JM 2001 Nabilone Controlled study significant reduction of levodopa-induced dyskinesia
Show Nausea/vomiting Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. Soderpalm AH, Schuster A, de Wit H 2001 Cannabis Controlled study Ondansetron superior to cannabis in reducing nausea and vomiting
Show Spinal cord injury Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients. Hagenbach U, Ghafoor N, Brenneisen R, Luz S, Mäder M. 2001 Delta-9-THC Controlled study Significant improvement of some parameters of bladder function
Show Multiple sclerosis Acute and chronic effects of cannabis based medicinal extract on refractory lower urinary tract dysfunction in patients with advanced multiple sclerosis – early results Brady CM, DasGupta R, Wiseman OJ, Berkley KJ, Fowler CJ 2001 Cannabis Open study Mean maximum cystometric capacity increased
Show Pain [Tetrahydrocannabinol for treatment of chronic pain] [Article in German] Elsner F, Radbruch L, Sabatowski R. 2001 Delta-9-THC Uncontrolled case report Sufficient pain relief in three patients
Show Nausea/vomiting;Cancer;Cancer chemotherapy Effects of smoked cannabis and oral delta-9-tetrahydrocannabinol on nausea and emesis after cancer chemotherapy: A review of state clinical trials. Musty RE, Rossi R. 2001 Cannabis;Delta-9-THC Open study Cannabis caused symptom relief in 70-100%, dronabinol caused symptom relief in 76-88%
Show Appetite loss/weight loss;Spasticity;Pain Marijuana in the management of amyotrophic lateral sclerosis. Carter GT, Rosen BS. 2001 Cannabis Uncontrolled case report Cannabis relieved several symptoms of ALS
Show HIV/AIDS Differential Effects of Medical Marijuana Based on Strain and Route of Administration: A Three-Year Observational Study Corral VL 2001 Cannabis Uncontrolled case report
Show Hemp for headache: An in-depth historical and scientific review of cannabis in migraine treatment. Russo EB 2001 Cannabis Uncontrolled case report Cannabis may be effective in the treatment of headache
Show Nausea/vomiting;Appetite loss/weight loss;HIV/AIDS Marijuana Use in HIV-Positive and AIDS Patients: Results of an Anonymous Mail Survey Sidney S. 2001 Cannabis Survey 22.4 % used cannabis for medicinal purposes
Show Pain Antinociceptive, subjective and behavioral effects of smoked marijuana in humans. Greenwald MK, Stitzer ML. 2000 Cannabis Controlled study Cannabis produced dose-dependent antinociception
Show Multiple sclerosis Randomised controlled trial of cannabis based medicine (CBM, Stativex®) to treat detrusor overactivity in multiple sclerosis. Kavia R, De Ridder D, Sarantis N, Constantinescu C, Fowler. 2000 Cannabis Controlled study There was no effect on daily incontinence, but the cannabis extract was superior to placebo for nocturia.
Show Tourette’s syndrome Treatment of Tourette’s syndrome with delta-9-tetrahydrocannabinol. Muller-Vahl KR, Schneider U, Kolbe H, Emrich HM. 1999 Delta-9-THC Uncontrolled case report Improvement of tics and obsessive-compulsive behavior
Show Multiple sclerosis;Pain Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors. Hamann W, di Vadi PP. 1999 Nabilone Open study Relieve of pain
Show Dependency/withdrawal Therapeutic use of cannabis by crack addicts in Brazil. Labigalini E Jr, Rodrigues LR, Da Silveira DX. 1999 Cannabis Open study Cannabis use helped patients to quit crack use by reducing the craving symptoms
Show Dependency/withdrawal Therapeutic use of cannabis by crack addicts in Brazil. Labigalini E, Jr., Rodrigues LR, Da Silveira DX. 1999 Cannabis Open study Cannabis reduced craving and helped patients to quit cocaine
Show Bipolar disorders The use of cannabis as a mood stabilizer in bipolar disorder: anecdotal evidence and the need for clinical research. Grinspoon L, Bakalar JB. 1998 Cannabis Uncontrolled case report A number of patients find cannabis (marihuana) useful in the treatment of their bipolar disorder
Show Tourette’s syndrome Cannabinoids: possible role in patho-physiology and therapy of Gilles de la Tourette syndrome. Muller-Vahl KR, Kolbe H, Schneider U, Emrich HM. 1998 Cannabis Survey Evidence that marijuana improves tics and behavioural disorders in TS.
Show Parkinson’s disease The effects of the cannabinoid receptor agonist nabilone on L-DOPA induced dyskinesia in patients with idiopathic Parkinson’s disease (PD). Sieradzan KA, Fox SH, Dick J, Brotchie JM. 1998 Nabilone Controlled study Activation of cannabinoid receptors can reduce L-DOPA-induced dyskinesia in man without aggravating parkinsonism.
Show Hiccups Marijuana for intractable hiccups. Gilson I, Busalacchi M. 1998 Cannabis Uncontrolled case report Smoking cannabis stopped hiccups that did not respond to usual medications on the 8th day
Show Spasticity;Multiple sclerosis;Pain;Tremor;Depression The perceived effects of smoked cannabis on patients with multiple sclerosis. Consroe P, Musty R, Rein J, Tillery W, Pertwee R 1997 Cannabis Survey In more than 80% improvement of spasticity, pain, tremor, depression, anxiety, and paresthesia
Show Pain Pain relief with oral cannabinoids in familial Mediterranean fever. Holdcroft A, Smith M, Jacklin A, Hodgson H, Smith B, Newton M, Evans F 1997 Cannabis Controlled study reduction of need for morphin
Show Nausea/vomiting;Cancer;Cancer chemotherapy Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol). Gonzalez-Rosales F, Walsh D 1997 Delta-9-THC Uncontrolled case report patients was treated with several antiemetic drugs, but it was not until dronabinol was added that the nausea and vomiting stopped
Show Appetite loss/weight loss;HIV/AIDS Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia. Beal JE, Olson R, Lefkowitz L, Laubenstein L, Bellman P, Yangco B, Morales JO, Murphy R, Powderly W, Plasse TF, Mosdell KW, Shepard KV 1997 Delta-9-THC Open study tendency to stable weight for 7 months
Show Appetite loss/weight loss;HIV/AIDS The safety and pharmacokinetics of single-agent and combination therapy with megestrol acetate and dronabinol for the treatment of HIV wasting syndrome. The DATRI 004 Study Group. Division of AIDS Treatment Research Initiative. Timpone JG, Wright DJ, Li N, Egorin MJ, Enama ME, Mayers J, Galetto G 1997 Delta-9-THC Controlled study weight loss with THC, weight gain with megestrol acetate
Show Appetite loss/weight loss;Alzheimer’s disease Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer’s disease. Volicer L, Stelly M, Morris J, McLaughlin J, Volicer BJ 1997 Delta-9-THC Controlled study higher weight gain with THC; reduction of disturbed behaviour with THC
Show Nausea/vomiting;Cancer chemotherapy Marijuana to prevent nausea and vomiting in cancer patients: a survey of clinical oncologists. Schwartz RH, Voth EA, Sheridan MJ. 1997 Cannabis Survey Only a small percentage of oncologists prescribed marijuana
Show Multiple sclerosis; Spinal cord injury; Spasticity; Pain The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. Brenneisen R, Egli A, Elsohly MA, Henn V, Spiess Y 1996 Delta-9-THC improvement of joint function and ability to walk; in 1 patient additional alleviation of pain
Show Cancer chemotherapy; Nausea/vomiting An efficient new cannabinoid antiemetic in pediatric oncology. Abrahamov A, Abrahamov A, Mechoulam R 1995 Delta-9-THC Open study complete prevention of emesis
Show Multiple sclerosis; Spasticity Nabilone in the treatment of multiple sclerosis. Martyn CN, Illis LS, Thom J 1995 Nabilone Controlled study improvement of muscle spasms and frequency of nocturia
Show Appetite loss/weight loss;HIV/AIDS;Depression Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. Beal JE, Olson R, Laubenstein L, Morales JO, Bellman P, Yangco B, Lefkowitz L, Plasse TF, Shepard KV 1995 Delta-9-THC Controlled study increased appetite; improvement in mood; stabel weight
Show Spasticity;Spinal cord injury Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivative. Kogel RW, Johnson PB, Chintam R, Robinson CJ, Nemchausky BA. 1995 Delta-9-THC Open study Spasticity was markedly improved in 2 o 5 patients
Show Appetite loss/weight loss;Cancer A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia. Nelson K, Walsh D, Deeter P, Sheehan F 1994 Delta-9-THC Open study increase of appetite in 13 patients
Show Multiple sclerosis Short-term effects of smoking marijuana on balance in patients with multiple sclerosis and normal volunteers Greenberg HS, Werness SAS, Pugh JE, Andrus RO, Anderson DJ, Domino EF 1994 Cannabis Controlled study Cannabis reduced posture and balance in patients with MS
Show Nausea/vomiting Effect of nabilone on nausea and vomiting after total abdominal hysterectomy. Lewis IH, Campbell DN, Barrowcliffe MP. 1994 Nabilone Controlled study Nabilone and metoclopramide were equally effective in reducing nausea and vomiting
Show Appetite loss/weight loss;HIV/AIDS Effect of dronabinol on nutritional status in HIV infection. Struwe M, Kaempfer SH, Geiger CJ, Pavia AT, Plasse TF, Shepard KV, Ries K, Evans TG. 1993 Delta-9-THC Controlled study Trends toward weight gain, improved appetite, decreased symptom stress
Show Tourette’s syndrome Effective treatment of Tourette’s syndrome with marijuana. Hemming M, Yellowlees PM. 1993 Cannabis Uncontrolled case report Improvement of symptoms with cannabis
Show HIV/AIDS; Appetite loss/weight loss; Depression Dronabinol stimulates appetite and causes weight gain in HIV patients. Plasse T, Conant M, Gorter R, Shepard KV 1992 Delta-9-THC Controlled study increase in appetite, trend toward weight gain
Show Appetite loss/weight loss;HIV/AIDS Dronabinol effects on weight in patients with HIV infection. Gorter R, Seefried M, Volberding P 1992 Delta-9-THC Open study weight gain
Show Nausea/vomiting;Cancer;Cancer chemotherapy Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting. Lane M, Vogel CL, Ferguson J, Krasnow S, Saiers JL, Hamm J 1991 Delta-9-THC Controlled study prochlorperazine better than THC, both drugs combined better than both alone
Show Appetite loss/weight loss;HIV/AIDS Recent clinical experience with dronabinol. Plasse TF, Gorter RW, Krasnow SH, Lane M, Shepard KV, Wadleigh RG 1991 Delta-9-THC Open study Significant weight gain
Show Controlled clincal trial of cannabidiol in Huntington’s disease. Consroe P, Laguna J, Allender J, Snider S, Stern L, Sandyk R, Kennedy K, Schram K 1991 Cannabidiol Controlled study CBD was neither symptomatically effective nor toxic.
Show Nausea/vomiting;Cancer chemotherapy Marijuana as antiemetic medicine: a survey of oncologists’ experiences and attitudes. Doblin RE, Kleiman MA. 1991 Cannabis Survey 54% of oncologists thought marijuana should be available on prescription
Show Spasticity;Spinal cord injury;Pain Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. Maurer M, Henn V, Dittrich A, Hofmann A 1990 Delta-9-THC Controlled study THC and codeine reduced pain; THC reduced spasticity
Show Appetite loss/weight loss;Cancer Dronabinol enhancement of appetite in cancer patients. Wadleigh R, Spaulding GM, Lumbersky B, Zimmer M, Shepard K, Plasse T 1990 Delta-9-THC Open study Patients continued to loose, but the weight loss decreased in all groups; appetite and mood increased
Show Parkinson’s disease Marijuana for parkinsonian tremor. Frankel JP, Hughes A, Lees AJ, Stern GM. 1990 Cannabis Open study No improvement of tremor
Show Appetite loss/weight loss;Cancer Dronabinol enhancement of appetite in cancer patients. Wadleigh R, Spaulding GM, Lumbersky B, Zimmer M, Shepard K, Plasse T. 1990 Delta-9-THC Open study Dronabinol stimulated mood and appetite
Show Multiple sclerosis; Spasticity; Ataxia Effect of cannabinoids on spasticity and ataxia in multiple sclerosis. Meinck HM, Schönle PW, Conrad B 1989 Cannabis Controlled study improvement of tremor, spasticity and ataxia
Show Nausea/vomiting;HIV/AIDS Nabilone as effective therapy for intractable nausea and vomiting in AIDS. Green ST, Nathwani D, Goldberg DJ, Kennedy DH. 1989 Nabilone Uncontrolled case report Intractable nausea and vomiting was effectively relieved with nabilone
Show Nausea/vomiting;Cancer;Cancer chemotherapy Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy McCabe M, Smith FP, Goldberg D, Macdonald J, Woolley PV, Warren R 1988 Delta-9-THC Controlled study THC decreased nausea and vomiting in 23 of 36 (64%) patients
Show Appetite loss/weight loss Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. Foltin RW, Fischman MW, Byrne MF. 1988 Cannabis Controlled study Increases in body weight during periods of active marijuana smoking were greater than predicted by caloric intake alone.
Show Nausea/vomiting;Cancer;Cancer chemotherapy A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues. Cunningham D, Bradley CJ, Forrest GJ, Hutcheon AW, Adams L, Sneddon M, Harding M, Kerr DJ, Soukop M, Kaye SB. 1988 Nabilone Open study Metoclopramide/dexamethasone superior to nabilone/prochlorperazine
Show Nausea/vomiting;Cancer;Cancer chemotherapy Inhalation marijuana as an antiemetic for cancer chemotherapy. Vinciguerra V, Moore T, Brennan E. 1988 Cannabis Open study Marijuana effective as antiemetic agent
Show Tourette’s syndrome Marijuana and Tourette’s syndrome. Sandyk R, Awerbuch G. 1988 Cannabis Uncontrolled case report The patients notes a significant amelioration of symptoms when smoking cannabis
Show Multiple sclerosis; Spasticity Delta-9-THC in the treatment of spasticity associated with multiple sclerosis. Ungerleider JT, Andyrsiak T, Fairbanks L, Ellison GW, Myers LW 1987 Delta-9-THC Controlled study significant subjective improvement in spasticity at doses of 7.5 mg and above; no objective improvement
Show Nausea/vomiting;Cancer;Cancer chemotherapy Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. Chan HS, Correia JA, MacLeod SM 1987 Nabilone Controlled study Nabilone effective as antiemetic drug for children
Show Nausea/vomiting A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. Priestman SG, Priestman TJ, Canney PA. 1987 Nabilone Controlled study Nabilone similar effective as metoclopramide
Show Pain Lack of effect of cannabidiol in sustained neuropathia. Lindstrom P, Lindblom U, Boreus L. 1987 Cannabidiol Controlled study no effect of CBD on pain
Show Dystonia; Parkinson’s disease Open label evaluation of cannabidiol in dystonic movement disorders. Consroe P, Sandyk R, Snider SR 1986 Cannabidiol Open study 20-50% improvement of dystonia; deterioration of tremor and hypokinesia in 2 patients with Parkinson’s disease
Show Epilepsy Anticonvulsant effect of cannabidiol. Ames FR, Cridland S 1986 Cannabidiol Controlled study no significant effect in addition to standard medication
Show Spasticity Effect of Delta-9-THC on EMG Measurements in Human Spasticity Truong XT, Hanigan WC 1986 Delta-9-THC Controlled study THC reduced several types of spastic manifestations
Show Appetite loss/weight loss Behavioral analysis of marijuana effects on food intake in humans. Foltin RW, Fishman MW, Brady JV. 1986 Cannabis Controlled study The administration of two or three active marijuana cigarettes during the social access period increased average daily caloric intake.
Show Nausea/vomiting;Cancer;Cancer chemotherapy Nabilone and metoclopramide in the treatment of nausea and vomiting due to cisplatinum: a double blind study. Crawford SM, Buckman R. 1986 Nabilone Controlled study No difference between nabilone and metoclopramide
Show Nausea/vomiting;Cancer;Cancer chemotherapy Nabilone: an alternative antiemetic for cancer chemotherapy. Dalzell AM, Bartlett H, Lilleyman JS. 1986 Nabilone Controlled study Even for young children nabilone is an effective antiemetic, superior to domperidone.
Show Nausea/vomiting;Cancer;Cancer chemotherapy Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy. Niederle N, Schutte J, Schmidt CG. 1986 Nabilone Controlled study Nabilone superior to alizapride.
Show Nausea/vomiting;Cancer;Cancer chemotherapy Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. Pomeroy M, Fennelly JJ, Towers M. 1986 Nabilone Controlled study Nabilone superior to domperidone
Show Dystonia Cannabidiol in dystonic movement disorders. Sandyk R, Snider SR, Consroe P, Elias SM. 1986 Cannabidiol Uncontrolled case report Cannabidiol (CBD) reduced dystonic movements
Show Spasticity The effect of delta-9-THC on human spasticity. Hanigan WC, Destree R, Truong XT. 1986 Delta-9-THC Controlled study Delta-9-THC proved clinically beneficial in two of five patients with intractable spasticity.
Show Nausea/vomiting;Cancer;Cancer chemotherapy THC or Compazine for the cancer chemotherapy patient–the UCLA study. Part II: Patient drug preference. Ungerleider JT, Sarna G, Fairbanks LA, Goodnight J, Andrysiak T, Jamison K. 1985 Delta-9-THC Controlled study nausea reduction was the main determinant of preference between THC and prochlorperazine
Show Nausea/vomiting;Cancer;Cancer chemotherapy A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. Niiranen A, Mattson K. 1985 Nabilone Controlled study Nabilone is a moderately effective anti-emetic drug
Show Parkinson’s disease Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia. Snider SR, Consroe P. 1985 Cannabidiol Uncontrolled case report Improvement of dyskinesia
Show Cancer;Cancer chemotherapy Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting. Citron ML, Herman TS, Vreeland F, Krasnow SH, Fossieck BE Jr, Harwood S, Franklin R, Cohen MH. 1985 Delta-9-THC;Other cannabinoids Controlled study Levonantradol appears to be at least as effective an antiemetic as THC ; well-tolerated side-effects.
Show Nausea/vomiting;Cancer;Cancer chemotherapy Antiemetic therapy: a review of recent studies and a report of a random assignment trial comparing metoclopramide with delta-9-tetrahydrocannabinol. Gralla RJ, Tyson LB, Bordin LA, Clark RA, Kelsen DP, Kris MG, Kalman LB, Groshen S 1984 Delta-9-THC Controlled study Poorer antiemetic control and more side effects with dronabinol than with the metoclopramide, both better than placebo
Show Nausea/vomiting;Cancer;Cancer chemotherapy Randomized double blind comparison of delta-9-tetrahydroicannabinol (THC) and marijuana as chemotherapy antiemetics. Levitt M, Faiman C, Hawks R, Wilson A 1984 Cannabis;Delta-9-THC Controlled study 9 patients no preference; 7 preferred oral THC, 4 preferred marijuana cigarettes (double-blind, double dummy crossover study)
Show Asthma Acute and subacute bronchial effects of oral cannabinoids. Gong H Jr, Tashkin DP, Simmons MS, Calvarese B, Shapiro BJ 1984 Delta-9-THC Open study acute bronchodilator activity of delta 9-THC; no effect of cannabidiol; daily use of delta 9-THC not associated with tolerance
Show Dystonia Treatment of Meige’s syndrome with cannabidiol. Snider S.R, Consroe P. 1984 Cannabidiol Uncontrolled case report 50% improvement in spasm severity and frequency
Show Cancer chemotherapy Dose ranging evaluation of the antiemetic efficacy and toxicity of intramuscular levonantradol in cancer subjects with chemotherapy-induced emesis. Stambaugh JE Jr, McAdams J, Vreeland F. 1984 Other cannabinoids Controlled study Levonantradol more effective than placebo
Show Nausea/vomiting;Cancer An initial evaluation of Nabilone in the control of radiotherapy-induced nausea and vomiting. Priestman TJ, Priestman SG. 1984 Nabilone Open study Patients who did not respond to metaclopramide responded to nabilone.
Show Nausea/vomiting;Cancer Tetrahydrocannabinol vs. prochlorperazine. The effects of two antiemetics on patients undergoing radiotherapy. Ungerleider JT, Andrysiak TA, Fairbanks LA, Tesler AS, Parker RG. 1984 Delta-9-THC Controlled study THC was slightly superior to prochlorperazine
Show Multiple sclerosis; Tremor Tetrahydrocannabinol for tremor in multiple sclerosis. Clifford DB 1983 Delta-9-THC Controlled study 2 patients with objective improvement, 5 with subjective improvement
Show Asthma Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects. Gong H Jr, Tashkin DP, Calvarese B 1983 Nabilone Controlled study moderate bronchodilator action in healthy subjects; no difference to placebo in asthmatics
Show Appetite loss/weight loss A double-blind trial of delta 9-tetrahydrocannabinol in primary anorexia nervosa. Gross H, Ebert MH, Faden VB, Goldberg SC, Kaye WH, Caine ED, Hawks R, Zinberg N 1983 Delta-9-THC Controlled study no significant difference between THC and diazepam
Show Nausea/vomiting;Cancer;Cancer chemotherapy Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. Ahmedzai S, Carlyle DL, Calder IT, Moran F. 1983 Nabilone Controlled study Symptom scores were significantly better for patients on nabilone for nausea, retching and vomiting.
Show Nausea/vomiting;Cancer;Cancer chemotherapy [Randomized comparative trial of a new anti-emetic: nabilone, in cancer patients treated with cisplatin][Article in French] George M, Pejovic MH, Thuaire M, Kramar A, Wolff JP. 1983 Nabilone Controlled study Nabilone, in comparison with chlorpromazine did not significantly reduce the number of vomiting, but most patients preferred nabilone.
Show Nausea/vomiting;Cancer;Cancer chemotherapy A randomised multicentre single blind comparison of a cannabinoid anti-emetic (levonantradol) with chlorpromazine in patients receiving their first cytotoxic chemotherapy. Hutcheon AW, Palmer JB, Soukop M, Cunningham D, McArdle C, Welsh J, Stuart F, Sangster G, Kaye S, Charlton D, et al. 1983 Other cannabinoids Controlled study 0.5 mg levonantradol was a more effective antiemtic than 25 mg chlorpromazine
Show Nausea/vomiting;Cancer chemotherapy Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine. Ungerleider JT, Andrysiak T, Fairbanks L, Goodnight J, Sarna G, Jamison K. 1982 Delta-9-THC Controlled study No significant differences between THC and prochlorperazine
Show Spasticity;Spinal cord injury Cannabis effect on spasticity in spinal cord injury. Malec J, Harvey RF, Cayner JJ. 1982 Cannabis Survey Decreased spasticity with marijuana use
Show Nausea/vomiting Randomised clinical trial of levonantradol and chlorpromazine in the prevention of radiotherapy-induced vomiting. Lucraft HH, Palmer MK 1982 Other cannabinoids Controlled study The frequency of vomiting was similar after levonantradol and chlorpromazine.
Show Cancer;Cancer chemotherapy A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy. Johansson R, Kilkku P, Groenroos M. 1982 Nabilone Controlled study Severity of nausea and number of vomiting ejections and dry retching episodes were significantly less under nabilone.
Show Nausea/vomiting;Cancer;Cancer chemotherapy A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting. Jones SE, Durant JR, Greco FA, Robertone A. 1982 Nabilone Controlled study Nabilone is an effective antiemetic agent for chemotherapy-induced nausea and vomiting.
Show Spasticity Treatment of human spasticity with delta 9-tetrahydrocannabinol. Petro DJ, Ellenberger C Jr 1981 Delta-9-THC Controlled study reduced spasticity with 10 mg THC
Show Nausea/vomiting;Cancer;Cancer chemotherapy A prospective evaluation of delta-9-tetrahydrocannabinol as an antiemetic in patients receiving adriamycin and cytoxan chemotherapy. Chang AE, Shiling DJ, Stillman RC, Goldberg NH, Seipp CA, Barofsky I, Rosenberg 1981 Delta-9-THC Controlled study no significant reduction of the number of vomiting, volume of emesis, degree of nausea, or duration of nausea
Show Nausea/vomiting;Cancer;Cancer chemotherapy Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics. Levitt M, Wilson A, Bowman D, Faiman C, Kemel S, Krepart G 1981 Delta-9-THC Controlled study THC 15 mg was the most effective against vomiting, prochlorperazine was the most effective antinauseant
Show Pain Evaluation of intramuscular levonantradol and placebo in acute postoperative pain. Jain AK, Ryan JR, McMahon FG, Smith G. 1981 Other cannabinoids Controlled study significant pain relief compared with placebo
Show Glaucoma Topical delta 9-tetrahydrocannabinol and aqueous dynamics in glaucoma. Merritt JC, Perry DD, Russell DN, Jones BF 1981 Delta-9-THC Controlled study no effect
Show Nausea/vomiting;Cancer;Cancer chemotherapy Comparative trial of the antiemetic effects of THC and haloperidol Neidhart JA, Gagen MM, Wilson HE, Young DC 1981 Delta-9-THC Controlled study THC and haloperidol equally effective
Show Cancer chemotherapy;Glaucoma Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications. Levitt M, Wilson A, Bowman D, Kemel S, Krepart G, Marks V, Schipper H, Thomson G, Weinerman B, Weinerman R 1981 Delta-9-THC Controlled study Patients were remarkably free of adverse physiologic effects.
Show Nausea/vomiting;Cancer;Cancer chemotherapy Nabilone: an effective antiemetic in patients receiving cancer chemotherapy. Einhorn LH, Nagy C, Furnas B, Williams SD. 1981 Nabilone Controlled study Sixty patients (75 per cent) reported nabilone to be more effective than prochlorperazine for relief of nausea and vomiting.
Show Pain A study of levonantradol, a cannabinol derivative, for analgesia in post operative pain. Kantor TG, Hopper M. 1981 Other cannabinoids Controlled study Levonantradol has analgetic activity but may have central nervous system adverse effects in humans.
Show Glaucoma Clinical relevance of cannabis tolerance and dependence. Jones RT, Benowitz NL, Herning RI. 1981 Delta-9-THC Controlled study
Show Anxiety The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety. Fabre LF, McLendon D. 1981 Nabilone Controlled study Dramatic improvement in anxiety
Show Anxiety Single-dose study of nabilone in anxious volunteers. Glass RM, Uhlenhuth EH, Hartel FW, Schuster CR, Fischman MW. 1981 Nabilone Controlled study Antianxiety effects in 2 of the 8 subjects
Show Pain Effects of moderate and high doses of marihuana on thermal pain: a sensory decision theory analysis. Clark WC, Janal MN, Zeidenberg P, Nahas GG. 1981 Cannabis Controlled study Cannabis increased perseption of pain
Show Cancer chemotherapy; Nausea/vomiting Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. Sallan SE, Cronin C, Zelen M, Zinberg NE 1980 Delta-9-THC Controlled study no nausea and vomiting in 36 of 79 courses of chemotherapy with THC compared to 16 of 78 courses in patients who received prochlorperazine; improved appetite with THC
Show Cancer chemotherapy; Nausea/vomiting Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis. Orr LE, McKernan JF, Bloome B 1980 Delta-9-THC Controlled study no nausea and no vomiting (complete response) in 73% (40/55 courses) in THC group
Show Nausea/vomiting;Cancer;Cancer chemotherapy The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy. Colls BM, Ferry DG, Gray AJ, Harvey VJ, McQueen EG. 1980 Delta-9-THC Controlled study tetrahydrocannabinol given by mouth has an antiemetic effect of approximately the same order as thiethylperazine and metoclopramide
Show Epilepsy Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Cunha JM, Carlini EA, Pereira AE, Ramos OL, Pimentel C, Gagliardi R, Sanvito WL, Lander N, Mechoulam R 1980 Cannabidiol Controlled study 4 of the 8 CBD subjects remained almost free of convulsive crises and 3 other patients demonstrated partial improvement
Show Spasticity;Pain Marihuana as a therapeutic agent for muscle spasm or spasticity. Petro DJ 1980 Cannabis Uncontrolled case report Relief from spasticity and pain
Show Glaucoma Effect of marihuana on intraocular and blood pressure in glaucoma. Merritt JC, Crawford WJ, Alexander PC, Anduze AL, Gelbart SS 1980 Cannabis Controlled study Marihuana inhalation decreased intraocular and blood pressure.
Show Cancer;Cancer chemotherapy Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis. Steele N, Gralla RJ, Braun DW Jr, Young CW. 1980 Nabilone Controlled study Both nabilone and prochlorperazine produced antiemetic effects
Show Epilepsy Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Cunha JM, Carlini EA, Pereira AE, Ramos OL, Pimentel C, Gagliardi R, Sanvito WL, Lander N, Mechoulam R 1980 Cannabidiol Controlled study 4 of the 8 CBD subjects remained almost free of convulsive crises and 3 other patients demonstrated partial improvement
Show Nausea/vomiting;Cancer;Cancer chemotherapy Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. Frytak S, Moertel CG, O’Fallon JR, Rubin J, Creagan ET, O’Connell MJ, Schutt AJ, Schwartau NW 1979 Delta-9-THC Controlled study THC and PCP equally effective; both better than placebo; THC produced psychic effects in 82%
Show Nausea/vomiting;Cancer;Cancer chemotherapy Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation. Chang AE, Shiling DJ, Stillman RC, Goldberg NH, Seipp CA, Barofsky I, Simon RM, Rosenberg SA. 1979 Delta-9-THC Controlled study 14 of 15 patients had decreased vomiting and nausea
Show Nausea/vomiting;Cancer;Cancer chemotherapy Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo Kluin-Nelemans JC, Nelemans FA, Meuwissen OJATh, Maes RAA 1979 Delta-9-THC Controlled study dronabinol superior to placebo (P<.01 for difference between groups at days 1 and 8 independently)
Show Glaucoma Effects of tetrahydrocannabinol on arterial and intraocular hypertension. Crawford WJ, Merritt JC 1979 Cannabis Controlled study drop in IOP parallel with drop in arterial blood pressure
Show Nausea/vomiting Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol. Ekert H, Waters KD, Jurk IH, Mobilia J, Loughnan P 1979 Delta-9-THC Controlled study THC was effective in reducing nausea and vomiting but not in all patients
Show Nausea/vomiting;Cancer;Cancer chemotherapy Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. Herman TS, Einhorn LH, Jones SE, Nagy C, Chester AB, Dean JC, Furnas B, Williams SD, Leigh SA, Dorr RT, Moon TE. 1979 Nabilone Controlled study When both drugs were compared, both nausea and vomiting episodes were significantly lower in patients given nabilone.
Show Pain Effect of benzopyranoperidine, a delta-9-THC congener, on pain. Jochimsen PR, Lawton RL, VerSteeg K, Noyes Jr R 1978 Other cannabinoids Controlled study Bezopyranoperidine was not more effective than placebo
Show Cancer;Pain Effect of a nitrogen analog of tetrahydrocannabinol on cancer pain. Staquet M, Gantt C, Machin D. 1978 Other cannabinoids Controlled study NIB was superior to placebo and to secobarbital but is not useful clinically because of the frequency of side effects.
Show Glaucoma Effect of delta-9-tetrahydrocannabinol on intraocular pressure in humans. Cooler P, Gregg JM 1977 Delta-9-THC Controlled study reduction in intraocular pressure
Show Pain Effects of intravenous tetrahydrocannabinol on experimental and surgical pain. Psychological correlates of the analgesic response. Raft D, Gregg J, Ghia J, Harris L 1977 Delta-9-THC Controlled study No pain relief with THC
Show Asthma Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects. Tashkin DP, Reiss S, Shapiro BJ, Calvarese B, Olsen JL, Lodge JW. 1977 Delta-9-THC Controlled study THC effective in healthy subjects and 3 asthmatic subjects; aerosol caused bronchoconstriction in 2 asthmatic subjects
Show Cancer; Appetite loss/weight loss; Depression Regelson W, Butler JR, Schulz J, Kirk T, Peek L, Green ML, Zalis MO 1976 Delta-9-THC Controlled study weight gain with THC; weight los with placebo
Show Asthma Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients. Williams SJ, Hartley JP, Graham JD 1976 Delta-9-THC Controlled study significant broncholdilation with THC; faster action of salbutamol but both drugs equivalent at 1 hour
Show Cancer chemotherapy; Nausea/vomiting Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy. Sallan SE, Zinberg NE, Frei E 3d 1975 Delta-9-THC Controlled study for patients completing the study there were 5 complete responses (no vomiting) and 7 partial responses (50% decrease of vomiting) of overall 15 courses
Show Cancer; Pain Analgesic effect of delta-9-tetrahydrocannabinol. Noyes R Jr, Brunk SF, Baram DA, Canter A 1975 Delta-9-THC Controlled study pain relief with 15-20 mg THC
Show Cancer; Pain The analgesic properties of delta-9-tetrahydrocannabinol and codeine. Noyes R Jr, Brunk SF, Avery DAH, Canter AC 1975 Delta-9-THC Controlled study milde analgesic effect; with 20 mg THC strong adverse effects
Show Epilepsy Anticonvulsant nature of marihuana smoking. Consroe PF, Wood GC, Buchsbaum H 1975 Cannabis Uncontrolled case report Cannabis was able to control seizures in conjunction with phenobarbital and diphenylhydantoin.
Show Asthma Effects of smoked marijuana in experimentally induced asthma. Tashkin DP, Shapiro BJ, Lee YE, Harper CE 1975 Cannabis Controlled study after experimental induction of acute bronchospasm prompt correction of the bronchospasm with cannabis
Show Glaucoma Marijuana smoking and reduced pressure in human eyes: drug action or epiphenomenon? Flom MC, Adams AJ, Jones RT 1975 Delta-9-THC Open study IOP reduction in 7 of 15
Show Asthma Acute effects of smoked marijuana and oral delta9-tetrahydrocannabinol on specific airway conductance in asthmatic subjects. Tashkin DP, Shapiro BJ, Frank IM. 1974 Cannabis;Delta-9-THC;Cannabidiol Controlled study Smoked marijuana and oral THC caused significant bronchodilation of at least 2 hours duration.
Show Spasticity;Spinal cord injury;Pain The perceived effects of marijuana on spinal cord injured males. Dunn M, Davis R. 1974 Cannabis Survey Decrease in pain and spasticity.
Show Pain Marihuana and pain. Hill SY, Schwin R, Goodwin DW, Powell B. 1974 Cannabis Controlled study Cannabis increased pain sensitivity
Show Glaucoma Marihuana smoking and intraocular pressure. Hepler RS, Frank IR 1971 Cannabis Open study 9 of 11 had drop in intraocular pressure of 16-45%
Show Dependency/withdrawal Cannabis substitution. An adjunctive therapeutic tool in the treatment of alcoholism. Mikuriya TH 1970 Cannabis Uncontrolled case report Marijuana consumption may help to decrease alcolholic intake.

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